Tangle analysis of difference topology experiments: applications to a Mu protein-DNA complex (2007)
Darcy, Isabel K., Luecke, John, Vazquez, Mariel
We develop topological methods for analyzing difference topology experiments involving 3-string tangles. Difference topology is a novel technique used to unveil the structure of stable protein-DNA...
DNA knots reveal a chiral organization of DNA in phage capsids
Arsuaga, Javier, Vazquez, Mariel, McGuirk, Paul, Trigueros, Sonia, Sumners, De Witt, Roca, Joaquim
Icosahedral bacteriophages pack their double-stranded DNA genomes to near-crystalline density and achieve one of the highest levels of DNA condensation found in nature. Despite numerous studies, some...
DNA knots reveal a chiral organization of DNA in phage capsids
Arsuaga, Javier, Vazquez, Mariel, McGuirk, Paul, Trigueros, Sonia, Sumners, De Witt, Roca, Joaquim
Icosahedral bacteriophages pack their double-stranded DNA genomes to near-crystalline density and achieve one of the highest levels of DNA condensation found in nature. Despite numerous studies, some...
Unlinking chromosome catenanes in vivo by site-specific recombination
Grainge, Ian, Bregu, Migena, Vazquez, Mariel, Sivanathan, Viknesh, Ip, Stephen C Y, Sherratt, David J
A challenge for chromosome segregation in all domains of life is the formation of catenated progeny chromosomes, which arise during replication as a consequence of the interwound strands of the DNA...