Correction: A DNA microarray survey of gene expression in normal human tissues (2005)
Shyamsundar, Radha, Kim, Young H, Higgins, John P, Montgomery, Kelli, Jorden, Michelle, Sethuraman, Anand, ...
No abstract available.
A DNA microarray survey of gene expression in normal human tissues (2005)
Shyamsundar, Radha, Kim, Young H, Higgins, John P, Montgomery, Kelli, Jorden, Michelle, Sethuraman, Anand, ...
Abstract Background Numerous studies have used DNA microarrays to survey gene expression in cancer and other disease states. Comparatively little is known about the genes expressed across the gamut...
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
Perou, Charles M., Jeffrey, Stefanie S., Van De Rijn, Matt, Rees, Christian A., Eisen, Michael B., Ross, Douglas T., ...
cDNA microarrays and a clustering algorithm were used to identify patterns of gene expression in human mammary epithelial cells growing in culture and in primary human breast tumors. Clusters of...
Sørlie, Therese, Perou, Charles M., Tibshirani, Robert, Aas, Turid, Geisler, Stephanie, Johnsen, Hilde, ...
The purpose of this study was to classify breast carcinomas based on variations in gene expression patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical outcome. A...
Diversity of gene expression in adenocarcinoma of the lung
Garber, Mitchell E., Troyanskaya, Olga G., Schluens, Karsten, Petersen, Simone, Thaesler, Zsuzsanna, Pacyna-Gengelbach, Manuela, ...
The global gene expression profiles for 67 human lung tumors representing 56 patients were examined by using 24,000-element cDNA microarrays. Subdivision of the tumors based on gene expression...
Gene Expression Patterns in Human Liver Cancers
Chen, Xin, Cheung, Siu Tim, So, Samuel, Fan, Sheung Tat, Barry, Christopher, Higgins, John, ...
Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. Using cDNA microarrays to characterize patterns of gene expression in HCC, we found consistent differences between the expression...
Diversity, topographic differentiation, and positional memory in human fibroblasts
Chang, Howard Y., Chi, Jen-Tsan, Dudoit, Sandrine, Bondre, Chanda, Van De Rijn, Matt, Botstein, David, ...
A fundamental feature of the architecture and functional design of vertebrate animals is a stroma, composed of extracellular matrix and mesenchymal cells, which provides a structural scaffold and...
Endothelial cell diversity revealed by global expression profiling
Chi, Jen-Tsan, Chang, Howard Y., Haraldsen, Guttorm, Jahnsen, Frode L., Troyanskaya, Olga G., Chang, Dustin S., ...
The vascular system is locally specialized to accommodate widely varying blood flow and pressure and the distinct needs of individual tissues. The endothelial cells (ECs) that line the lumens of...
Gene Expression Patterns in Ovarian Carcinomas
Schaner, Marci E., Ross, Douglas T., Ciaravino, Giuseppe, Sørlie, Therese, Troyanskaya, Olga, Diehn, Maximilian, ...
We used DNA microarrays to characterize the global gene expression patterns in surface epithelial cancers of the ovary. We identified groups of genes that distinguished the clear cell subtype from...
Chang, Howard Y, Sneddon, Julie B, Alizadeh, Ash A, Sood, Ruchira, West, Rob B, Montgomery, Kelli, ...
Cancer invasion and metastasis have been likened to wound healing gone awry. Despite parallels in cellular behavior between cancer progression and wound healing, the molecular relationships between...
Gene expression profiling identifies clinically relevant subtypes of prostate cancer
Lapointe, Jacques, Li, Chunde, Higgins, John P., Van De Rijn, Matt, Bair, Eric, Montgomery, Kelli, ...
Prostate cancer, a leading cause of cancer death, displays a broad range of clinical behavior from relatively indolent to aggressive metastatic disease. To explore potential molecular variation...
Gene Expression in the Normal Adult Human Kidney Assessed by Complementary DNA Microarray
Higgins, John P.T., Wang, Lingli, Kambham, Neeraja, Montgomery, Kelli, Mason, Veronica, Vogelmann, Stefanie U., ...
The kidney is a highly specialized organ with a complex, stereotyped architecture and a great diversity of functions and cell types. Because the microscopic organization of the nephron, the...
A DNA microarray survey of gene expression in normal human tissues
Shyamsundar, Radha, Kim, Young H, Higgins, John P, Montgomery, Kelli, Jorden, Michelle, Sethuraman, Anand, ...
A systematic survey of gene expression in 115 human tissue samples using cDNA microarrays provides a dataset that can be used as a baseline for comparison with expression in diseased tissue.
Determination of Stromal Signatures in Breast Carcinoma
West, Robert B, Nuyten, Dimitry S. A, Subramanian, Subbaya, Nielsen, Torsten O, Corless, Christopher L, Rubin, Brian P, ...
Many soft tissue tumors recapitulate features of normal connective tissue. We hypothesize that different types of fibroblastic tumors are representative of different populations of fibroblastic cells...
Correction: A DNA microarray survey of gene expression in normal human tissues
Shyamsundar, Radha, Kim, Young H, Higgins, John P, Montgomery, Kelli, Jorden, Michelle, Sethuraman, Anand, ...
A correction to A DNA microarray survey of gene expression in normal human tissues by R Shyamsundar, YH Kim, JP Higgins, K Montgomery, M Jorden, A Sethuraman, M van de Rijn, D Botstein, PO Brown and...
West, Robert B., Rubin, Brian P., Miller, Melinda A., Subramanian, Subbaya, Kaygusuz, Gulsah, Montgomery, Kelli, ...
Tenosynovial giant-cell tumor (TGCT) and pigmented villonodular synovitis (PVNS) are related conditions with features of both reactive inflammatory disorders and clonal neoplastic proliferations....
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
Perou, Charles M., Jeffrey, Stefanie S., Van De Rijn, Matt, Rees, Christian A., Eisen, Michael B., Ross, Douglas T., ...
cDNA microarrays and a clustering algorithm were used to identify patterns of gene expression in human mammary epithelial cells growing in culture and in primary human breast tumors. Clusters of...
Sørlie, Therese, Perou, Charles M., Tibshirani, Robert, Aas, Turid, Geisler, Stephanie, Johnsen, Hilde, ...
The purpose of this study was to classify breast carcinomas based on variations in gene expression patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical outcome. A...
Diversity of gene expression in adenocarcinoma of the lung
Garber, Mitchell E., Troyanskaya, Olga G., Schluens, Karsten, Petersen, Simone, Thaesler, Zsuzsanna, Pacyna-Gengelbach, Manuela, ...
The global gene expression profiles for 67 human lung tumors representing 56 patients were examined by using 24,000-element cDNA microarrays. Subdivision of the tumors based on gene expression...
Gene Expression Patterns in Human Liver Cancers
Chen, Xin, Cheung, Siu Tim, So, Samuel, Fan, Sheung Tat, Barry, Christopher, Higgins, John, ...
Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. Using cDNA microarrays to characterize patterns of gene expression in HCC, we found consistent differences between the expression...
Diversity, topographic differentiation, and positional memory in human fibroblasts
Chang, Howard Y., Chi, Jen-Tsan, Dudoit, Sandrine, Bondre, Chanda, Van De Rijn, Matt, Botstein, David, ...
A fundamental feature of the architecture and functional design of vertebrate animals is a stroma, composed of extracellular matrix and mesenchymal cells, which provides a structural scaffold and...
Endothelial cell diversity revealed by global expression profiling
Chi, Jen-Tsan, Chang, Howard Y., Haraldsen, Guttorm, Jahnsen, Frode L., Troyanskaya, Olga G., Chang, Dustin S., ...
The vascular system is locally specialized to accommodate widely varying blood flow and pressure and the distinct needs of individual tissues. The endothelial cells (ECs) that line the lumens of...
Gene Expression Patterns in Ovarian Carcinomas
Schaner, Marci E., Ross, Douglas T., Ciaravino, Giuseppe, Sørlie, Therese, Troyanskaya, Olga, Diehn, Maximilian, ...
We used DNA microarrays to characterize the global gene expression patterns in surface epithelial cancers of the ovary. We identified groups of genes that distinguished the clear cell subtype from...
Chang, Howard Y, Sneddon, Julie B, Alizadeh, Ash A, Sood, Ruchira, West, Rob B, Montgomery, Kelli, ...
Cancer invasion and metastasis have been likened to wound healing gone awry. Despite parallels in cellular behavior between cancer progression and wound healing, the molecular relationships between...
Gene expression profiling identifies clinically relevant subtypes of prostate cancer
Lapointe, Jacques, Li, Chunde, Higgins, John P., Van De Rijn, Matt, Bair, Eric, Montgomery, Kelli, ...
Prostate cancer, a leading cause of cancer death, displays a broad range of clinical behavior from relatively indolent to aggressive metastatic disease. To explore potential molecular variation...
Gene Expression in the Normal Adult Human Kidney Assessed by Complementary DNA Microarray
Higgins, John P.T., Wang, Lingli, Kambham, Neeraja, Montgomery, Kelli, Mason, Veronica, Vogelmann, Stefanie U., ...
The kidney is a highly specialized organ with a complex, stereotyped architecture and a great diversity of functions and cell types. Because the microscopic organization of the nephron, the...
Chang, Howard Y., Nuyten, Dimitry S. A., Sneddon, Julie B., Hastie, Trevor, Tibshirani, Robert, Sørlie, Therese, ...
Based on the hypothesis that features of the molecular program of normal wound healing might play an important role in cancer metastasis, we previously identified consistent features in the...
A DNA microarray survey of gene expression in normal human tissues
Shyamsundar, Radha, Kim, Young H, Higgins, John P, Montgomery, Kelli, Jorden, Michelle, Sethuraman, Anand, ...
A systematic survey of gene expression in 115 human tissue samples using cDNA microarrays provides a dataset that can be used as a baseline for comparison with expression in diseased tissue.
Determination of Stromal Signatures in Breast Carcinoma
West, Robert B, Nuyten, Dimitry S. A, Subramanian, Subbaya, Nielsen, Torsten O, Corless, Christopher L, Rubin, Brian P, ...
Many soft tissue tumors recapitulate features of normal connective tissue. We hypothesize that different types of fibroblastic tumors are representative of different populations of fibroblastic cells...
Correction: A DNA microarray survey of gene expression in normal human tissues
Shyamsundar, Radha, Kim, Young H, Higgins, John P, Montgomery, Kelli, Jorden, Michelle, Sethuraman, Anand, ...
A correction to A DNA microarray survey of gene expression in normal human tissues by R Shyamsundar, YH Kim, JP Higgins, K Montgomery, M Jorden, A Sethuraman, M van de Rijn, D Botstein, PO Brown and...
West, Robert B., Rubin, Brian P., Miller, Melinda A., Subramanian, Subbaya, Kaygusuz, Gulsah, Montgomery, Kelli, ...
Tenosynovial giant-cell tumor (TGCT) and pigmented villonodular synovitis (PVNS) are related conditions with features of both reactive inflammatory disorders and clonal neoplastic proliferations....
West, Robert B., Corless, Christopher L., Chen, Xin, Rubin, Brian P., Subramanian, Subbaya, Montgomery, Kelli, ...
We recently characterized gene expression patterns in gastrointestinal stromal tumors (GISTs) using cDNA microarrays, and found that the gene FLJ10261 (DOG1, discovered on GIST-1), encoding a...
Gene Expression Patterns in Pancreatic Tumors, Cells and Tissues
Lowe, Anson W., Olsen, Mari, Hao, Ying, Lee, Sum P., Taek Lee, Kyu, Chen, Xin, ...
Sneddon, Julie B., Zhen, Hanson H., Montgomery, Kelli, Van De Rijn, Matt, Tward, Aaron D., West, Robert, ...
Although tissue microenvironments play critical roles in epithelial development and tumorigenesis, the factors mediating these effects are poorly understood. In this work, we used a genomic approach...
Liu, Chih Long, Prapong, Wijan, Natkunam, Yasodha, Alizadeh, Ash, Montgomery, Kelli, Gilks, C. Blake, ...
The creation of tissue microarrays (TMAs) allows for the rapid immunohistochemical analysis of thousands of tissue samples, with numerous different antibodies per sample. This technical development...
Van De Rijn, Matt, Perou, Charles M., Tibshirani, Rob, Haas, Phillippe, Kallioniemi, Olli, Kononen, Juha, ...
While several prognostic factors have been identified in breast carcinoma, the clinical outcome remains hard to predict for individual patients. Better predictive markers are needed to help guide...
Gene Expression Patterns in Renal Cell Carcinoma Assessed by Complementary DNA Microarray
Higgins, John P.T., Shinghal, Rajesh, Gill, Harcharan, Reese, Jeffrey H., Terris, Martha, Cohen, Ronald J., ...
Renal cell carcinoma comprises several histological types with different clinical behavior. Accurate pathological characterization is important in the clinical management of these tumors. We describe...
Nielsen, Torsten O., Hsu, Forrest D., O’Connell, John X., Gilks, C. Blake, Sorensen, Poul H.B., Linn, Sabine, ...
Histological diagnosis of synovial sarcoma can be difficult. Genome-wide expression profiling has identified a number of genes expressed at higher levels in synovial sarcoma than in other soft tissue...
Gene Expression Patterns and Gene Copy Number Changes in Dermatofibrosarcoma Protuberans
Linn, Sabine C., West, Rob B., Pollack, Jonathan R., Zhu, Shirley, Hernandez-Boussard, Tina, Nielsen, Torsten O., ...
Dermatofibrosarcoma protuberans (DFSP) is an aggressive spindle cell neoplasm. It is associated with the chromosomal translocation, t(17:22), which fuses the COL1A1 and PDGFβ genes. We determined...
Chi, Jen-Tsan, Rodriguez, Edwin H, Wang, Zhen, Nuyten, Dimitry S. A, Mukherjee, Sayan, Van De Rijn, Matt, ...
Smooth muscle is present in a wide variety of anatomical locations, such as blood vessels, various visceral organs, and hair follicles. Contraction of smooth muscle is central to functions as diverse...
Lehman, Norman L., Tibshirani, Rob, Hsu, Jerry Y., Natkunam, Yasodha, Harris, Brent T., West, Robert B., ...
The fidelity of cell division is dependent on the accumulation and ordered destruction of critical protein regulators. By triggering the appropriately timed, ubiquitin-dependent proteolysis of the...
The Stanford Tissue Microarray Database
Marinelli, Robert J., Montgomery, Kelli, Liu, Chih Long, Shah, Nigam H., Prapong, Wijan, Nitzberg, Michael, ...
The Stanford Tissue Microarray Database (TMAD; http://tma.stanford.edu) is a public resource for disseminating annotated tissue images and associated expression data. Stanford University...
Genomic Profiling Identifies GATA6 as a Candidate Oncogene Amplified in Pancreatobiliary Cancer
Kwei, Kevin A., Bashyam, Murali D., Kao, Jessica, Ratheesh, Raman, Reddy, Edumakanti C., Kim, Young H., ...
Pancreatobiliary cancers have among the highest mortality rates of any cancer type. Discovering the full spectrum of molecular genetic alterations may suggest new avenues for therapy. To catalogue...