Huang, Shixia, Li, Yi, Chen, Yidong, Podsypanina, Katrina, Chamorro, Mario, Olshen, Adam B, ...
Abstract Background In human breast cancer normal mammary cells typically develop into hyperplasia, ductal carcinoma in situ , invasive cancer, and metastasis. The changes in gene expression...
Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk (2001)
Chamorro, Mario, Czar, Michael J, Debnath, Jayanta, Cheng, Genhong, Lenardo, Michael J, Varmus, Harold E, ...
Abstract Background The Tec family kinases are implicated in signaling from lymphocyte antigen receptors and are activated following phosphorylation by Src kinases. For most Tec kinases, this...
Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk
Chamorro, Mario, Czar, Michael J, Debnath, Jayanta, Cheng, Genhong, Lenardo, Michael J, Varmus, Harold E, ...
rlk/TXK Encodes Two Forms of a Novel Cysteine String Tyrosine Kinase Activated by Src Family Kinases
Debnath, Jayantha, Chamorro, Mario, Czar, Michael J., Schaeffer, Edward M., Lenardo, Michael J., Varmus, Harold E., ...
Rlk/Txk is a member of the BTK/Tec family of tyrosine kinases and is primarily expressed in T lymphocytes. Unlike other members of this kinase family, Rlk lacks a pleckstrin homology (PH) domain near...
Requirement for a Nuclear Function of β-Catenin in Wnt Signaling
Cong, Feng, Schweizer, Liang, Chamorro, Mario, Varmus, Harold
Wnt signaling stabilizes β-catenin, which in turn influences the transcription of Wnt-responsive genes in conjunction with T-cell factor (TCF) transcription factors. At present, there are two models...
Li, Yi, Welm, Bryan, Podsypanina, Katrina, Huang, Shixia, Chamorro, Mario, Zhang, Xiaomei, ...
Breast cancer is a genetically and clinically heterogeneous disease, and the contributions of different target cells and different oncogenic mutations to this heterogeneity are not well understood....
Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice
Huang, Shixia, Li, Yi, Chen, Yidong, Podsypanina, Katrina, Chamorro, Mario, Olshen, Adam B, ...
cDNA microarray-derived expression profiles of MMTV-Wnt-1 and MMTV-Neu transgenic mice reveal several hundred genes to be differentially expressed at each stage of breast tumor development.
Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk
Chamorro, Mario, Czar, Michael J, Debnath, Jayanta, Cheng, Genhong, Lenardo, Michael J, Varmus, Harold E, ...
rlk/TXK Encodes Two Forms of a Novel Cysteine String Tyrosine Kinase Activated by Src Family Kinases
Debnath, Jayantha, Chamorro, Mario, Czar, Michael J., Schaeffer, Edward M., Lenardo, Michael J., Varmus, Harold E., ...
Rlk/Txk is a member of the BTK/Tec family of tyrosine kinases and is primarily expressed in T lymphocytes. Unlike other members of this kinase family, Rlk lacks a pleckstrin homology (PH) domain near...
Requirement for a Nuclear Function of β-Catenin in Wnt Signaling
Cong, Feng, Schweizer, Liang, Chamorro, Mario, Varmus, Harold
Wnt signaling stabilizes β-catenin, which in turn influences the transcription of Wnt-responsive genes in conjunction with T-cell factor (TCF) transcription factors. At present, there are two models...
Li, Yi, Welm, Bryan, Podsypanina, Katrina, Huang, Shixia, Chamorro, Mario, Zhang, Xiaomei, ...
Breast cancer is a genetically and clinically heterogeneous disease, and the contributions of different target cells and different oncogenic mutations to this heterogeneity are not well understood....
Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice
Huang, Shixia, Li, Yi, Chen, Yidong, Podsypanina, Katrina, Chamorro, Mario, Olshen, Adam B, ...
cDNA microarray-derived expression profiles of MMTV-Wnt-1 and MMTV-Neu transgenic mice reveal several hundred genes to be differentially expressed at each stage of breast tumor development.