Paul E. G. Kristjansen

Improved Effect of an Antiangiogenic Tyrosine Kinase Inhibitor (SU5416) by Combinations with Fractionated Radiotherapy or Low Molecular Weight Heparin1

Lund, Eva L, Olsen, Minna W B, Lipson, Kenneth E, McMahon, Gerald, Howlett, Anthony R, Kristjansen, Paul E G

The effect of combining SU5416 with fractionated radiotherapy or with low molecular weight (LMW) heparin (dalteparin) was studied in U87 human glioblastoma xenografts in nude mice. SU5416 is...

Coregulation of Glucose Uptake and Vascular Endothelial Growth Factor (VEGF) in Two Small-Cell Lung Cancer (SCLC) Sublines In Vivo and In Vitro1

Pedersen, Minna W B, Holm, Søren, Lund, Eva L, Højgaard, Liselotte, Kristjansen, Paul E G

We examined the relationship between 18F- labeled 2-fluro-2-deoxy-d-glucose (FDG) uptake, and expression of glucose transporters (GLUTs) in two human small-cell lung cancer (SCLC) lines CPH 54A and...

Quantitative Estimates of Vascularity in Solid Tumors by Non-Invasive Near-Infrared Spectroscopy1

Kragh, Michael, Quistorff, Bjørn, Lund, Eva L, Kristjansen, Paul E G

We examined the relationship between non-invasive estimates of the tumor hemoglobin concentration by near-infrared spectroscopy (NIRS) and histological scores of tumor vascularity by Chalkley counts...

Acute Effects of Vascular Modifying Agents in Solid Tumors Assessed by Noninvasive Laser Doppler Flowmetry and Near Infrared Spectroscopy1

Kragh, Michael, Quistorff, Bjørn, Horsman, Michael R, Kristjansen, Paul E G

The potential of noninvasive laser Doppler flowmetry (LDF) and near infrared spectroscopy (NIRS) to detect acute effects of different vascular-modifying agents on perfusion and blood volume in tumors...

Angiopoietin-4 Inhibits Angiogenesis and Reduces Interstitial Fluid Pressure1

Olsen, Minna W B, Ley, Carsten D, Junker, Nanna, Hansen, Anker J, Lund, Eva L, Kristjansen, Paul E G

Angiopoietins (Ang) are involved in the remodeling, maturation, and stabilization of the vascular network. Ang-4 was discovered more recently; thus, its effect on angiogenesis and its interplay with...

Improved Effect of an Antiangiogenic Tyrosine Kinase Inhibitor (SU5416) by Combinations with Fractionated Radiotherapy or Low Molecular Weight Heparin1

Lund, Eva L, Olsen, Minna W B, Lipson, Kenneth E, McMahon, Gerald, Howlett, Anthony R, Kristjansen, Paul E G

The effect of combining SU5416 with fractionated radiotherapy or with low molecular weight (LMW) heparin (dalteparin) was studied in U87 human glioblastoma xenografts in nude mice. SU5416 is...

Coregulation of Glucose Uptake and Vascular Endothelial Growth Factor (VEGF) in Two Small-Cell Lung Cancer (SCLC) Sublines In Vivo and In Vitro1

Pedersen, Minna W B, Holm, Søren, Lund, Eva L, Højgaard, Liselotte, Kristjansen, Paul E G

We examined the relationship between 18F- labeled 2-fluro-2-deoxy-d-glucose (FDG) uptake, and expression of glucose transporters (GLUTs) in two human small-cell lung cancer (SCLC) lines CPH 54A and...

Quantitative Estimates of Vascularity in Solid Tumors by Non-Invasive Near-Infrared Spectroscopy1

Kragh, Michael, Quistorff, Bjørn, Lund, Eva L, Kristjansen, Paul E G

We examined the relationship between non-invasive estimates of the tumor hemoglobin concentration by near-infrared spectroscopy (NIRS) and histological scores of tumor vascularity by Chalkley counts...

Acute Effects of Vascular Modifying Agents in Solid Tumors Assessed by Noninvasive Laser Doppler Flowmetry and Near Infrared Spectroscopy1

Kragh, Michael, Quistorff, Bjørn, Horsman, Michael R, Kristjansen, Paul E G

The potential of noninvasive laser Doppler flowmetry (LDF) and near infrared spectroscopy (NIRS) to detect acute effects of different vascular-modifying agents on perfusion and blood volume in tumors...

Angiopoietin-4 Inhibits Angiogenesis and Reduces Interstitial Fluid Pressure1

Olsen, Minna W B, Ley, Carsten D, Junker, Nanna, Hansen, Anker J, Lund, Eva L, Kristjansen, Paul E G

Angiopoietins (Ang) are involved in the remodeling, maturation, and stabilization of the vascular network. Ang-4 was discovered more recently; thus, its effect on angiogenesis and its interplay with...

Early Effects of Combretastatin-A4 Disodium Phosphate on Tumor Perfusion and Interstitial Fluid Pressure12

Ley, Carsten D, Horsman, Michael R, Kristjansen, Paul E G

Combretastatin-A4 disodium phosphate (CA4DP) is a vascular-disruptive agent that causes an abrupt decrease in tumor blood flow. The direct actions of CA4DP include increases in vascular permeability...