María-Paz García-Cuéllar

The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation

Birke, Marco, Schreiner, Silke, García-Cuéllar, María-Paz, Mahr, Kerstin, Titgemeyer, Fritz, Slany, Robert K.

Alterations of the proto-oncogene MLL (mixed lineage leukemia) are characteristic for a high proportion of acute leukemias, especially those occurring in infants. The activation of MLL is achieved...

Hoxa9 and Meis1 Are Key Targets for MLL-ENL-Mediated Cellular Immortalization

Zeisig, Bernd B., Milne, Tom, García-Cuéllar, María-Paz, Schreiner, Silke, Martin, Mary-Ellen, Fuchs, Uta, ...

MLL fusion proteins are oncogenic transcription factors that are associated with aggressive lymphoid and myeloid leukemias. We constructed an inducible MLL fusion, MLL-ENL-ERtm, that rendered the...

The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation

Birke, Marco, Schreiner, Silke, García-Cuéllar, María-Paz, Mahr, Kerstin, Titgemeyer, Fritz, Slany, Robert K.

Alterations of the proto-oncogene MLL (mixed lineage leukemia) are characteristic for a high proportion of acute leukemias, especially those occurring in infants. The activation of MLL is achieved...

Hoxa9 and Meis1 Are Key Targets for MLL-ENL-Mediated Cellular Immortalization

Zeisig, Bernd B., Milne, Tom, García-Cuéllar, María-Paz, Schreiner, Silke, Martin, Mary-Ellen, Fuchs, Uta, ...

MLL fusion proteins are oncogenic transcription factors that are associated with aggressive lymphoid and myeloid leukemias. We constructed an inducible MLL fusion, MLL-ENL-ERtm, that rendered the...