Functional and physical interaction between Bcl-XL and a BH3-like domain in Beclin-1
Maiuri, M Chiara, Le Toumelin, Gaëtane, Criollo, Alfredo, Rain, Jean-Christophe, Gautier, Fabien, Juin, Philippe, ...
The anti-apoptotic proteins Bcl-2 and Bcl-XL bind and inhibit Beclin-1, an essential mediator of autophagy. Here, we demonstrate that this interaction involves a BH3 domain within Beclin-1 (residues...