Matthias Fischer

Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas (2008)

Westermann, Frank, Muth, Daniel, Benner, Axel, Bauer, Tobias, Henrich, Kai-Oliver, Oberthuer, André, ...

Abstract Background Amplified MYCN oncogene resulting in deregulated MYCN transcriptional activity is observed in 20% of neuroblastomas and identifies a highly aggressive subtype. In MYCN single-copy...

Planar Visibility Counting (2008)

Fischer, Matthias, Hilbig, Matthias, Jähn, Claudius, Ziegler, Martin

For a fixed virtual scene (=collection of simplices) S and given observer position p, how many elements of S are weakly visible (i.e. not fully occluded by others) from p? The present work explores...

Cross-study analysis of gene expression data for intermediate neuroblastoma identifies two biological subtypes (2007)

Warnat, Patrick, Oberthuer, André, Fischer, Matthias, Westermann, Frank, Eils, Roland, Brors, Benedikt

Abstract Background Neuroblastoma patients show heterogeneous clinical courses ranging from life-threatening progression to spontaneous regression. Recently, gene expression profiles of neuroblastoma...

Are Correlations Constant Over Time? (2007)

Fischer, Matthias

A new test for constant correlation is proposed. Based on the bivariate Student-t distribution, this test is derived as Lagrange multiplier (LM) test. Whereas most of the traditional tests (e.g....

Are Correlations Constant Over Time? (2007)

Fischer, Matthias

A new test for constant correlation is proposed. Based on the bivariate Student-t distribution, this test is derived as Lagrange multiplier (LM) test. Whereas most of the traditional tests (e.g....

Elektrische und optische Transportmessungen an einkristallinen organischen Feldeffekt-Transistoren (2007)

Fischer, Matthias

In dieser Arbeit wird der Ladungstransport in organischen Halbleitern untersucht. Es gelang mit Infrarotspektroskopie quasi-freie Ladungsträger bei Raumtemperatur nachzuweisen und Werte für die...

Gene-expression based classification of neuroblastoma patients using a customized oligonucleotide-microarray outperforms current clinical risk stratification (2006)

Oberthuer, André, Berthold, Frank, Warnat, Patrick, Hero, Barbara, Kahlert, Yvonne, Spitz, Rüdiger, ...

PURPOSE: To develop a gene expression–based classifier for neuroblastoma patients that reliably predicts courses of the disease. PATIENTS AND METHODS: Two hundred fifty-one neuroblastoma specimens...

Practice of sedation and analgesia in German intensive care units: results of a national survey (2005)

Martin, Jörg, Parsch, Axel, Franck, Martin, Wernecke, Klaus D, Fischer, Matthias, Spies, Claudia

Abstract Introduction Sedation and analgesia are provided by using different agents and techniques in different countries. The goal is to achieve early spontaneous breathing and to obtain an awake...

Strongly Enhanced Thermal Stability of Crystalline Organic Thin Films Induced by Aluminum Oxide Capping Layers (2004)

Sellner, Stefan, Gerlach, Alexander, Schreiber, Frank, Kelsch, Marion, Kasper, Nikolai, Dosch, Helmut, ...

We show that the thermal stability of thin films of the organic semiconductor diindenoperylene (DIP) can be strongly enhanced by aluminum oxide capping layers. By thermal desorption spectroscopy and...

The fast multipole boundary element method and its application to structure acoustic field interaction (2004)

Fischer, Matthias

The goal of the thesis is to provide an efficient simulation tool for the prediction of sound radiation from vibrating structures. Acoustic simulations are an important step to optimize the...

The fast multipole boundary element method and its application to structure acoustic field interaction (2004)

Fischer, Matthias

The goal of the thesis is to provide an efficient simulation tool for the prediction of sound radiation from vibrating structures. Acoustic simulations are an important step to optimize the...

Lokalisierung eines Gedächtnisses bei Drosophila melanogaster / (2003)

Fischer, Matthias.

Würzburg, Univ., Diss., 2004 (Nicht für den Austausch).

The Randomized Sample Tree: A Data Structure for Interactive (2002)

Jan Klein, Jens Krokowski, Matthias Fischer, Michael Wand, Rolf Wanka

We present a new data structure for rendering highly complex virtual environments of arbitrary topology. The special feature of our approach is that it allows an interactive navigation in very large...

Alcom-FT Technical Report Series (2002)

Jan Klein, Jens Krokowski, Matthias Fischer, Rolf Wanka, Friedhelm Meyer Heide

We present a new algorithm for rendering highly complex 3D scenes of arbitrary topology. The specific feature of our method is that it makes possible an interactive navigation of scenes consisting of...

Bi-directional Coupling of Simulation Tools a with Walkthrough System (2002)

Bengt Mueck, Matthias Fischer, Wilhelm Dangelmaier, Wolfram Klemisch

this paper is the solution of the time synchronisation problem caused by simulation tool and walkthrough system

Randomized Point Sampling for Output-Sensitive Rendering of Complex Dynamic Scenes (2000)

Matthias Fischer

We present a new output-sensitive rendering algorithm, the randomized z-buffer algorithm. It renders an image of a three dimensional scene of triangular primitives by reconstruction from a random...

Randomized Point Sampling for Output-Sensitive Rendering of Complex Dynamic Scenes (2000)

Matthias Fischer

We present a new output-sensitive rendering algorithm, the randomized z-buffer algorithm. It renders an image of a three dimensional scene of triangular primitives by reconstruction from a random...

Partitioned Neighborhood Spanners of Minimal Outdegree (1999)

Matthias Fischer, Martin Ziegler

A geometric spanner with vertex set P ae IR D is a sparse approximation of the complete Euclidean graph determined by P . We introduce the notion of partitioned neighborhood graphs (PNGs), unifying...

Partitioned Neighborhood Spanners of Minimal Outdegree (1999)

Matthias Fischer, Tamas Lukovszki, Martin Ziegler

A geometric spanner with vertex set P ae IR D is a sparse approximation of the complete Euclidean graph determined by P. We introduce the notion of partitioned neighborhood graphs (PNGs), unifying...

Geometric Searching in Walkthrough Animations with Weak Spanners in Real Time (1999)

Matthias Fischer, Martin Ziegler

We study algorithmic aspects in the management of geometric scenes in interactive walkthrough animations. We consider arbitrarily large scenes consisting of unit size balls. For a smooth navigation...

A Network Based Approach for Realtime Walkthrough of Massive Models (1999)

Matthias Fischer, Martin Ziegler

New dynamic search data structures developed recently guarantee constant execution time per search and update, i.e., they fulfil the real-time requirements necessary for interactive walkthrough in...

Partitioned Neighborhood Spanners of Minimal Outdegree (1999)

Matthias Fischer, Tamas Lukovszki, Martin Ziegler

A geometric spanner with vertex set P ae IR D is a sparse approximation of the complete Euclidean graph determined by P. We introduce the notion of partitioned neighborhood graphs (PNGs), unifying...

Partitioned Neighborhood Spanners of Minimal Outdegree (1999)

Matthias Fischer, Martin Ziegler

A geometric spanner with vertex set P ae IR D is a sparse approximation of the complete Euclidean graph determined by P . We introduce the notion of partitioned neighborhood graphs (PNGs), unifying...

Partitioned Neighborhood Spanners of Minimal Outdegree (1999)

Matthias Fischer, Tamas Lukovszki, Martin Ziegler

A geometric spanner with vertex set P ae IR D is a sparse approximation of the complete Euclidean graph determined by P. We introduce the notion of partitioned neighborhood graphs (PNGs), unifying...

Partitioned Neighborhood Spanners of Minimal Outdegree (1999)

Matthias Fischer, Tamas Lukovszki, Martin Ziegler

A geometric spanner with vertex set P ae IR D is a sparse approximation of the complete Euclidean graph determined by P. We introduce the notion of partitioned neighborhood graphs (PNGs), unifying...

A Network Based Approach for Realtime Walkthrough of Massive Models (1998)

Matthias Fischer, Martin Ziegler

New dynamic search data structures developed recently guarantee constant execution time per search and update, i.e., they fulfil the real-time requirements necessary for interactive walkthrough in...

A Network Based Approach for Realtime Walkthrough of Massive Models (1998)

Matthias Fischer, Martin Ziegler

New dynamic search data structures developed recently guarantee constant execution time per search and update, i.e., they fulfil the real-time requirements necessary for interactive walkthrough in...

A Network Based Approach for Realtime Walkthrough of Massive Models (1998)

Matthias Fischer, Martin Ziegler

New dynamic search data structures developed recently guarantee constant execution time per search and update, i.e., they fulfil the real-time requirements necessary for interactive walkthrough in...

Geometric Searching in Walkthrough Animations with Weak Spanners in Real Time (1998)

Matthias Fischer, Martin Ziegler

We study algorithmic aspects in the management of geometric scenes in interactive walkthrough animations. We consider arbitrarily large scenes consisting of unit size balls. For a smooth navigation...

Geometric Searching in Walkthrough Animations with Weak Spanners in Real Time (1998)

Matthias Fischer, Martin Ziegler

We study algorithmic aspects in the management of geometric scenes in interactive walkthrough animations. We consider arbitrarily large scenes consisting of unit size balls. For a smooth navigation...

A Realistic Cost Model for the Communication Time in Parallel Programs on Parallel Computers Using a Service Hardware (1997)

Matthias Fischer, Jochen Rethmann, Alf Wachsmann

In this report, we develop a cost model for the communication time on parallel computers consisting of processors and a service network, i.e., a network performing services like broadcast,...

A Realistic Cost Model for the Communication Time in Parallel Programs (1997)

Matthias Fischer, Jochen Rethmann, Alf Wachsmann

. In this paper we develop a model for communication time on parallel computers consisting of processors and a service network, i.e., a network performing services like broadcast, synchronization,...

A Realistic Cost Model for the Communication Time in Parallel Programs (1997)

Matthias Fischer, Jochen Rethmann, Alf Wachsmann

. In this paper we develop a model for communication time on parallel computers consisting of processors and a service network, i.e., a network performing services like broadcast, synchronization,...

A Realistic Cost Model for the Communication Time in Parallel Programs on Parallel Computers Using a Service Hardware (1997)

Matthias Fischer, Jochen Rethmann, Alf Wachsmann

In this report, we develop a cost model for the communication time on parallel computers consisting of processors and a service network, i.e., a network performing services like broadcast,...

A Realistic Cost Model for the Communication Time in Parallel Programs (1996)

Matthias Fischer, Jochen Rethmann, Alf Wachsmann

. In this paper we develop a model for communication time on parallel computers consisting of processors and a service network, i.e., a network performing services like broadcast, synchronization,...

A single-molecule diode

Elbing, Mark, Ochs, Rolf, Koentopp, Max, Fischer, Matthias, Von Hänisch, Carsten, Weigend, Florian, ...

We have designed and synthesized a molecular rod that consists of two weakly coupled electronic π -systems with mutually shifted energy levels. The asymmetry thus implied manifests itself in a...

Power kurtosis transformations: Definition, properties and ordering

Ingo Klein, Matthias Fischer

Power kurtosis transformation, leptokurtosis, kurtosis ordering, JEL C16, C51,

A single-molecule diode

Elbing, Mark, Ochs, Rolf, Koentopp, Max, Fischer, Matthias, Von Hänisch, Carsten, Weigend, Florian, ...

We have designed and synthesized a molecular rod that consists of two weakly coupled electronic π -systems with mutually shifted energy levels. The asymmetry thus implied manifests itself in a...

Are Correlations Constant Over Time? Application of the CC-TRIGt-test to Return Series from Different Asset Classes.

Matthias Fischer

A new test for constant correlation is proposed. Based on the bivariate Student-t distribution, this test is derived as Lagrange multiplier (LM) test. Whereas most of the traditional tests (e.g....

Reliable Transcript Quantification by Real-Time Reverse Transcriptase-Polymerase Chain Reaction in Primary Neuroblastoma Using Normalization to Averaged Expression Levels of the Control Genes HPRT1 and SDHA

Fischer, Matthias, Skowron, Matthias, Berthold, Frank

Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) represents a sensitive and efficient technique to determine expression levels of target genes in multiple samples and is...