Mark P. Boldin

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder (2008)

O'Connell, Ryan M., Rao, Dinesh S., Chaudhuri, Aadel A., Boldin, Mark P., Taganov, Konstnatin D., Nicoll, John, ...

Mammalian microRNAs are emerging as key regulators of the development and function of the immune system. Here, we report a strong but transient induction of miR-155 in mouse bone marrow after...

MicroRNA-155 is induced during the macrophage inflammatory response (2007)

O'Connell, Ryan M., Taganov, Konstantin D., Boldin, Mark P., Cheng, Genhong, Baltimore, David

The mammalian inflammatory response to infection involves the induction of several hundred genes, a process that must be carefully regulated to achieve pathogen clearance and prevent the consequences...

NF-{kappa}B-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses (2006)

Taganov, Konstantin D., Boldin, Mark P., Chang, Kuang-Jung, Baltimore, David

Activation of mammalian innate and acquired immune responses must be tightly regulated by elaborate mechanisms to control their onset and termination. MicroRNAs have been implicated as negative...

How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-κB activation by members of the TNF/NGF receptor family (2002)

Wallach, David, Arumugam, Thangavelu U, Boldin, Mark P, Cantarella, Giuseppina, Ganesh, Koluman A, Goltsev, Yuri, ...

Chapter summary Signals emanating from receptors of the tumor necrosis factor/nerve growth factor (TNF/NGF) family control practically all aspects of immune defense and, as such, constitute potential...

NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

Taganov, Konstantin D., Boldin, Mark P., Chang, Kuang-Jung, Baltimore, David

Activation of mammalian innate and acquired immune responses must be tightly regulated by elaborate mechanisms to control their onset and termination. MicroRNAs have been implicated as negative...

MicroRNA-155 is induced during the macrophage inflammatory response

O'Connell, Ryan M., Taganov, Konstantin D., Boldin, Mark P., Cheng, Genhong, Baltimore, David

The mammalian inflammatory response to infection involves the induction of several hundred genes, a process that must be carefully regulated to achieve pathogen clearance and prevent the consequences...

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

O'Connell, Ryan M., Rao, Dinesh S., Chaudhuri, Aadel A., Boldin, Mark P., Taganov, Konstantin D., Nicoll, John, ...

Mammalian microRNAs are emerging as key regulators of the development and function of the immune system. Here, we report a strong but transient induction of miR-155 in mouse bone marrow after...