Requirements for FGF3 and FGF10 during inner ear formation (2003)
Alvarez, Yolanda, Alonso, Maria Teresa, Vendrell, Victor, Zelarayan, Laura Cecilia, Chamero, Pablo, Theil, Thomas, ...
Members of the fibroblast growth factor (FGF) gene family control formation of the body plan and organogenesis in vertebrates. FGF3 is expressed in the developing hindbrain and has been shown to be...
Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp)
Bösl, Michael R., Takaku, Kazuaki, Oshima, Masanobu, Nishimura, Susumu, Taketo, Makoto M.
Selenoprotein biosynthesis is mediated by tRNASec, which inserts selenocysteine at UGA codons in a complex, context-specific manner. This opal suppressor serves in the conversion of serine to...
Placental Failure in Mice Lacking the Mammalian Homolog of Glial Cells Missing, GCMa
Schreiber, Jörg, Riethmacher-Sonnenberg, Eva, Riethmacher, Dieter, Tuerk, Elisabeth E., Enderich, Janna, Bösl, Michael R., ...
The GCM family of transcription factors consists of Drosophila melanogaster GCM, an important regulator of gliogenesis in the fly, and its two mammalian homologs, GCMa and GCMb. To clarify the...
Idiopathic Weight Reduction in Mice Deficient in the High-Mobility-Group Transcription Factor Sox8
Sock, Elisabeth, Schmidt, Katy, Hermanns-Borgmeyer, Irm, Bösl, Michael R., Wegner, Michael
Sox8, Sox9, and Sox10 constitute subgroup E within the Sox family of transcription factors. Many Sox proteins are essential regulators of development. Sox9, for instance, is required for...
Bösl, Michael R., Stein, Valentin, Hübner, Christian, Zdebik, Anselm A., Jordt, Sven-Eric, Mukhopadhyay, Amal K., ...
The functions of some CLC Cl– channels are evident from human diseases that result from their mutations, but the role of the broadly expressed ClC-2 Cl– channel is less clear. Several important...
Impaired renal Na+ retention in the sgk1-knockout mouse
Wulff, Peer, Vallon, Volker, Huang, Dan Yang, Völkl, Harald, Yu, Fang, Richter, Kerstin, ...
The serum- and glucocorticoid-regulated kinase (sgk1) is induced by mineralocorticoids and, in turn, upregulates heterologously expressed renal epithelial Na+ channel (ENaC) activity in Xenopus...
Sock, Elisabeth, Rettig, Stefanie D., Enderich, Janna, Bösl, Michael R., Tamm, Ernst R., Wegner, Michael
The high-mobility-group domain-containing transcription factor Sox11 is expressed transiently during embryonic development in many tissues that undergo inductive remodeling. Here we have analyzed the...
Friedrich, Ralf P., Schlierf, Beate, Tamm, Ernst R., Bösl, Michael R., Wegner, Michael
For differentiation, Schwann cells rely on the class III POU domain transcription factor Oct-6, which is expressed transiently when Schwann cells have established a one-to-one relation with axons but...
Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp)
Bösl, Michael R., Takaku, Kazuaki, Oshima, Masanobu, Nishimura, Susumu, Taketo, Makoto M.
Selenoprotein biosynthesis is mediated by tRNASec, which inserts selenocysteine at UGA codons in a complex, context-specific manner. This opal suppressor serves in the conversion of serine to...
Placental Failure in Mice Lacking the Mammalian Homolog of Glial Cells Missing, GCMa
Schreiber, Jörg, Riethmacher-Sonnenberg, Eva, Riethmacher, Dieter, Tuerk, Elisabeth E., Enderich, Janna, Bösl, Michael R., ...
The GCM family of transcription factors consists of Drosophila melanogaster GCM, an important regulator of gliogenesis in the fly, and its two mammalian homologs, GCMa and GCMb. To clarify the...
Idiopathic Weight Reduction in Mice Deficient in the High-Mobility-Group Transcription Factor Sox8
Sock, Elisabeth, Schmidt, Katy, Hermanns-Borgmeyer, Irm, Bösl, Michael R., Wegner, Michael
Sox8, Sox9, and Sox10 constitute subgroup E within the Sox family of transcription factors. Many Sox proteins are essential regulators of development. Sox9, for instance, is required for...
Bösl, Michael R., Stein, Valentin, Hübner, Christian, Zdebik, Anselm A., Jordt, Sven-Eric, Mukhopadhyay, Amal K., ...
The functions of some CLC Cl– channels are evident from human diseases that result from their mutations, but the role of the broadly expressed ClC-2 Cl– channel is less clear. Several important...
Impaired renal Na+ retention in the sgk1-knockout mouse
Wulff, Peer, Vallon, Volker, Huang, Dan Yang, Völkl, Harald, Yu, Fang, Richter, Kerstin, ...
The serum- and glucocorticoid-regulated kinase (sgk1) is induced by mineralocorticoids and, in turn, upregulates heterologously expressed renal epithelial Na+ channel (ENaC) activity in Xenopus...
Sock, Elisabeth, Rettig, Stefanie D., Enderich, Janna, Bösl, Michael R., Tamm, Ernst R., Wegner, Michael
The high-mobility-group domain-containing transcription factor Sox11 is expressed transiently during embryonic development in many tissues that undergo inductive remodeling. Here we have analyzed the...
Friedrich, Ralf P., Schlierf, Beate, Tamm, Ernst R., Bösl, Michael R., Wegner, Michael
For differentiation, Schwann cells rely on the class III POU domain transcription factor Oct-6, which is expressed transiently when Schwann cells have established a one-to-one relation with axons but...
Gebhard, Sonja, Hattori, Takako, Bauer, Eva, Bösl, Michael R., Schlund, Britta, Pöschl, Ernst, ...
During endochondral ossification hypertrophic chondrocytes in the growth plate of fetal long bones, ribs and vertebrae play a key role in preparing growth plate cartilage for replacement by bone. In...
Murine CXCL14 Is Dispensable for Dendritic Cell Function and Localization within Peripheral Tissues▿
Meuter, Simone, Schaerli, Patrick, Roos, Regula Stuber, Brandau, Oliver, Bösl, Michael R., Von Andrian, Ulrich H., ...
Dendritic cells (DCs) have long been recognized as key regulators of immune responses. However, the process of their recruitment to peripheral tissues and turnover during homeostasis remains largely...
Potzner, Michaela R., Griffel, Carola, Lütjen-Drecoll, Elke, Bösl, Michael R., Wegner, Michael, Sock, Elisabeth
The highly related transcription factors Sox4 and Sox11 are both expressed in oligodendrocyte precursors. Yet whether they have a function in oligodendrocyte development is unknown. By overexpressing...
Werner, Torsten, Hammer, Alexander, Wahlbuhl, Mandy, Bösl, Michael R., Wegner, Michael
Expression and function of the transcription factor Sox10 is predominant in neural crest cells, its derivatives and in oligodendrocytes. To understand how Sox10 expression is regulated during...
Cytokeratins 8 and 19 in the Mouse Placental Development
Tamai, Yoshitaka, Ishikawa, Tomo-o, Bösl, Michael R., Mori, Masahiko, Nozaki, Masami, Baribault, Heléne, ...
To investigate the expression and biological roles of cytokeratin 19 (K19) in development and in adult tissues, we inactivated the mouse K19 gene (Krt1-19) by inserting a bacterial β-galactosidase...
Fritsch, Anja, Loeckermann, Stefan, Kern, Johannes S., Braun, Attila, Bösl, Michael R., Bley, Thorsten A., ...
Dystrophic epidermolysis bullosa (DEB) is a severe skin fragility disorder associated with trauma-induced blistering, progressive soft tissue scarring, and increased risk of skin cancer. DEB is...