Lavista-Llanos, Sofía, Centanin, Lázaro, Irisarri, Maximiliano, Russo, Daniela M., Gleadle, Jonathan M., Bocca, Silvia N., ...
In mammalian systems, the heterodimeric basic helix-loop-helix (bHLH)-PAS transcription hypoxia-inducible factor (HIF) has emerged as the key regulator of responses to hypoxia. Here we define a...
Lavista-Llanos, Sofía, Centanin, Lázaro, Irisarri, Maximiliano, Russo, Daniela M., Gleadle, Jonathan M., Bocca, Silvia N., ...
In mammalian systems, the heterodimeric basic helix-loop-helix (bHLH)-PAS transcription hypoxia-inducible factor (HIF) has emerged as the key regulator of responses to hypoxia. Here we define a...
Regulation of the Drosophila Hypoxia-Inducible Factor α Sima by CRM1-Dependent Nuclear Export ▿
Romero, Nuria M., Irisarri, Maximiliano, Roth, Peggy, Cauerhff, Ana, Samakovlis, Christos, Wappner, Pablo
Hypoxia-inducible factor α (HIF-α) proteins are regulated by oxygen levels through several different mechanisms that include protein stability, transcriptional coactivator recruitment, and...