Martin Hirst

Transcriptome analysis for Caenorhabditis elegansbased on novel expressed sequence tags (2008)

Shin, Heesun, Hirst, Martin, Bainbridge, Matthew N, Magrini, Vincent, Mardis, Elaine, Moerman, Donald G, ...

Abstract Background We have applied a high-throughput pyrosequencing technology for transcriptome profiling of Caenorhabditis elegans in its first larval stage. Using this approach, we have generated...

Dynamic Remodeling of Individual Nucleosomes Across a Eukaryotic Genome in Response to Transcriptional Perturbation (2008)

Sushma Shivaswamy, Akshay Bhinge, Yongjun Zhao, Steven Jones, Martin Hirst, Vishwanath R. Iyer

The eukaryotic genome is packaged as chromatin with nucleosomes comprising its basic structural unit, but the detailed structure of chromatin and its dynamic remodeling in terms of individual...

LongSAGE profiling of nine human embryonic stem cell lines (2007)

Hirst, Martin, Delaney, Allen, Rogers, Sean A, Schnerch, Angelique, Persaud, Deryck R, O'Connor, Michael D, ...

Abstract To facilitate discovery of novel human embryonic stem cell (ESC) transcripts, we generated 2.5 million LongSAGE tags from 9 human ESC lines. Analysis of this data revealed that ESCs express...

Novel expressed sequences identified in a model of androgen independent prostate cancer (2007)

Quayle, Steven N, Hare, Heidi, Delaney, Allen D, Hirst, Martin, Hwang, Dorothy, Schein, Jacqueline E, ...

Abstract Background Prostate cancer is the most frequently diagnosed cancer in American men, and few effective treatment options are available to patients who develop hormone-refractory prostate...

Analysis of the prostate cancer cell line LNCaP transcriptome using a sequencing-by-synthesis approach (2006)

Bainbridge, Matthew N, Warren, René L, Hirst, Martin, Romanuik, Tammy, Zeng, Thomas, Go, Anne, ...

Abstract Background High throughput sequencing-by-synthesis is an emerging technology that allows the rapid production of millions of bases of data. Although the sequence reads are short, they can...

What is Gonzo? The Etymology of an Urban Legend (2004)

Hirst, Martin

The delightfully enigmatic and poetic 'gonzo' has come a long way from its humble origins as a throw-away line in the introduction to an off-beat story about the classic American road trip of...

Newspace: A Place, Not Just A Platform, For A Critical Pedagogy Of Journalism (2004)

Harrison, John, Hirst, Martin, De Wall, Michael

The traditional approach to curriculum development in journalism practice has been the simulation model. Identify what 'real' newsrooms do and emulate it. The approach presented here both inverts and...

Getting the Story Straight: Greg Sheridan in the Shifting Moral Sands of Iraq (2004)

Hirst, Martin, Schutze, Robert

This essay traces the evolution of Greg Sheridan's public statements on international affairs since September 11, 2001, finding coherence in the moral epistemology that underpins his arguments. In a...

Allies Down Under? The Australian at War and the "Big Lie" (2004)

Hirst, Martin, Schutze, Robert

There can be no doubt that the Murdoch press played an important role in cohering what support there was for Australia's involvement in 'Gulf War Two'. From the start, Murdoch's 'Australian'...

Allies Down Under? The Australian at War and the "Big Lie" (2004)

Hirst, Martin, Schutze, Robert, Berenger, Ralph D.

There can be no doubt that the Murdoch press played an important role in cohering what support there was for Australia's involvement in 'Gulf War Two'. From the start, Murdoch's 'Australian'...

Getting the Story Straight: Greg Sheridan in the Shifting Moral Sands of Iraq (2004)

Hirst, Martin, Schutze, Robert

This essay traces the evolution of Greg Sheridan's public statements on international affairs since September 11, 2001, finding coherence in the moral epistemology that underpins his arguments. In a...

Newspace: A Place, Not Just A Platform, For A Critical Pedagogy Of Journalism (2004)

Harrison, John, Hirst, Martin, De Wall, Michael

The traditional approach to curriculum development in journalism practice has been the simulation model. Identify what 'real' newsrooms do and emulate it. The approach presented here both inverts and...

What is Gonzo? The Etymology of an Urban Legend (2004)

Hirst, Martin

The delightfully enigmatic and poetic 'gonzo' has come a long way from its humble origins as a throw-away line in the introduction to an off-beat story about the classic American road trip of...

What is Gonzo? The Etymology of an Urban Legend (2004)

Hirst, Martin

The delightfully enigmatic and poetic 'gonzo' has come a long way from its humble origins as a throw-away line in the introduction to an off-beat story about the classic American road trip of...

Newspace: A Place, Not Just A Platform, For A Critical Pedagogy Of Journalism (2004)

Harrison, John, Hirst, Martin, De Wall, Michael

The traditional approach to curriculum development in journalism practice has been the simulation model. Identify what 'real' newsrooms do and emulate it. The approach presented here both inverts and...

Allies Down Under? The Australian at War and the "Big Lie" (2004)

Hirst, Martin, Schutze, Robert

There can be no doubt that the Murdoch press played an important role in cohering what support there was for Australia's involvement in 'Gulf War Two'. From the start, Murdoch's 'Australian'...

Getting the Story Straight: Greg Sheridan in the Shifting Moral Sands of Iraq (2004)

Hirst, Martin, Schutze, Robert

This essay traces the evolution of Greg Sheridan's public statements on international affairs since September 11, 2001, finding coherence in the moral epistemology that underpins his arguments. In a...

Afghanistan? Somewhere west of India, isn't it? (2003)

Patching, Roger M., Hirst, Martin

For more than 10 years, the senior co-author has been regularly testing tertiary journalism students on their 'news geography' - the ability to accurately locate on a world map 10 countries that had...

Afghanistan? Somewhere west of India, isn't it? (2003)

Patching, Roger M., Hirst, Martin

For more than 10 years, the senior co-author has been regularly testing tertiary journalism students on their 'news geography' - the ability to accurately locate on a world map 10 countries that had...

Allies Down Under? The Australian at war (2003)

Hirst, Martin

There can be no doubt that the Murdoch press played an important role in cohering what support there was for Australia's involvement in 'Gulf War Two'. From the start, Murdoch's 'Australian'...

Allies Down Under? The Australian at war (2003)

Hirst, Martin, Kumar, Amitava, Ryan, Michael

There can be no doubt that the Murdoch press played an important role in cohering what support there was for Australia's involvement in 'Gulf War Two'. From the start, Murdoch's 'Australian'...

Allies Down Under? The Australian at war (2003)

Hirst, Martin

There can be no doubt that the Murdoch press played an important role in cohering what support there was for Australia's involvement in 'Gulf War Two'. From the start, Murdoch's 'Australian'...

Afghanistan? Somewhere west of India, isn't it? (2003)

Patching, Roger M., Hirst, Martin

For more than 10 years, the senior co-author has been regularly testing tertiary journalism students on their 'news geography' - the ability to accurately locate on a world map 10 countries that had...

Grey Collar Journalism: The Social Relations of News Production (2002)

Hirst, Martin

"On any meaningful notion of 'class' as a concept related to the social relations deriving from the system of production in a Capitalist society like ours, journalists are not 'middle class' ... they...

Grey Collar Journalism: The Social Relations of News Production (2002)

Hirst, Martin

"On any meaningful notion of 'class' as a concept related to the social relations deriving from the system of production in a Capitalist society like ours, journalists are not 'middle class' ... they...

Ethics in Journalism and Cheryl Kernot: A Colloquium (2002)

Breit, Rhonda, Harrison, John, Hirst, Martin, McLellan, Trina, Bartlett, Desley

Ethics asks the 'ought' question. Ought Laurie Oakes have disclosed Cheryl Kernot's affair with Gareth Evans? Ought the affair be taken into account in any assessment of Kernot's motives for...

Grey Collar Journalism: The Social Relations of News Production (2002)

Hirst, Martin

"On any meaningful notion of 'class' as a concept related to the social relations deriving from the system of production in a Capitalist society like ours, journalists are not 'middle class' ... they...

Grey Collar Journalism: The Social Relations of News Production (2002)

Hirst, Martin

"On any meaningful notion of 'class' as a concept related to the social relations deriving from the system of production in a Capitalist society like ours, journalists are not 'middle class' ... they...

The 1997 top ten survey: students' views of what makes news (1998)

Patching, Roger M., Hirst, Martin

Have you ever wondered how journalism students learn to differentiate the 'important' story from the daily dross that journalism inevitably throws up? We have. This paper examines the choices...

The 1997 top ten survey: students' views of what makes news (1998)

Patching, Roger M., Hirst, Martin

Have you ever wondered how journalism students learn to differentiate the 'important' story from the daily dross that journalism inevitably throws up? We have. This paper examines the choices...

The 1997 top ten survey: students' views of what makes news (1998)

Patching, Roger M., Hirst, Martin

Have you ever wondered how journalism students learn to differentiate the 'important' story from the daily dross that journalism inevitably throws up? We have. This paper examines the choices...

Across The Genres: How Journalism Is Changing In The 1990s (1996)

Guerke, Lani, Hirst, Martin

Writing is the key element in the dissemination of information. Content is king, whether for online, radio, print, or multimedia journalism. Increasingly converging production and delivery...

Across The Genres: How Journalism Is Changing In The 1990s (1996)

Guerke, Lani, Hirst, Martin

Writing is the key element in the dissemination of information. Content is king, whether for online, radio, print, or multimedia journalism. Increasingly converging production and delivery...

When Too Much Entertainment Is Barely Enough: Current Affairs Television In The 1990s (1995)

Hirst, Martin, White, Tiffany, Chaplin, David, Wilson, Justine

The article examines the state of current affairs journalism and looks at news values versus entertainment values.

When Too Much Entertainment Is Barely Enough: Current Affairs Television In The 1990s (1995)

Hirst, Martin, White, Tiffany, Chaplin, David, Wilson, Justine

The article examines the state of current affairs journalism and looks at news values versus entertainment values.

A two-hybrid system for transactivator bait proteins

Hirst, Martin, Ho, Cynthia, Sabourin, Luc, Rudnicki, Michael, Penn, Linda, Sadowski, Ivan

We describe a two-hybrid strategy for detection of interactions with transactivator proteins. This repressed transactivator (RTA) system employs the N-terminal repression domain of the yeast general...

Naturally Occurring Human Immunodeficiency Virus Type 1 Long Terminal Repeats Have a Frequently Observed Duplication That Binds RBF-2 and Represses Transcription

Estable, Mario Clemente, Bell, Brendan, Hirst, Martin, Sadowski, Ivan

Approximately 38% of human immunodeficiency virus type 1 (HIV-1)-infected patients within the Vancouver Lymphadenopathy-AIDS Study have proviruses bearing partial 15- to 34-nucleotide duplications...

Isolation and identification of L-dopa decarboxylase as a protein that binds to and enhances transcriptional activity of the androgen receptor using the repressed transactivator yeast two-hybrid system.

Wafa, Latif A, Cheng, Helen, Rao, Mira A, Nelson, Colleen C, Cox, Michael, Hirst, Martin, ...

The AR (androgen receptor) is a ligand-regulated transcription factor, which belongs to the steroid receptor family and plays an essential role in growth and development of the prostate....

A mouse atlas of gene expression: Large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells

Siddiqui, Asim S., Khattra, Jaswinder, Delaney, Allen D., Zhao, Yongjun, Astell, Caroline, Asano, Jennifer, ...

We analyzed 8.55 million LongSAGE tags generated from 72 libraries. Each LongSAGE library was prepared from a different mouse tissue. Analysis of the data revealed extensive overlap with existing...

Global Media Goes To War: Role of News and Entertainment Media During the 2003 Iraq War

Hirst, Martin, Schutze, Robert

There can be no doubt that the Murdoch press played an important role in cohering what support there was for Australia's involvement in 'Gulf War Two'. From the start, Murdoch's 'Australian'...

A two-hybrid system for transactivator bait proteins

Hirst, Martin, Ho, Cynthia, Sabourin, Luc, Rudnicki, Michael, Penn, Linda, Sadowski, Ivan

We describe a two-hybrid strategy for detection of interactions with transactivator proteins. This repressed transactivator (RTA) system employs the N-terminal repression domain of the yeast general...

Naturally Occurring Human Immunodeficiency Virus Type 1 Long Terminal Repeats Have a Frequently Observed Duplication That Binds RBF-2 and Represses Transcription

Estable, Mario Clemente, Bell, Brendan, Hirst, Martin, Sadowski, Ivan

Approximately 38% of human immunodeficiency virus type 1 (HIV-1)-infected patients within the Vancouver Lymphadenopathy-AIDS Study have proviruses bearing partial 15- to 34-nucleotide duplications...

Isolation and identification of L-dopa decarboxylase as a protein that binds to and enhances transcriptional activity of the androgen receptor using the repressed transactivator yeast two-hybrid system.

Wafa, Latif A, Cheng, Helen, Rao, Mira A, Nelson, Colleen C, Cox, Michael, Hirst, Martin, ...

The AR (androgen receptor) is a ligand-regulated transcription factor, which belongs to the steroid receptor family and plays an essential role in growth and development of the prostate....

A mouse atlas of gene expression: Large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells

Siddiqui, Asim S., Khattra, Jaswinder, Delaney, Allen D., Zhao, Yongjun, Astell, Caroline, Asano, Jennifer, ...

We analyzed 8.55 million LongSAGE tags generated from 72 libraries. Each LongSAGE library was prepared from a different mouse tissue. Analysis of the data revealed extensive overlap with existing...

Across The Genres: How Journalism Is Changing In The 1990s

Guerke, Lani, Hirst, Martin

Writing is the key element in the dissemination of information. Content is king, whether for online, radio, print, or multimedia journalism. Increasingly converging production and delivery...

When Too Much Entertainment Is Barely Enough: Current Affairs Television In The 1990s

Hirst, Martin, White, Tiffany, Chaplin, David, Wilson, Justine

The article examines the state of current affairs journalism and looks at news values versus entertainment values.

Ethics in Journalism and Cheryl Kernot: A Colloquium

Breit, Rhonda, Harrison, John, Hirst, Martin, McLellan, Trina, Bartlett, Desley

Ethics asks the 'ought' question. Ought Laurie Oakes have disclosed Cheryl Kernot's affair with Gareth Evans? Ought the affair be taken into account in any assessment of Kernot's motives for...

Global Media Goes To War: Role of News and Entertainment Media During the 2003 Iraq War

Hirst, Martin, Schutze, Robert

There can be no doubt that the Murdoch press played an important role in cohering what support there was for Australia's involvement in 'Gulf War Two'. From the start, Murdoch's 'Australian'...

Large-scale production of SAGE libraries from microdissected tissues, flow-sorted cells, and cell lines

Khattra, Jaswinder, Delaney, Allen D., Zhao, Yongjun, Siddiqui, Asim, Asano, Jennifer, McDonald, Helen, ...

We describe the details of a serial analysis of gene expression (SAGE) library construction and analysis platform that has enabled the generation of >298 high-quality SAGE libraries and >30 million...

Dynamic Remodeling of Individual Nucleosomes Across a Eukaryotic Genome in Response to Transcriptional Perturbation

Shivaswamy, Sushma, Bhinge, Akshay, Zhao, Yongjun, Jones, Steven, Hirst, Martin, Iyer, Vishwanath R

The eukaryotic genome is packaged as chromatin with nucleosomes comprising its basic structural unit, but the detailed structure of chromatin and its dynamic remodeling in terms of individual...

Global Media Goes To War: Role of News and Entertainment Media During the 2003 Iraq War

Hirst, Martin, Schutze, Robert

There can be no doubt that the Murdoch press played an important role in cohering what support there was for Australia's involvement in 'Gulf War Two'. From the start, Murdoch's 'Australian'...

LongSAGE profiling of nine human embryonic stem cell lines

Hirst, Martin, Delaney, Allen, Rogers, Sean A, Schnerch, Angelique, Persaud, Deryck R, O'Connor, Michael D, ...

Analysis of a 2.6 million longSAGE sequence tag resource generated from nine human embryonic stem cell lines reveals an enrichment of RNA binding proteins and novel ES-specific transcripts.

Global analysis of in vivo Foxa2-binding sites in mouse adult liver using massively parallel sequencing

Wederell, Elizabeth D., Bilenky, Mikhail, Cullum, Rebecca, Thiessen, Nina, Dagpinar, Melis, Delaney, Allen, ...

Foxa2 (HNF3β) is a one of three, closely related transcription factors that are critical to the development and function of the mouse liver. We have used chromatin immunoprecipitation and massively...

Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells

Morin, Ryan D., O’Connor, Michael D., Griffith, Malachi, Kuchenbauer, Florian, Delaney, Allen, Prabhu, Anna-Liisa, ...

MicroRNAs (miRNAs) are emerging as important, albeit poorly characterized, regulators of biological processes. Key to further elucidation of their roles is the generation of more complete lists of...