Reductive stress on life span extension in C. elegans (2008)
Ralser, Markus, Benjamin, Ivor J
Abstract Recently, Schulz and colleagues have contributed to the ongoing controversy on the unproven role of oxidative stress in the aging process in their well-performed study 'Glucose restriction...
Ralser, Markus, Nebel, Almut, Kleindorp, Rabea, Krobitsch, Sylvia, Lehrach, Hans, Schreiber, Stefan, ...
Abstract Background Triosephosphate isomerase (TPI) is a central and conserved glycolytic enzyme. In humans, TPI is encoded by a single gene on 12p13, and associated with a rare genetic disorder, TPI...
Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress (2007)
Ralser, Markus, Wamelink, Mirjam M, Kowald, Axel, Gerisch, Birgit, Heeren, Gino, Struys, Eduard A, ...
Abstract Background Eukaryotic cells have evolved various response mechanisms to counteract the deleterious consequences of oxidative stress. Among these processes, metabolic alterations seem to play...
Nonhoff, Ute, Ralser, Markus, Welzel, Franziska, Piccini, Ilaria, Balzereit, Daniela, Yaspo, Marie-Laure, ...
Tight control of translation is fundamental for eukaryotic cells, and deregulation of proteins implicated contributes to numerous human diseases. The neurodegenerative disorder spinocerebellar ataxia...
Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress (2007)
Ralser, Markus, Wamelink, Mirjam M., Kowald, Axel, Gerisch, Birgit, Heeren, Gino, Struys, Eduard A., ...
Background Eukaryotic cells have evolved various response mechanisms to counteract the deleterious consequences of oxidative stress. Among these processes, metabolic alterations seem to play an...
Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress (2007)
Ralser, Markus, Wamelink, Mirjam M., Kowald, Axel, Gerisch, Birgit, Heeren, Gino, Struys, Eduard A., ...
Background Eukaryotic cells have evolved various response mechanisms to counteract the deleterious consequences of oxidative stress. Among these processes, metabolic alterations seem to play an...
Ralser, Markus, Heeren, Gino, Breitenbach, Michael, Lehrach, Hans, Krobitsch, Sylvia
Triosephosphate isomerase (TPI) deficiency is an autosomal recessive disorder caused by various mutations in the gene encoding the key glycolytic enzyme TPI. A drastic decrease in TPI activity and an...
An efficient and economic enhancer mix for PCR (2006)
Ralser, Markus, Querfurth, Robert, Warnatz, Hans-Jörg, Lehrach, Hans, Yaspo, Marie-Laure, Krobitsch, Sylvia
Polymerase chain reaction (PCR) has become a fundamental technique in molecular biology. Nonetheless, further improvements of the existing protocols are required to broaden the applicability of PCR...
An integrative approach to gain insights into the cellular function of human ataxin-2 (2005)
Ralser, Markus, Albrecht, Mario, Nonhoff, Ute, Lengauer, Thomas, Lehrach, Hans, Krobitsch, Sylvia
Spinocerebellar ataxia type 2 (SCA2) is a hereditary neurodegenerative disorder caused by a trinucleotide expansion in the SCA2 gene, encoding a polyglutamine stretch in the gene product ataxin-2...
Generation of a yeast two-hybrid strain suitable for competitive protein binding analysis (2005)
Ralser, Markus, Goehler, Heike, Wanker, Erich E., Lehrach, Hans, Krobitsch, Sylvia
Ralser, Markus, Nonhoff, Ute, Albrecht, Mario, Lengauer, Thomas, Wanker, Erich E., Lehrach, Hans, ...
Spinocerebellar ataxia type 2 is an inherited neurodegenerative disorder that is caused by an expanded trinucleotide repeat in the SCA2 gene, encoding a polyglutamine stretch in the gene product...
Ralser, Markus, Heeren, Gino, Breitenbach, Michael, Lehrach, Hans, Krobitsch, Sylvia
Triosephosphate isomerase (TPI) deficiency is an autosomal recessive disorder caused by various mutations in the gene encoding the key glycolytic enzyme TPI. A drastic decrease in TPI activity and an...
Nonhoff, Ute, Ralser, Markus, Welzel, Franziska, Piccini, Ilaria, Balzereit, Daniela, Yaspo, Marie-Laure, ...
Tight control of translation is fundamental for eukaryotic cells, and deregulation of proteins implicated contributes to numerous human diseases. The neurodegenerative disorder spinocerebellar ataxia...
Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress
Ralser, Markus, Wamelink, Mirjam M, Kowald, Axel, Gerisch, Birgit, Heeren, Gino, Struys, Eduard A, ...
Ralser, Markus, Nebel, Almut, Kleindorp, Rabea, Krobitsch, Sylvia, Lehrach, Hans, Schreiber, Stefan, ...
Reductive stress on life span extension in C. elegans
Ralser, Markus, Benjamin, Ivor J
Recently, Schulz and colleagues have contributed to the ongoing controversy on the unproven role of oxidative stress in the aging process in their well-performed study 'Glucose restriction extends...