Norrander, Jan M., DeCathelineau, Aimee M., Brown, Jennifer A., Porter, Mary E., Linck, Richard W.
Ciliary and flagellar microtubules contain a specialized set of three protofilaments, termed ribbons, that are composed of tubulin and several associated proteins. Previous studies of sea urchin...
Perrone, Catherine A., Myster, Steven H., Bower, Raqual, O'Toole, Eileen T., Porter, Mary E.
To identify domains in the dynein heavy chain (Dhc) required for the assembly of an inner arm dynein, we characterized a new motility mutant (ida2-6) obtained by insertional mutagenesis. ida2-6...
Cytoplasmic Dynein Heavy Chain 1b Is Required for Flagellar Assembly in Chlamydomonas
Porter, Mary E., Bower, Raqual, Knott, Julie A., Byrd, Pamela, Dentler, William
A second cytoplasmic dynein heavy chain (cDhc) has recently been identified in several organisms, and its expression pattern is consistent with a possible role in axoneme assembly. We have used a...
Perrone, Catherine A., Yang, Pinfen, O’Toole, Eileen, Sale, Winfield S., Porter, Mary E.
To identify new loci that are involved in the assembly and targeting of dynein complexes, we have screened a collection of motility mutants that were generated by insertional mutagenesis. One such...
Rupp, Gerald, O'Toole, Eileen, Porter, Mary E.
Efficient motility of the eukaryotic flagellum requires precise temporal and spatial control of its constituent dynein motors. The central pair and its associated structures have been implicated as...
Perrone, Catherine A., Tritschler, Douglas, Taulman, Patrick, Bower, Raqual, Yoder, Bradley K., Porter, Mary E.
The assembly of cilia and flagella depends on bidirectional intraflagellar transport (IFT). Anterograde IFT is driven by kinesin II, whereas retrograde IFT requires cytoplasmic dynein 1b (cDHC1b)....
Hendrickson, Triscia W., Perrone, Catherine A., Griffin, Paul, Wuichet, Kristin, Mueller, Joshua, Yang, Pinfen, ...
Increased phosphorylation of dynein IC IC138 correlates with decreases in flagellar microtubule sliding and phototaxis defects. To test the hypothesis that regulation of IC138 phosphorylation...
Mueller, Joshua, Perrone, Catherine A., Bower, Raqual, Cole, Douglas G., Porter, Mary E.
Intraflagellar transport (IFT) is a bidirectional process required for assembly and maintenance of cilia and flagella. Kinesin-2 is the anterograde IFT motor, and Dhc1b/Dhc2 drives retrograde IFT. To...
Norrander, Jan M., DeCathelineau, Aimee M., Brown, Jennifer A., Porter, Mary E., Linck, Richard W.
Ciliary and flagellar microtubules contain a specialized set of three protofilaments, termed ribbons, that are composed of tubulin and several associated proteins. Previous studies of sea urchin...
Perrone, Catherine A., Myster, Steven H., Bower, Raqual, O'Toole, Eileen T., Porter, Mary E.
To identify domains in the dynein heavy chain (Dhc) required for the assembly of an inner arm dynein, we characterized a new motility mutant (ida2-6) obtained by insertional mutagenesis. ida2-6...
Cytoplasmic Dynein Heavy Chain 1b Is Required for Flagellar Assembly in Chlamydomonas
Porter, Mary E., Bower, Raqual, Knott, Julie A., Byrd, Pamela, Dentler, William
A second cytoplasmic dynein heavy chain (cDhc) has recently been identified in several organisms, and its expression pattern is consistent with a possible role in axoneme assembly. We have used a...
Perrone, Catherine A., Yang, Pinfen, O’Toole, Eileen, Sale, Winfield S., Porter, Mary E.
To identify new loci that are involved in the assembly and targeting of dynein complexes, we have screened a collection of motility mutants that were generated by insertional mutagenesis. One such...
Rupp, Gerald, O'Toole, Eileen, Porter, Mary E.
Efficient motility of the eukaryotic flagellum requires precise temporal and spatial control of its constituent dynein motors. The central pair and its associated structures have been implicated as...
Perrone, Catherine A., Tritschler, Douglas, Taulman, Patrick, Bower, Raqual, Yoder, Bradley K., Porter, Mary E.
The assembly of cilia and flagella depends on bidirectional intraflagellar transport (IFT). Anterograde IFT is driven by kinesin II, whereas retrograde IFT requires cytoplasmic dynein 1b (cDHC1b)....
Hendrickson, Triscia W., Perrone, Catherine A., Griffin, Paul, Wuichet, Kristin, Mueller, Joshua, Yang, Pinfen, ...
Increased phosphorylation of dynein IC IC138 correlates with decreases in flagellar microtubule sliding and phototaxis defects. To test the hypothesis that regulation of IC138 phosphorylation...
Mueller, Joshua, Perrone, Catherine A., Bower, Raqual, Cole, Douglas G., Porter, Mary E.
Intraflagellar transport (IFT) is a bidirectional process required for assembly and maintenance of cilia and flagella. Kinesin-2 is the anterograde IFT motor, and Dhc1b/Dhc2 drives retrograde IFT. To...
Cytoplasmic dynein nomenclature
Pfister, K. Kevin, Fisher, Elizabeth M.C., Gibbons, Ian R., Hays, Thomas S., Holzbaur, Erika L.F., McIntosh, J. Richard, ...
A variety of names has been used in the literature for the subunits of cytoplasmic dynein complexes. Thus, there is a strong need for a more definitive consensus statement on nomenclature. This is...
Myster, Steven H., Knott, Julie A., Wysocki, Katrina M., O'Toole, Eileen, Porter, Mary E.
Flagellar motility is generated by the activity of multiple dynein motors, but the specific role of each dynein heavy chain (Dhc) is largely unknown, and the mechanism by which the different Dhcs are...
The dynein regulatory complex (DRC) is an important intermediate in the pathway that regulates flagellar motility. To identify subunits of the DRC, we characterized a Chlamydomonas motility mutant...