Maria Capovilla

Constitutive expression of a complement-like protein in Toll and JAK gain-of-function mutants of Drosophila

Lagueux, Marie, Perrodou, Emmanuel, Levashina, Elena A., Capovilla, Maria, Hoffmann, Jules A.

We show that Drosophila expresses four genes encoding proteins with significant similarities with the thiolester-containing proteins of the complement C3/α2-macroglobulin superfamily. The genes are...

DmMyD88 controls dorsoventral patterning of the Drosophila embryo

Kambris, Zakaria, Bilak, Hana, D'Alessandro, Rosalba, Belvin, Marcia, Imler, Jean-Luc, Capovilla, Maria

MyD88 is an adapter protein in the signal transduction pathway mediated by interleukin-1 (IL-1) and Toll-like receptors. A Drosophila homologue of MyD88 (DmMyD88) was recently shown to be required...

Constitutive expression of a complement-like protein in Toll and JAK gain-of-function mutants of Drosophila

Lagueux, Marie, Perrodou, Emmanuel, Levashina, Elena A., Capovilla, Maria, Hoffmann, Jules A.

We show that Drosophila expresses four genes encoding proteins with significant similarities with the thiolester-containing proteins of the complement C3/α2-macroglobulin superfamily. The genes are...

DmMyD88 controls dorsoventral patterning of the Drosophila embryo

Kambris, Zakaria, Bilak, Hana, D'Alessandro, Rosalba, Belvin, Marcia, Imler, Jean-Luc, Capovilla, Maria

MyD88 is an adapter protein in the signal transduction pathway mediated by interleukin-1 (IL-1) and Toll-like receptors. A Drosophila homologue of MyD88 (DmMyD88) was recently shown to be required...