Patricia P. Smith

Human Cytomegalovirus Infection of Caco-2 Cells Occurs at the Basolateral Membrane and Is Differentiation State Dependent

Jarvis, Michael A., Wang, C. Edward, Meyers, Heather L., Smith, Patricia P., Corless, Christopher L., Henderson, Gavin J., ...

Epithelial cells are known to be a major target for human cytomegalovirus (HCMV) infection; however, the analysis of virus-cell interactions has been difficult to approach due to the lack of in vitro...

Long-Term Infection and Transformation of Dermal Microvascular Endothelial Cells by Human Herpesvirus 8

Moses, Ashlee V., Fish, Kenneth N., Ruhl, Rebecca, Smith, Patricia P., Strussenberg, Joanne G., Zhu, Liangjin, ...

Human herpesvirus 8 (HHV8) infects Kaposi’s sarcoma (KS) spindle cells in situ, as well as the lesional endothelial cells considered to be spindle cell precursors. The HHV8 genome contains several...

Reactivation of Latent Human Cytomegalovirus in CD14+ Monocytes Is Differentiation Dependent

Söderberg-Nauclér, Cecilia, Streblow, Daniel N., Fish, Kenneth N., Allan-Yorke, Justine, Smith, Patricia P., Nelson, Jay A.

We have previously demonstrated reactivation of latent human cytomegalovirus (HCMV) in myeloid lineage cells obtained from healthy donors. Virus was obtained from allogenically stimulated...

Human Cytomegalovirus-Encoded G Protein-Coupled Receptor US28 Mediates Smooth Muscle Cell Migration through Gα12

Melnychuk, Ryan M., Streblow, Daniel N., Smith, Patricia P., Hirsch, Alec J., Pancheva, Dora, Nelson, Jay A.

Coupling of G proteins to ligand-engaged chemokine receptors is the paramount event in G-protein-coupled receptor signal transduction. Previously, we have demonstrated that the human...

Human Cytomegalovirus Infection of Caco-2 Cells Occurs at the Basolateral Membrane and Is Differentiation State Dependent

Jarvis, Michael A., Wang, C. Edward, Meyers, Heather L., Smith, Patricia P., Corless, Christopher L., Henderson, Gavin J., ...

Epithelial cells are known to be a major target for human cytomegalovirus (HCMV) infection; however, the analysis of virus-cell interactions has been difficult to approach due to the lack of in vitro...

Long-Term Infection and Transformation of Dermal Microvascular Endothelial Cells by Human Herpesvirus 8

Moses, Ashlee V., Fish, Kenneth N., Ruhl, Rebecca, Smith, Patricia P., Strussenberg, Joanne G., Zhu, Liangjin, ...

Human herpesvirus 8 (HHV8) infects Kaposi’s sarcoma (KS) spindle cells in situ, as well as the lesional endothelial cells considered to be spindle cell precursors. The HHV8 genome contains several...

Reactivation of Latent Human Cytomegalovirus in CD14+ Monocytes Is Differentiation Dependent

Söderberg-Nauclér, Cecilia, Streblow, Daniel N., Fish, Kenneth N., Allan-Yorke, Justine, Smith, Patricia P., Nelson, Jay A.

We have previously demonstrated reactivation of latent human cytomegalovirus (HCMV) in myeloid lineage cells obtained from healthy donors. Virus was obtained from allogenically stimulated...

Human Cytomegalovirus-Encoded G Protein-Coupled Receptor US28 Mediates Smooth Muscle Cell Migration through Gα12

Melnychuk, Ryan M., Streblow, Daniel N., Smith, Patricia P., Hirsch, Alec J., Pancheva, Dora, Nelson, Jay A.

Coupling of G proteins to ligand-engaged chemokine receptors is the paramount event in G-protein-coupled receptor signal transduction. Previously, we have demonstrated that the human...