Carlson, Bradley A., Moustafa, Mohamed E., Sengupta, Aniruddha, Schweizer, Ulrich, Shrimali, Rajeev, Rao, Mahadev, ...
Novel mouse models were developed in which the hepatic selenoprotein population was targeted for removal by disrupting the selenocysteine (Sec) tRNA [Ser]Sec gene (trsp) and then selenoprotein...
Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth (2007)
Wu, Kongming, Liu, Manran, Li, Anping, Donninger, Howard, Rao, Mahadev, Jiao, Xuanmao, ...
The cell fate determination factor DACH1 plays a key role in cellular differentiation in metazoans. DACH1 is engaged in multiple context-dependent complexes that activate or repress transcription....
Identification and characterization of phosphoseryl-tRNA [Ser]Sec kinase (2004)
Carlson, Bradley A., Xu, Xue-Ming, Kryukov, Gregory V., Rao, Mahadev, Berry, Marla J., Gladyshev, Vadim N., ...
In 1970, a kinase activity that phosphorylated a minor species of seryl-tRNA to form phosphoseryl-tRNA was found in rooster liver [Maenpaa, P. H. & Bernfield, M. R. (1970) Proc. Natl. Acad. Sci. USA...
Chlamydomonas reinhardtii selenocysteine tRNA [Ser]Sec (2003)
Rao, Mahadev, Carlson, Bradley A., Novoselov, Sergey V., Weeks, Donald P., Gladyshev, Vadim, Hatfield, Dolph L.
Eukaryotic selenocysteine (Sec) protein insertion machinery was thought to be restricted to animals, but the occurrence of both Sec-containing proteins and the Sec insertion system was recently found...
Novoselov, Sergey V., Rao, Mahadev, Onoshko, Natalia V., Zhi, Huijun, Kryukov, Gregory V., Xiang, Youbin, ...
Known eukaryotic selenocysteine (Sec)-containing proteins are animal proteins, whereas selenoproteins have not been found in yeast and plants. Surprisingly, we detected selenoproteins in a member of...
Novoselov, Sergey V., Rao, Mahadev, Onoshko, Natalia V., Zhi, Huijun, Kryukov, Gregory V., Xiang, Youbin, ...
Known eukaryotic selenocysteine (Sec)-containing proteins are animal proteins, whereas selenoproteins have not been found in yeast and plants. Surprisingly, we detected selenoproteins in a member of...
Fu, Maofu, Rao, Mahadev, Wang, Chenguang, Sakamaki, Toshiyuki, Wang, Jian, Di Vizio, Dolores, ...
Modification by acetylation occurs at ɛ-amino lysine residues of histones and transcription factors. Unlike phosphorylation, a direct link between transcription factor acetylation and cellular...
Hulit, James, Wang, Chenguang, Li, Zhiping, Albanese, Chris, Rao, Mahadev, Di Vizio, Dolores, ...
Constitutive β-catenin/Tcf activity, the primary transforming events in colorectal carcinoma, occurs through induction of the Wnt pathway or APC gene mutations that cause familial adenomatous...
Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase
Carlson, Bradley A., Xu, Xue-Ming, Kryukov, Gregory V., Rao, Mahadev, Berry, Marla J., Gladyshev, Vadim N., ...
In 1970, a kinase activity that phosphorylated a minor species of seryl-tRNA to form phosphoseryl-tRNA was found in rooster liver [Maenpaa, P. H. & Bernfield, M. R. (1970) Proc. Natl. Acad. Sci. USA...
Chlamydomonas reinhardtii selenocysteine tRNA[Ser]Sec
RAO, MAHADEV, CARLSON, BRADLEY A., NOVOSELOV, SERGEY V., WEEKS, DONALD P., GLADYSHEV, VADIM N., HATFIELD, DOLPH L.
Eukaryotic selenocysteine (Sec) protein insertion machinery was thought to be restricted to animals, but the occurrence of both Sec-containing proteins and the Sec insertion system was recently found...
Novoselov, Sergey V., Rao, Mahadev, Onoshko, Natalia V., Zhi, Huijun, Kryukov, Gregory V., Xiang, Youbin, ...
Known eukaryotic selenocysteine (Sec)-containing proteins are animal proteins, whereas selenoproteins have not been found in yeast and plants. Surprisingly, we detected selenoproteins in a member of...
Fu, Maofu, Rao, Mahadev, Wang, Chenguang, Sakamaki, Toshiyuki, Wang, Jian, Di Vizio, Dolores, ...
Modification by acetylation occurs at ɛ-amino lysine residues of histones and transcription factors. Unlike phosphorylation, a direct link between transcription factor acetylation and cellular...
Hulit, James, Wang, Chenguang, Li, Zhiping, Albanese, Chris, Rao, Mahadev, Di Vizio, Dolores, ...
Constitutive β-catenin/Tcf activity, the primary transforming events in colorectal carcinoma, occurs through induction of the Wnt pathway or APC gene mutations that cause familial adenomatous...
Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase
Carlson, Bradley A., Xu, Xue-Ming, Kryukov, Gregory V., Rao, Mahadev, Berry, Marla J., Gladyshev, Vadim N., ...
In 1970, a kinase activity that phosphorylated a minor species of seryl-tRNA to form phosphoseryl-tRNA was found in rooster liver [Maenpaa, P. H. & Bernfield, M. R. (1970) Proc. Natl. Acad. Sci. USA...
Chlamydomonas reinhardtii selenocysteine tRNA[Ser]Sec
RAO, MAHADEV, CARLSON, BRADLEY A., NOVOSELOV, SERGEY V., WEEKS, DONALD P., GLADYSHEV, VADIM N., HATFIELD, DOLPH L.
Eukaryotic selenocysteine (Sec) protein insertion machinery was thought to be restricted to animals, but the occurrence of both Sec-containing proteins and the Sec insertion system was recently found...
DACH1 Is a Cell Fate Determination Factor That Inhibits Cyclin D1 and Breast Tumor Growth†
Wu, Kongming, Li, Anping, Rao, Mahadev, Liu, Manran, Dailey, Vernon, Yang, Ying, ...
Obstacles to the expansion of cells with proliferative potential include the induction of cell death, telomere-based senescence, and the pRb and p53 tumor suppressors. Not infrequently, the molecular...
Cell Fate Determination Factor DACH1 Inhibits c-Jun–induced Contact-independent Growth
Wu, Kongming, Liu, Manran, Li, Anping, Donninger, Howard, Rao, Mahadev, Jiao, Xuanmao, ...
The cell fate determination factor DACH1 plays a key role in cellular differentiation in metazoans. DACH1 is engaged in multiple context-dependent complexes that activate or repress transcription....
The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration
Di Giovanni, Simone, Knights, Chad D, Rao, Mahadev, Yakovlev, Alexander, Beers, Jeannette, Catania, Jason, ...
Axon regeneration is substantially regulated by gene expression and cytoskeleton remodeling. Here we show that the tumor suppressor protein p53 is required for neurite outgrowth in cultured cells...