Nicolas Bischler

Localization of the yeast RNA polymerase I-specific subunits

Bischler, Nicolas, Brino, Laurent, Carles, Christophe, Riva, Michel, Tschochner, Herbert, Mallouh, Véronique, ...

The spatial distribution of four subunits specifically associated to the yeast DNA-dependent RNA polymerase I (RNA pol I) was studied by electron microscopy. A structural model of the native enzyme...

The recruitment of RNA polymerase I on rDNA is mediated by the interaction of the A43 subunit with Rrn3

Peyroche, Gérald, Milkereit, Philipp, Bischler, Nicolas, Tschochner, Herbert, Schultz, Patrick, Sentenac, André, ...

RNA polymerase I (Pol I) is dedicated to transcription of the large ribosomal DNA (rDNA). The mechanism of Pol I recruitment onto rDNA promoters is poorly understood. Here we present evidence that...

Localization of the yeast RNA polymerase I-specific subunits

Bischler, Nicolas, Brino, Laurent, Carles, Christophe, Riva, Michel, Tschochner, Herbert, Mallouh, Véronique, ...

The spatial distribution of four subunits specifically associated to the yeast DNA-dependent RNA polymerase I (RNA pol I) was studied by electron microscopy. A structural model of the native enzyme...

The recruitment of RNA polymerase I on rDNA is mediated by the interaction of the A43 subunit with Rrn3

Peyroche, Gérald, Milkereit, Philipp, Bischler, Nicolas, Tschochner, Herbert, Schultz, Patrick, Sentenac, André, ...

RNA polymerase I (Pol I) is dedicated to transcription of the large ribosomal DNA (rDNA). The mechanism of Pol I recruitment onto rDNA promoters is poorly understood. Here we present evidence that...

Kinetic and crystallographic studies on 2-(β-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site

Chrysina, Evangelia D., Kosmopoulou, Magda N., Tiraidis, Constantinos, Kardakaris, Rozina, Bischler, Nicolas, Leonidas, Demetres D., ...

In an attempt to identify leads that would enable the design of inhibitors with enhanced affinity for glycogen phosphorylase (GP), that might control hyperglycaemia in type 2 diabetes, three new...

Association of Yeast RNA Polymerase I with a Nucleolar Substructure Active in Rrna Synthesis and Processing

Fath, Stephan, Milkereit, Philipp, Podtelejnikov, Alexandre V., Bischler, Nicolas, Schultz, Patrick, Bier, Mirko, ...

A novel ribonucleoprotein complex enriched in nucleolar proteins was purified from yeast extracts and constituents were identified by mass spectrometry. When isolated from rapidly growing cells, the...