Michael F. Dunn

βQ114M and βT110V Mutations Reveal a Critically Important Role of the Substrate Α−Carboxylate Site in the Reaction Specificity of Tryptophan Synthase (2007)

Blumenstein, Lars, Domratcheva, Tatiana, Niks, Dimitri, Ngo, Huu, Seidel, Ralf, Dunn, Michael F., ...

In the PLP−requiring α2α2 tryptophan synthase complex, recognition of the substrate L−Ser at the β−site includes a loop structure (residues β110−115) extensively H−bonded to the...

Synthesis and Characterization of Allosteric Probes of Substrate Channeling in the Tryptophan Synthase Bienzyme Complex (2007)

Ngo, Huu, Harris, Rodney, Kimmich, Novelle, Casino, Patricia, Niks, Dimitri, Blumenstein, Lars, ...

Allosteric interactions regulate substrate channeling in Salmonella typhimurium tryptophan synthase. The channeling of indole between the Alpha− and ß−sites via the interconnecting 25 Å...

On the Structural Basis of the Catalytic Mechanism and the Regulation of the Alpha Subunit of Tryptophan Synthase from Salmonella typhimurium and BX1 from Maize, Two Evolutionarily Related Enzymes (2005)

Kulik, Victor, Hartmann, Elisabeth, Weyand, Michael, Frey, Marco, Gierl, Alfons, ...

Indole is a reaction intermediate in at least two biosynthetic pathways in maize seedlings. In the primary metabolism, the α−subunit (TSA) of the bifunctional tryptophan synthase (TRPS) catalyzes...

On the Structural Basis of the Catalytic Mechanism and the Regulation of the Alpha Subunit of Tryptophan Synthase from Salmonella typhimurium and BX1 from Maize, Two Evolutionarily Related Enzymes (2005)

Kulik, Victor, Hartmann, Elisabeth, Weyand, Michael, Frey, Marco, Gierl, Alfons, ...

Indole is a reaction intermediate in at least two biosynthetic pathways in maize seedlings. In the primary metabolism, the α−subunit (TSA) of the bifunctional tryptophan synthase (TRPS) catalyzes...

On the Role of αThr183 in the Allosteric Regulation and Catalytic Mechanism of Tryptophan Synthase (2002)

Kulik,Victor, Weyand,Michael, Seidel,Ralf, Niks,Dimitri, Arac,Demet, Dunn,Michael F., ...

The catalytic activity and substrate channeling of the pyridoxal 5-phosphate-dependent tryptophan synthase α 2β 2 complex is regulated by allosteric interactions that modulate the switching of the...

On the role of αThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase (2002)

Kulik,Victor, Weyand,Michael, Seidel,Ralf, Niks,Dimitri, Arac,Demet, Dunn,Michael F., ...

The catalytic activity and substrate channeling of the pyridoxal 5'-phosphate-dependent tryptophan synthase alpha(2)beta(2) complex is regulated by allosteric interactions that modulate the switching...

On the role of αThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase (2002)

Kulik, Victor, Weyand, Michael, Seidel, Ralf, Niks, Dimitri, Arac, Demet, Dunn, Michael F., ...

The catalytic activity and substrate channeling of the pyridoxal 5'-phosphate-dependent tryptophan synthase alpha(2)beta(2) complex is regulated by allosteric interactions that modulate the switching...

On the Role of αThr183 in the Allosteric Regulation and Catalytic Mechanism of Tryptophan Synthase (2002)

Kulik, Victor, Weyand, Michael, Seidel, Ralf, Niks, Dimitri, Arac, Demet, Dunn, Michael F., ...

The catalytic activity and substrate channeling of the pyridoxal 5-phosphate-dependent tryptophan synthase α 2β 2 complex is regulated by allosteric interactions that modulate the switching of the...

Certification Of Reusable Software Parts (1994)

Michael F. Dunn, John C. Knight

ion and encapsulation mechanisms. . Recursion semantics. . Efficiency, for example, of numeric and string processing functions. . Strength of type mechanism. . Approach to evaluation, lazy or eager....

AniA Regulates Reserve Polymer Accumulation and Global Protein Expression in Rhizobium etli

Encarnación, Sergio, Vargas, María Del Carmen, Dunn, Michael F., Dávalos, Araceli, Mendoza, Guillermo, Mora, Yolanda, ...

Previously, it was reported that the oxidative capacity and ability to grow on carbon sources such as pyruvate and glucose were severely diminished in the Rhizobium etli phaC::ΩSmr/Spr mutant CAR1,...

Effect of aniA (Carbon Flux Regulator) and phaC (Poly-β-Hydroxybutyrate Synthase) Mutations on Pyruvate Metabolism in Rhizobium etli

Dunn, Michael F., Araíza, Gisela, Encarnación, Sergio, Vargas, María Del Carmen, Mora, Jaime

The Rhizobium etli poly-β-hydroxybutyrate synthase (PhaC) mutant SAM100 grows poorly with pyruvate as the carbon source. The inactivation of aniA, encoding a global carbon flux regulator, in SAM100...

Characterization of Exopolysaccharides Produced by Plant-Associated Fluorescent Pseudomonads

Fett, William F., Osman, Stanley F., Dunn, Michael F.

A total of 214 strains of plant-associated fluorescent pseudomonads were screened for the ability to produce the acidic exopolysaccharide (EPS) alginate on various solid media. The fluorescent...

Auxin Production by Plant-Pathogenic Pseudomonads and Xanthomonads

Fett, William F., Osman, Stanley F., Dunn, Michael F.

Pathogenic strains of Xanthomonas campestris pv. glycines which cause hypertrophy of leaf cells of susceptible soybean cultivars and nonpathogenic strains which do not cause hypertrophy were compared...

Exopolysaccharides Produced by Phytopathogenic Pseudomonas syringae Pathovars in Infected Leaves of Susceptible Hosts

Fett, William F., Dunn, Michael F.

Bacterial exopolysaccharide (EPS) was extracted from infected leaves of several host plants inoculated with phytopathogenic strains of Pseudomonas syringae pathovars. Extraction was by a facilitated...

AniA Regulates Reserve Polymer Accumulation and Global Protein Expression in Rhizobium etli

Encarnación, Sergio, Vargas, María Del Carmen, Dunn, Michael F., Dávalos, Araceli, Mendoza, Guillermo, Mora, Yolanda, ...

Previously, it was reported that the oxidative capacity and ability to grow on carbon sources such as pyruvate and glucose were severely diminished in the Rhizobium etli phaC::ΩSmr/Spr mutant CAR1,...

Effect of aniA (Carbon Flux Regulator) and phaC (Poly-β-Hydroxybutyrate Synthase) Mutations on Pyruvate Metabolism in Rhizobium etli

Dunn, Michael F., Araíza, Gisela, Encarnación, Sergio, Vargas, María Del Carmen, Mora, Jaime

The Rhizobium etli poly-β-hydroxybutyrate synthase (PhaC) mutant SAM100 grows poorly with pyruvate as the carbon source. The inactivation of aniA, encoding a global carbon flux regulator, in SAM100...

Characterization of Exopolysaccharides Produced by Plant-Associated Fluorescent Pseudomonads

Fett, William F., Osman, Stanley F., Dunn, Michael F.

A total of 214 strains of plant-associated fluorescent pseudomonads were screened for the ability to produce the acidic exopolysaccharide (EPS) alginate on various solid media. The fluorescent...

Auxin Production by Plant-Pathogenic Pseudomonads and Xanthomonads

Fett, William F., Osman, Stanley F., Dunn, Michael F.

Pathogenic strains of Xanthomonas campestris pv. glycines which cause hypertrophy of leaf cells of susceptible soybean cultivars and nonpathogenic strains which do not cause hypertrophy were compared...

Exopolysaccharides Produced by Phytopathogenic Pseudomonas syringae Pathovars in Infected Leaves of Susceptible Hosts

Fett, William F., Dunn, Michael F.

Bacterial exopolysaccharide (EPS) was extracted from infected leaves of several host plants inoculated with phytopathogenic strains of Pseudomonas syringae pathovars. Extraction was by a facilitated...

Structural signatures of the complex formed between 3-nitro-4-hydroxybenzoate and the Zn(II)-substituted R6 insulin hexamer

Olsen, Helle Birk, Leuenberger-Fisher, Melissa R., Kadima, Webe, Borchardt, Dan, Kaarsholm, Niels C., Dunn, Michael F.

3-Nitro-4-hydroxybenzoate (3N4H) is a probe of the structure and dynamics of the metal-centered His B10 assembly sites of the insulin hexamer. Each His B10 site consists of a ∼12 Å-long cavity...

Multichromosomal Genome Structure and Confirmation of Diazotrophy in Novel Plant-Associated Burkholderia Species▿

Martínez-Aguilar, Lourdes, Díaz, Rafael, Peña-Cabriales, Juan José, Dunn, Michael F., Caballero-Mellado, Jesús

Pulsed-field gel electrophoresis and 16S rRNA hybridization experiments showed that multichromosome genome structures and very large genome sizes (6.46 to 8.73 Mb) are prevalent in novel...