Rines, Daniel R, Gomez-Ferreria, Maria, Zhou, Yingyao, DeJesus, Paul, Grob, Seanna, Batalov, Serge, ...
Abstract Background The mitotic spindle is a complex mechanical apparatus required for accurate segregation of sister chromosomes during mitosis. We designed a genetic screen using automated...
Genome-scale functional profiling of the mammalian AP-1 signaling pathway
Chanda, Sumit K., White, Suhaila, Orth, Anthony P., Reisdorph, Richard, Miraglia, Loren, Thomas, Russell S., ...
Large-scale functional genomics approaches are fundamental to the characterization of mammalian transcriptomes annotated by genome sequencing projects. Although current high-throughput strategies...
Identification of p53 regulators by genome-wide functional analysis
Huang, Qihong, Raya, Angel, DeJesus, Paul, Chao, Sheng-Hao, Quon, Kim C., Caldwell, Jeremy S., ...
The p53 tumor-suppressor protein is a critical mediator of cellular growth arrest and the induction of apoptosis. To identify proteins involved in the modulation of p53 transcriptional activity, a...
Genome-scale functional profiling of the mammalian AP-1 signaling pathway
Chanda, Sumit K., White, Suhaila, Orth, Anthony P., Reisdorph, Richard, Miraglia, Loren, Thomas, Russell S., ...
Large-scale functional genomics approaches are fundamental to the characterization of mammalian transcriptomes annotated by genome sequencing projects. Although current high-throughput strategies...
Identification of p53 regulators by genome-wide functional analysis
Huang, Qihong, Raya, Angel, DeJesus, Paul, Chao, Sheng-Hao, Quon, Kim C., Caldwell, Jeremy S., ...
The p53 tumor-suppressor protein is a critical mediator of cellular growth arrest and the induction of apoptosis. To identify proteins involved in the modulation of p53 transcriptional activity, a...
Rines, Daniel R, Gomez-Ferreria, Maria Ana, Zhou, Yingyao, DeJesus, Paul, Grob, Seanna, Batalov, Serge, ...
A loss-of-function screen for siRNAs that arrest human cells in metaphase reveals genes involved in mitotic spindle integrity.