Matthew Booker

A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila (2007)

DasGupta, Ramanuj, Nybakken, Kent, Booker, Matthew, Mathey-Prevot, Bernard, Gonsalves, Foster, Changkakoty, Binita, ...

Abstract Off-target effects have been demonstrated to be a major source of false-positives in RNA interference (RNAi) high-throughput screens. In this study, we re-assess the previously published...

FlyRNAi: the Drosophila RNAi screening center database

Flockhart, Ian, Booker, Matthew, Kiger, Amy, Boutros, Michael, Armknecht, Susan, Ramadan, Nadire, ...

RNA interference (RNAi) has become a powerful tool for genetic screening in Drosophila. At the Drosophila RNAi Screening Center (DRSC), we are using a library of over 21 000 double-stranded RNAs...

FlyRNAi: the Drosophila RNAi screening center database

Flockhart, Ian, Booker, Matthew, Kiger, Amy, Boutros, Michael, Armknecht, Susan, Ramadan, Nadire, ...

RNA interference (RNAi) has become a powerful tool for genetic screening in Drosophila. At the Drosophila RNAi Screening Center (DRSC), we are using a library of over 21 000 double-stranded RNAs...

A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila

DasGupta, Ramanuj, Nybakken, Kent, Booker, Matthew, Mathey-Prevot, Bernard, Gonsalves, Foster, Changkakoty, Binita, ...

A second generation dsRNA library was used to re-assess factors that influence the outcome of transcriptional reporter-based whole-genome RNAi screens for the Wnt/Wingless (wg) and Hedgehog...