Michael D. Parker

Genetically Engineered, Live Attenuated Vaccines Protect Nonhuman Primates Against Aerosol Challenge with a Virulent IE Strain of Venezuelan Equine Encephalitis Virus (1998)

Reed, Douglas S., Lind, Cathleen M., Lackemeyer, Matthew G., Sullivan, Lawrence J., Pratt, William D., Parker, Michael D.

Two live, attenuated strains of Venezuelan equine encephalitis virus (VEE), IE1150K and V3526, were administered to macaques to determine if they could elicit protection against an aerosol challenge...

Viral Vectors for Use in the Development of Biodefense Vaccines (1998)

Lee, John S., Hadjipanayis, Angela G., Parker, Michael D.

The heightened concerns about bioterrorism and the use of biowarfare agents have prompted substantial increased efforts towards the development of vaccines against a wide range of organisms, toxins,...

Aerosol Exposure to Western Equine Encephalitis Virus Causes Fever and Encephalitis in Cynomolgus Macaques (1998)

Reed, Douglas S., Larsen, Tom, Sullivan, Lawrence J., Lind, Cathleen M., Lackemeyer, Matthew G., Pratt, William D., ...

Cynomolgus macaques were exposed by aerosol to a virulent strain of western equine encephalitis virus (WEEV). Between 4 and 6 days after exposure, macaques had a significantly elevated temperature...

Candidate Vaccine against Botulinum Neurotoxin Serotype A Derived from a Venezuelan Equine Encephalitis Virus Vector System

Lee, John S., Pushko, Peter, Parker, Michael D., Dertzbaugh, Mark T., Smith, Leonard A., Smith, Jonathan F.

A candidate vaccine against botulinum neurotoxin serotype A (BoNT/A) was developed by using a Venezuelan equine encephalitis (VEE) virus replicon vector. This vaccine vector is composed of a...

The effect of subunit or modified live bovine herpesvirus-1 vaccines on the efficacy of a recombinant Pasteurella haemolytica vaccine for the prevention of respiratory disease in feedlot calves

Harland, Richard J., Potter, Andrew A., Van Donkersgoed, Joyce, Parker, Michael D., Zamb, Timothy J., ...

The efficacy of a Pasteurella haemolytica vaccine (PhV) administered once to calves within 24 hours of arrival at a feedlot was tested for the ability to prevent morbidity and mortality from all...

Candidate Vaccine against Botulinum Neurotoxin Serotype A Derived from a Venezuelan Equine Encephalitis Virus Vector System

Lee, John S., Pushko, Peter, Parker, Michael D., Dertzbaugh, Mark T., Smith, Leonard A., Smith, Jonathan F.

A candidate vaccine against botulinum neurotoxin serotype A (BoNT/A) was developed by using a Venezuelan equine encephalitis (VEE) virus replicon vector. This vaccine vector is composed of a...

The effect of subunit or modified live bovine herpesvirus-1 vaccines on the efficacy of a recombinant Pasteurella haemolytica vaccine for the prevention of respiratory disease in feedlot calves

Harland, Richard J., Potter, Andrew A., Van Donkersgoed, Joyce, Parker, Michael D., Zamb, Timothy J., ...

The efficacy of a Pasteurella haemolytica vaccine (PhV) administered once to calves within 24 hours of arrival at a feedlot was tested for the ability to prevent morbidity and mortality from all...

Early Events in the Pathogenesis of Eastern Equine Encephalitis Virus in Mice

Vogel, Peter, Kell, Wayne M., Fritz, David L., Parker, Michael D., Schoepp, Randal J.

To elucidate the pathogenesis of eastern equine encephalitis (EEE) virus infections, we used histopathology, immunohistochemistry, and in situ hybridization to track the spread and early cellular...