Maria Ciaramella

An Lrp-Like Protein of the Hyperthermophilic Archaeon Sulfolobus solfataricus Which Binds to Its Own Promoter†

Napoli, Alessandra, Van Der Oost, John, Sensen, Christoph W., Charlebois, Robert L., Rossi, Mosé, Ciaramella, Maria

Regulation of gene expression in the domain Archaea, and specifically hyperthermophiles, has been poorly investigated so far. Biochemical experiments and genome sequencing have shown that, despite...

DNA bending, compaction and negative supercoiling by the architectural protein Sso7d of Sulfolobus solfataricus

Napoli, Alessandra, Zivanovic, Yvan, Bocs, Chantal, Buhler, Cyril, Rossi, Mose’, Forterre, Patrick, ...

Members of the Sso7d/Sac7d family are small, abundant, non-specific DNA-binding proteins of the hyperthermophilic Archaea Sulfolobus. Crystal structures of these proteins in complex with...

Transcriptional response to DNA damage in the archaeon Sulfolobus solfataricus

Salerno, Vincenzo, Napoli, Alessandra, White, Malcolm F., Rossi, Mosè, Ciaramella, Maria

Exposure of cells to DNA-damaging agents triggers a complex biological response involving cell cycle arrest and modulation of gene expression. Genomic sequencing has revealed the presence of archaeal...

Functional interaction of reverse gyrase with single-strand binding protein of the archaeon Sulfolobus

Napoli, Alessandra, Valenti, Anna, Salerno, Vincenzo, Nadal, Marc, Garnier, Florence, Rossi, Mosè, ...

Reverse gyrase is a unique hyperthermophile-specific DNA topoisomerase that induces positive supercoiling. It is a modular enzyme composed of a topoisomerase IA and a helicase domain, which cooperate...

Selective degradation of reverse gyrase and DNA fragmentation induced by alkylating agent in the archaeon Sulfolobus solfataricus

Valenti, Anna, Napoli, Alessandra, Ferrara, Maria Carmina, Nadal, Marc, Rossi, Mosè, Ciaramella, Maria

Reverse gyrase is a peculiar DNA topoisomerase, specific of hyperthermophilic Archaea and Bacteria, which has the unique ability of introducing positive supercoiling into DNA molecules. Although the...

An Lrp-Like Protein of the Hyperthermophilic Archaeon Sulfolobus solfataricus Which Binds to Its Own Promoter†

Napoli, Alessandra, Van Der Oost, John, Sensen, Christoph W., Charlebois, Robert L., Rossi, Mosé, Ciaramella, Maria

Regulation of gene expression in the domain Archaea, and specifically hyperthermophiles, has been poorly investigated so far. Biochemical experiments and genome sequencing have shown that, despite...

DNA bending, compaction and negative supercoiling by the architectural protein Sso7d of Sulfolobus solfataricus

Napoli, Alessandra, Zivanovic, Yvan, Bocs, Chantal, Buhler, Cyril, Rossi, Mose’, Forterre, Patrick, ...

Members of the Sso7d/Sac7d family are small, abundant, non-specific DNA-binding proteins of the hyperthermophilic Archaea Sulfolobus. Crystal structures of these proteins in complex with...

Transcriptional response to DNA damage in the archaeon Sulfolobus solfataricus

Salerno, Vincenzo, Napoli, Alessandra, White, Malcolm F., Rossi, Mosè, Ciaramella, Maria

Exposure of cells to DNA-damaging agents triggers a complex biological response involving cell cycle arrest and modulation of gene expression. Genomic sequencing has revealed the presence of archaeal...

Functional interaction of reverse gyrase with single-strand binding protein of the archaeon Sulfolobus

Napoli, Alessandra, Valenti, Anna, Salerno, Vincenzo, Nadal, Marc, Garnier, Florence, Rossi, Mosè, ...

Reverse gyrase is a unique hyperthermophile-specific DNA topoisomerase that induces positive supercoiling. It is a modular enzyme composed of a topoisomerase IA and a helicase domain, which cooperate...

Selective degradation of reverse gyrase and DNA fragmentation induced by alkylating agent in the archaeon Sulfolobus solfataricus

Valenti, Anna, Napoli, Alessandra, Ferrara, Maria Carmina, Nadal, Marc, Rossi, Mosè, Ciaramella, Maria

Reverse gyrase is a peculiar DNA topoisomerase, specific of hyperthermophilic Archaea and Bacteria, which has the unique ability of introducing positive supercoiling into DNA molecules. Although the...

Dissection of reverse gyrase activities: insight into the evolution of a thermostable molecular machine†

Valenti, Anna, Perugino, Giuseppe, D’Amaro, Anna, Cacace, Andrea, Napoli, Alessandra, Rossi, Mosè, ...

Reverse gyrase is a peculiar DNA topoisomerase, specific of thermophilic microorganisms, which induces positive supercoiling into DNA molecules in an ATP-dependent reaction. It is a modular enzyme...