Marcus Furch

Structural Features of Cross-Bridges in Isometrically Contracting Skeletal Muscle (2002)

Kraft,Theresia, Mattei,Thomas, Radocaj,Ante, Piep,Birgit, Nocula,Christoph, Furch,Marcus, ...

Two-dimensional x-ray diffraction was used to investigate structural features of cross-bridges that generate force in isometrically contracting skeletal muscle. Diffraction patterns were recorded...

Structural Features of Cross-Bridges in Isometrically Contracting Skeletal Muscle (2002)

Kraft, Theresia, Mattei, Thomas, Radocaj, Ante, Piep, Birgit, Nocula, Christoph, Furch, Marcus, ...

Two-dimensional x-ray diffraction was used to investigate structural features of cross-bridges that generate force in isometrically contracting skeletal muscle. Diffraction patterns were recorded...

Single-molecule tracking of myosins with genetically engineered amplifier domains (2001)

Ruff,Christine, Furch,Marcus, Brenner,Bernhard, Manstein,Dietmar J., Meyhöfer,Edgar

We combined protein engineering and single molecule measurements to directly record the step size of a series of myosin constructs with shortened and elongated artificial neck domains. Our results...

Single-molecule tracking of myosins with genetically engineered amplifier domains (2001)

Ruff, Christine, Furch, Marcus, Brenner, Bernhard, Manstein, Dietmar J., Meyhöfer, Edgar

We combined protein engineering and single molecule measurements to directly record the step size of a series of myosin constructs with shortened and elongated artificial neck domains. Our results...

Stabilization of the actomyosin complex by negative charges on myosin (2000)

Furch,Marcus, Remmel,Bettina, Geeves,Michael A., Manstein,Dietmar J.

Sequence comparisons of members of the myosin superfamily show a high degree of charge conservation in a surface exposed helix (Dictyostelium discoideum myosin II heavy chain residues S510 to K546)....

Charge changes in loop 2 affect the thermal unfolding of the myosin motor domain bound to F-actin (2000)

Ponomarev,Michael A., Furch,Marcus, Levitsky,Dmitrii I., Manstein,Dietmar J.

The thermal unfolding of Dictyostelium discoideum myosin head fragments with alterations in the actin-binding surface loop 2 was studied by differential scanning calorimetry. Lengthening of loop 2...

Stabilization of the actomyosin complex by negative charges on myosin (2000)

Furch, Marcus, Remmel, Bettina, Geeves, Michael A., Manstein, Dietmar J.

Sequence comparisons of members of the myosin superfamily show a high degree of charge conservation in a surface exposed helix (Dictyostelium discoideum myosin II heavy chain residues S510 to K546)....

Charge changes in loop 2 affect the thermal unfolding of the myosin motor domain bound to F-actin (2000)

Ponomarev, Michael A., Furch, Marcus, Levitsky, Dmitrii I., Manstein, Dietmar J.

The thermal unfolding of Dictyostelium discoideum myosin head fragments with alterations in the actin-binding surface loop 2 was studied by differential scanning calorimetry. Lengthening of loop 2...

Role of the salt-bridge between switch-1 and switch-2 of Dictyostelium myosin (1999)

Furch,Marcus, Fujita-Becker,Setsuko, Geeves,Michael A., Holmes,Kenneth C., Manstein,Dietmar J.

Motifs N2 and N3, also referred to as switch-1 and switch-2, form part of the active site of molecular motors such as myosins and kinesins. In the case of myosin, N3 is thought to act as a...

Role of the salt-bridge between switch-1 and switch-2 of Dictyostelium myosin (1999)

Furch, Marcus, Fujita-Becker, Setsuko, Geeves, Michael A., Holmes, Kenneth C., Manstein, Dietmar J.

Motifs N2 and N3, also referred to as switch-1 and switch-2, form part of the active site of molecular motors such as myosins and kinesins. In the case of myosin, N3 is thought to act as a...

Modulation of actin affinity and actomyosin adenosine triphosphatase by charge changes in the myosin motor domain (1998)

Furch,Marcus, Geeves,Michael A., Manstein,Dietmar J.

The effects of mutations in an actin-binding surface loop of myosin (loop 2) are described. Part of loop 2, the segment between myosin residues 618 and 622, was replaced with sequences enlarged by...

Modulation of actin affinity and actomyosin adenosine triphosphatase by charge changes in the myosin motor domain (1998)

Furch, Marcus, Geeves, Michael A., Manstein, Dietmar J.

The effects of mutations in an actin-binding surface loop of myosin (loop 2) are described. Part of loop 2, the segment between myosin residues 618 and 622, was replaced with sequences enlarged by...