Paul Mohapel

Neuronal apoptosis after brief and prolonged seizures. (2002)

Bengzon, Johan, Mohapel, Paul, Ekdahl, Christine T, Lindvall, Olle

Evidence has accumulated that apoptotic cell death contributes to brain damage following experimental seizures. A substantial number of degenerating neurons within limbic regions display...

Electroconvulsive seizures increase hippocampal neurogenesis after chronic corticosterone treatment. (2002)

Hellsten, Johan, Wennström, Malin, Mohapel, Paul, Ekdahl, Christine T, Bengzon, Johan, Tingström, Anders

Major depression is often associated with elevated glucocorticoid levels. High levels of glucocorticoids reduce neurogenesis in the adult rat hippocampus. Electroconvulsive seizures (ECS) can enhance...

Caspase-mediated death of newly formed neurons in the adult rat dentate gyrus following status epilepticus. (2002)

Ekdahl, Christine T., Mohapel, Paul, Weber, Ekkehard, Bahr, Ben, Blomgren, Klas, Lindvall, Olle

A large proportion of cells that proliferate in the adult dentate gyrus under normal conditions or in response to brain insults exhibit only short-term survival. Here, we sought to determine which...

Development and persistence of kindling epilepsy are impaired in mice lacking glial cell line-derived neurotrophic factor family receptor α2

Nanobashvili, Avtandil, Airaksinen, Matti S., Kokaia, Merab, Rossi, Jari, Asztély, Fredrik, Olofsdotter, Klara, ...

Seizure activity regulates gene expression for glial cell line-derived neurotrophic factor (GDNF) and neurturin (NRTN), and their receptor components, the transmembrane c-Ret tyrosine kinase and the...

No evidence for new dopaminergic neurons in the adult mammalian substantia nigra

Frielingsdorf, Helena, Schwarz, Katherine, Brundin, Patrik, Mohapel, Paul

A recent report by Zhao et al. [Zhao, M., Momma, S., Delfani, K., Carlen, M., Cassidy, R. M., Johansson, C. B., Brismar, H., Shupliakov, O., Frisen, J. & Janson, A. M. (2003) Proc. Natl. Acad. Sci....

Development and persistence of kindling epilepsy are impaired in mice lacking glial cell line-derived neurotrophic factor family receptor α2

Nanobashvili, Avtandil, Airaksinen, Matti S., Kokaia, Merab, Rossi, Jari, Asztély, Fredrik, Olofsdotter, Klara, ...

Seizure activity regulates gene expression for glial cell line-derived neurotrophic factor (GDNF) and neurturin (NRTN), and their receptor components, the transmembrane c-Ret tyrosine kinase and the...

No evidence for new dopaminergic neurons in the adult mammalian substantia nigra

Frielingsdorf, Helena, Schwarz, Katherine, Brundin, Patrik, Mohapel, Paul

A recent report by Zhao et al. [Zhao, M., Momma, S., Delfani, K., Carlen, M., Cassidy, R. M., Johansson, C. B., Brismar, H., Shupliakov, O., Frisen, J. & Janson, A. M. (2003) Proc. Natl. Acad. Sci....