Makoto Furutani-Seiki

The DNA sequence of medaka chromosome LG22 (2007)

Sasaki, Takashi, Shimizu, Atsushi, Ishikawa, Sabine K., Imai, Shuichiro, Asakawa, Shuichi, Murayama, Yuji, ...

We report the genomic DNA sequence of a single chromosome (linkage group 22; LG22) of the small teleost fish medaka (Oryzias latipes) as a first whole chromosome sequence from a non-mammalian...

Generation of medaka gene knockout models by target-selected mutagenesis (2006)

Taniguchi, Yoshihito, Takeda, Shunichi, Furutani-Seiki, Makoto, Kamei, Yasuhiro, Todo, Takeshi, Sasado, Takao, ...

Abstract We have established a reverse genetics approach for the routine generation of medaka ( Oryzias latipes ) gene knockouts. A cryopreserved library of N -ethyl- N -nitrosourea (ENU) mutagenized...

MEPD: a Medaka gene expression pattern database

Henrich, Thorsten, Ramialison, Mirana, Quiring, Rebecca, Wittbrodt, Beate, Furutani-Seiki, Makoto, Wittbrodt, Joachim, ...

The Medaka Expression Pattern Database (MEPD) stores and integrates information of gene expression during embryonic development of the small freshwater fish Medaka (Oryzias latipes). Expression...

MEPD: a Medaka gene expression pattern database

Henrich, Thorsten, Ramialison, Mirana, Quiring, Rebecca, Wittbrodt, Beate, Furutani-Seiki, Makoto, Wittbrodt, Joachim, ...

The Medaka Expression Pattern Database (MEPD) stores and integrates information of gene expression during embryonic development of the small freshwater fish Medaka (Oryzias latipes). Expression...

Generation of medaka gene knockout models by target-selected mutagenesis

Taniguchi, Yoshihito, Takeda, Shunichi, Furutani-Seiki, Makoto, Kamei, Yasuhiro, Todo, Takeshi, Sasado, Takao, ...

A reverse genetics approach for the routine generation of medaka (Oryzias latipes) gene knockouts is described and applied to create a cryopreserved resource containing knockouts for most medaka...

The hotei mutation of medaka in the anti-Müllerian hormone receptor causes the dysregulation of germ cell and sexual development

Morinaga, Chikako, Saito, Daisuke, Nakamura, Shuhei, Sasaki, Takashi, Asakawa, Shuichi, Shimizu, Nobuyoshi, ...

We previously performed mutant screens in the medaka for defects in gonadal development and identified a mutant of interest in this regard, which was designated as hotei (hot). This mutant manifests...

Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/β-catenin activity

Westfall, Trudi A., Brimeyer, Ryan, Twedt, Jen, Gladon, Jean, Olberding, Andrea, Furutani-Seiki, Makoto, ...

We provide genetic evidence defining a role for noncanonical Wnt function in vertebrate axis formation. In zebrafish, misexpression of Wnt-4, -5, and -11 stimulates calcium (Ca2+) release, defining...

WDR55 Is a Nucleolar Modulator of Ribosomal RNA Synthesis, Cell Cycle Progression, and Teleost Organ Development

Iwanami, Norimasa, Higuchi, Tomokazu, Sasano, Yumi, Fujiwara, Toshinobu, Hoa, Vu Q., Okada, Minoru, ...

The thymus is a vertebrate-specific organ where T lymphocytes are generated. Genetic programs that lead to thymus development are incompletely understood. We previously screened...