Tomasz, Maria, Barton, Jacqueline K., Magliozzo, Catherine C., Tucker, David, Lafer, Eileen M., Stollar, B. David
Poly(dG-dC)· poly(dG-dC) and Micrococcus lysodeikticus DNA were modified by exposure to reductively activated mitomycin C, an antitumor antibiotic. The resulting covalent drug-polynucleotide...
Absence of Strand Breaks in Deoxyribonucleic Acid Treated with Metronidazole
LaRusso, Nicholas F., Tomasz, Maria, Kaplan, David, Müller, Miklós
The deoxyribonucleic acid (DNA)-degrading potential of metronidazole was evaluated in vitro by three techniques: determination of melting curve, measurement of viscosity, and centrifugation in...
Inhibitory Effects of Mitomycin-Related Compounds Lacking the C1-C2 Aziridine Ring
Mercado, Carmen M., Tomasz, Maria
Three chemical derivatives of mitomycin C cause loss of viability, inhibition of deoxyribonucleic acid synthesis, and inhibition of cell division in bacteria. Each of these drugs lacks the C1-C2...
Absence of Strand Breaks in Deoxyribonucleic Acid Treated with Metronidazole
LaRusso, Nicholas F., Tomasz, Maria, Kaplan, David, Müller, Miklós
The deoxyribonucleic acid (DNA)-degrading potential of metronidazole was evaluated in vitro by three techniques: determination of melting curve, measurement of viscosity, and centrifugation in...
Inhibitory Effects of Mitomycin-Related Compounds Lacking the C1-C2 Aziridine Ring
Mercado, Carmen M., Tomasz, Maria
Three chemical derivatives of mitomycin C cause loss of viability, inhibition of deoxyribonucleic acid synthesis, and inhibition of cell division in bacteria. Each of these drugs lacks the C1-C2...