Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk (2001)
Chamorro, Mario, Czar, Michael J, Debnath, Jayanta, Cheng, Genhong, Lenardo, Michael J, Varmus, Harold E, ...
Abstract Background The Tec family kinases are implicated in signaling from lymphocyte antigen receptors and are activated following phosphorylation by Src kinases. For most Tec kinases, this...
Pratt, William B., Czar, Michael J., Stancato, Louis F., Owens, Janet K.
In many cells, the glucocorticoid receptor undergoes rapid steroid-mediated translocation from the cytoplasm to the nucleus, and this receptor is an excellent model for studying the mechanism of...
DNA-binding and non-DNA-binding forms of the transformed glucocorticoid receptor (1992)
Hutchinson, Kevin A., Matic, Gordana, Czar, Michael J., Pratt, William B.
In this work we have probed the mechanism responsible for two non-DNA-binding states of the mouse glucocorticoid receptor. In the first case, transformed receptors were treated with hydrogen...
An alternate passing paint pattern / (1975)
Czar, Michael J., Jacobs, Donald J.
Essay (M.Eng.)--Pennsylvania State University, 1975.
Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk
Chamorro, Mario, Czar, Michael J, Debnath, Jayanta, Cheng, Genhong, Lenardo, Michael J, Varmus, Harold E, ...
Czar, Michael J., Kersh, Ellen N., Mijares, Lilia A., Lanier, Gibson, Lewis, Jennifer, Yap, George, ...
We have introduced a targeted mutation in SH2D1A/DSHP/SAP, the gene responsible for the human genetic disorder X-linked lymphoproliferative disease (XLP). SLAM-associated protein (SAP)-deficient mice...
Shan, Xiaochuan, Czar, Michael J., Bunnell, Stephen C., Liu, Pinghu, Liu, Yusen, Schwartzberg, Pamela L., ...
Pleckstrin homology (PH) domain binding to D3-phosphorylated phosphatidylinositides (PI) provides a reversible means of recruiting proteins to the plasma membrane, with the resultant change in...
rlk/TXK Encodes Two Forms of a Novel Cysteine String Tyrosine Kinase Activated by Src Family Kinases
Debnath, Jayantha, Chamorro, Mario, Czar, Michael J., Schaeffer, Edward M., Lenardo, Michael J., Varmus, Harold E., ...
Rlk/Txk is a member of the BTK/Tec family of tyrosine kinases and is primarily expressed in T lymphocytes. Unlike other members of this kinase family, Rlk lacks a pleckstrin homology (PH) domain near...
Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk
Chamorro, Mario, Czar, Michael J, Debnath, Jayanta, Cheng, Genhong, Lenardo, Michael J, Varmus, Harold E, ...
Czar, Michael J., Kersh, Ellen N., Mijares, Lilia A., Lanier, Gibson, Lewis, Jennifer, Yap, George, ...
We have introduced a targeted mutation in SH2D1A/DSHP/SAP, the gene responsible for the human genetic disorder X-linked lymphoproliferative disease (XLP). SLAM-associated protein (SAP)-deficient mice...
Shan, Xiaochuan, Czar, Michael J., Bunnell, Stephen C., Liu, Pinghu, Liu, Yusen, Schwartzberg, Pamela L., ...
Pleckstrin homology (PH) domain binding to D3-phosphorylated phosphatidylinositides (PI) provides a reversible means of recruiting proteins to the plasma membrane, with the resultant change in...
rlk/TXK Encodes Two Forms of a Novel Cysteine String Tyrosine Kinase Activated by Src Family Kinases
Debnath, Jayantha, Chamorro, Mario, Czar, Michael J., Schaeffer, Edward M., Lenardo, Michael J., Varmus, Harold E., ...
Rlk/Txk is a member of the BTK/Tec family of tyrosine kinases and is primarily expressed in T lymphocytes. Unlike other members of this kinase family, Rlk lacks a pleckstrin homology (PH) domain near...