Maura H. Parker

Cell cycle and HEB-mediated regulation of gene expression during myogenic differentiation (2004)

Parker, Maura H

Embryonic studies clearly demonstrate that MyoD and Myf5 are required for specification of the myogenic lineage. Moreover, MyoD plays an essential role in initiating expression of myogenin and...

MyoD Synergizes with the E-Protein HEBβ To Induce Myogenic Differentiation

Parker, Maura H., Perry, Robert L. S., Fauteux, Mélanie C., Berkes, Charlotte A., Rudnicki, Michael A.

The MyoD family of basic helix-loop-helix transcription factors function as heterodimers with members of the E-protein family to induce myogenic gene activation. The E-protein HEB is alternatively...

MyoD Synergizes with the E-Protein HEBβ To Induce Myogenic Differentiation

Parker, Maura H., Perry, Robert L. S., Fauteux, Mélanie C., Berkes, Charlotte A., Rudnicki, Michael A.

The MyoD family of basic helix-loop-helix transcription factors function as heterodimers with members of the E-protein family to induce myogenic gene activation. The E-protein HEB is alternatively...

Rb is required for progression through myogenic differentiation but not maintenance of terminal differentiation

Huh, Michael S., Parker, Maura H., Scimè, Anthony, Parks, Robin, Rudnicki, Michael A.

To investigate the requirement for pRb in myogenic differentiation, a floxed Rb allele was deleted either in proliferating myoblasts or after differentiation. Myf5-Cre mice, lacking pRb in myoblasts,...