Marion Bérard

Prolonged exposure of naïve CD8+ T cells to interleukin-7 or interleukin-15 stimulates proliferation without differentiation or loss of telomere length

Wallace, Diana L, Bérard, Marion, Soares, Maria V D, Oldham, Janine, Cook, Joanne E, Akbar, Arne N, ...

Interleukin (IL)-7 and IL-15 are cytokines implicated in homeostatic control of the peripheral CD8 T-cell pool. We compared the effects of IL-7 and IL-15 on survival and proliferation of purified...

Flice-Inhibitory Protein Is a Key Regulator of Germinal Center B Cell Apoptosis

Hennino, Ana, Bérard, Marion, Krammer, Peter H., Defrance, Thierry

Affinity maturation of the B cell response to antigen (Ag) takes place in the germinal centers (GCs) of secondary follicles. Two sequential molecular mechanisms underpin this process. First, the B...