Nektarios Tavernarakis

Nemo: a computational tool for analyzing nematode locomotion (2008)

Tsibidis, George D., Tavernarakis, Nektarios

The nematode Caenorhabditis elegans responds to an impressive range of chemical, mechanical and thermal stimuli and is extensively used to investigate the molecular mechanisms that mediate...

Nemo: a computational tool for analyzing nematode locomotion (2007)

Tsibidis, George D, Tavernarakis, Nektarios

Abstract Background The nematode Caenorhabditis elegans responds to an impressive range of chemical, mechanical and thermal stimuli and is extensively used to investigate the molecular mechanisms...

Genome-wide investigation reveals pathogen-specific and shared signatures in the response of C. elegans to infection. (2007)

Wong, Daniel, Bazopoulou, Daphne, Pujol, Nathalie, Tavernarakis, Nektarios, Ewbank, Jonathan

ABSTRACT: BACKGROUND: There are striking similarities between the innate immune systems of invertebrates and vertebrates. Caenorhabditis elegans is increasingly used as a model for the study of...

Genome-wide investigation reveals pathogen-specific and shared signatures in the response of C. elegans to infection. (2007)

Wong, Daniel, Bazopoulou, Daphne, Pujol, Nathalie, Tavernarakis, Nektarios, Ewbank, Jonathan

ABSTRACT: BACKGROUND: There are striking similarities between the innate immune systems of invertebrates and vertebrates. Caenorhabditis elegans is increasingly used as a model for the study of...

Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegansto infection (2007)

Wong, Daniel, Bazopoulou, Daphne, Pujol, Nathalie, Tavernarakis, Nektarios, Ewbank, Jonathan J

Abstract Background There are striking similarities between the innate immune systems of invertebrates and vertebrates. Caenorhabditis elegans is increasingly used as a model for the study of innate...

Eating less to live longer (2002)

Tavernarakis, Nektarios

Abstract Restricting their intake of calories can further extend the lifespan of long-lived Ames dwarf mice

Interfering with RNA interference (2002)

Tavernarakis, Nektarios

Abstract Adenine deamination in double-stranded RNA by specific adenine deaminases efficiently blocks RNA interference in vitro

More neuropeptides in C. elegans (2002)

Tavernarakis, Nektarios

Abstract A genome-wide scan has revealed multiple conserved groups of neuropeptide genes in the nematode Caenorhabditis elegans

Genetically targeted cell disruption in Caenorhabditis elegans

Harbinder, S., Tavernarakis, Nektarios, Herndon, Laura A., Kinnell, Maud, Xu, Si Qun, Fire, Andrew, ...

The elimination of identified cells is a powerful tool for investigating development and system function. Here we report on genetically mediated cell disruption effected by the toxic Caenorhabditis...

Induction of RNA interference in Caenorhabditis elegans by RNAs derived from plants exhibiting post-transcriptional gene silencing

Boutla, Alexandra, Kalantidis, Kriton, Tavernarakis, Nektarios, Tsagris, Mina, Tabler, Martin

The term ‘gene silencing’ refers to transcriptional and post-transcriptional control of gene expression. Related processes are found across kingdoms in plants and animals. We intended to test...

UNC-4/UNC-37-dependent repression of motor neuron-specific genes controls synaptic choice in Caenorhabditis elegans

Winnier, Angela R., Meir, James Y.-J., Ross, Jennifer M., Tavernarakis, Nektarios, Driscoll, Monica, Ishihara, Takeshi, ...

The UNC-4 homeoprotein and the Groucho-like corepressor UNC-37 specify synaptic choice in the Caenorhabditis elegans motor neuron circuit. In unc-4 mutants, VA motor neurons are miswired with inputs...

Death by necrosis: Uncontrollable catastrophe, or is there order behind the chaos?

Syntichaki, Popi, Tavernarakis, Nektarios

Cells suffer necrotic death when exposed to extreme environmental conditions, adverse and excessive stimuli, or when deleterious mutations are encoded in their genetic material. Unlike apoptosis,...

The Genomes On Line Database (GOLD) v.2: a monitor of genome projects worldwide

Liolios, Konstantinos, Tavernarakis, Nektarios, Hugenholtz, Philip, Kyrpides, Nikos C.

The Genomes On Line Database (GOLD) is a web resource for comprehensive access to information regarding complete and ongoing genome sequencing projects worldwide. The database currently incorporates...

Genetically targeted cell disruption in Caenorhabditis elegans

Harbinder, S., Tavernarakis, Nektarios, Herndon, Laura A., Kinnell, Maud, Xu, Si Qun, Fire, Andrew, ...

The elimination of identified cells is a powerful tool for investigating development and system function. Here we report on genetically mediated cell disruption effected by the toxic Caenorhabditis...

Induction of RNA interference in Caenorhabditis elegans by RNAs derived from plants exhibiting post-transcriptional gene silencing

Boutla, Alexandra, Kalantidis, Kriton, Tavernarakis, Nektarios, Tsagris, Mina, Tabler, Martin

The term ‘gene silencing’ refers to transcriptional and post-transcriptional control of gene expression. Related processes are found across kingdoms in plants and animals. We intended to test...

UNC-4/UNC-37-dependent repression of motor neuron-specific genes controls synaptic choice in Caenorhabditis elegans

Winnier, Angela R., Meir, James Y.-J., Ross, Jennifer M., Tavernarakis, Nektarios, Driscoll, Monica, Ishihara, Takeshi, ...

The UNC-4 homeoprotein and the Groucho-like corepressor UNC-37 specify synaptic choice in the Caenorhabditis elegans motor neuron circuit. In unc-4 mutants, VA motor neurons are miswired with inputs...

Death by necrosis: Uncontrollable catastrophe, or is there order behind the chaos?

Syntichaki, Popi, Tavernarakis, Nektarios

Cells suffer necrotic death when exposed to extreme environmental conditions, adverse and excessive stimuli, or when deleterious mutations are encoded in their genetic material. Unlike apoptosis,...

The Genomes On Line Database (GOLD) v.2: a monitor of genome projects worldwide

Liolios, Konstantinos, Tavernarakis, Nektarios, Hugenholtz, Philip, Kyrpides, Nikos C.

The Genomes On Line Database (GOLD) is a web resource for comprehensive access to information regarding complete and ongoing genome sequencing projects worldwide. The database currently incorporates...

The role of synaptic ion channels in synaptic plasticity

Voglis, Giannis, Tavernarakis, Nektarios

The nervous system receives a large amount of information about the environment through elaborate sensory routes. Processing and integration of these wide-ranging inputs often results in long-term...

Lysosomal biogenesis and function is critical for necrotic cell death in Caenorhabditis elegans

Artal-Sanz, Marta, Samara, Chrysanthi, Syntichaki, Popi, Tavernarakis, Nektarios

Necrotic cell death is defined by distinctive morphological characteristics that are displayed by dying cells (Walker, N.I., B.V. Harmon, G.C. Gobe, and J.F. Kerr. 1988. Methods Achiev. Exp. Pathol....

The Genomes On Line Database (GOLD) in 2007: status of genomic and metagenomic projects and their associated metadata

Liolios, Konstantinos, Mavromatis, Konstantinos, Tavernarakis, Nektarios, Kyrpides, Nikos C.

The Genomes On Line Database (GOLD) is a comprehensive resource that provides information on genome and metagenome projects worldwide. Complete and ongoing projects and their associated metadata can...

Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection

Wong, Daniel, Bazopoulou, Daphne, Pujol, Nathalie, Tavernarakis, Nektarios, Ewbank, Jonathan J

Microarray analysis of the transcriptional response of C. elegans to four bacterial pathogens revealed that different infections trigger responses, some of which are common to all four pathogens,...

Functional and physical interaction between Bcl-XL and a BH3-like domain in Beclin-1

Maiuri, M Chiara, Le Toumelin, Gaëtane, Criollo, Alfredo, Rain, Jean-Christophe, Gautier, Fabien, Juin, Philippe, ...

The anti-apoptotic proteins Bcl-2 and Bcl-XL bind and inhibit Beclin-1, an essential mediator of autophagy. Here, we demonstrate that this interaction involves a BH3 domain within Beclin-1 (residues...