Genome-wide association study identifies novel breast cancer susceptibility loci (2007)
Easton, Douglas F., Pooley, Karen A., Dunning, Alison M., Pharoah, Paul D.P., Thompson, Deborah, Ballinger, Dennis G., ...
Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility to the disease. Known susceptibility genes account for less than 25% of the familial risk of breast...
Genome-wide association study identifies novel breast cancer susceptibility loci (2007)
Easton, Douglas F., Pooley, Karen A., Dunning, Alison M., Pharoah, Paul D. P., Thompson, Deborah, Ballinger, Dennis G., ...
Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility to the disease. Known susceptibility genes account for less than 25% of the familial risk of breast...
Association between Common Variation in 120 Candidate Genes and Breast Cancer Risk
Pharoah, Paul D. P, Tyrer, Jonathan, Dunning, Alison M, Easton, Douglas F, Ponder, Bruce A. J
Association studies in candidate genes have been widely used to search for common low penetrance susceptibility alleles, but few definite associations have been established. We have conducted...
Daigo, Yataro, Chin, Suet-Feung, Gorringe, Kylie L., Bobrow, Lynda G., Ponder, Bruce A. J., Pharoah, Paul D. P., ...
We have developed a protocol for degenerate oligonucleotide-primed-polymerase chain reaction-based array comparative genomic hybridization (array CGH) that, when combined with a laser microdissection...
Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer
Ito, Yoko, Koessler, Thibaud, Ibrahim, Ashraf E.K., Rai, Sushma, Vowler, Sarah L., Abu-Amero, Sayeda, ...
The imprinted insulin-like growth factor 2 (IGF2) gene is expressed predominantly from the paternal allele. Loss of imprinting (LOI) associated with hypomethylation at the promoter proximal sequence...