Artem L. Ponomarev, Mauro Belli, Philip J. Hahnfeldt, Lynn Hlatky, Rainer K. Sachs, Francis A. Cucinotta
Modeling Intercellular Interactions during Carcinogenesis (2005)
Rainer K. Sachs, Michael Chan, Lynn Hlatky, Philip Hahnfeldt
Sachs, R. K., Chan, M., Hlatky, L. and Hahnfeldt, P. Modeling Intercellular Interactions during Carcinogenesis. Radiat. Res. 164, 324–331 (2005). By modulating the microenvironment of malignant or...
Using Graph Theory to Describe and Model Chromosome Aberrations (2002)
Rainer K. Sachs, Javier Arsuaga, Mariel Vázquez, Lynn Hlatky, Philip Hahnfeldt
Sachs, R. K., Arsuaga, J., Vázquez, M., Hlatky, L. and Hahnfeldt, P. Using Graph Theory to Describe and Model Chromosome Aberrations. Radiat. Res. 158, 556–567 (2002). A comprehensive description...
PPARγ ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis
Panigrahy, Dipak, Singer, Samuel, Shen, Lucy Q., Butterfield, Catherine E., Freedman, Deborah A., Chen, Emy J., ...
Several drugs approved for a variety of indications have been shown to exhibit antiangiogenic effects. Our study focuses on the PPARγ ligand rosiglitazone, a compound widely used in the treatment of...
PPARγ ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis
Panigrahy, Dipak, Singer, Samuel, Shen, Lucy Q., Butterfield, Catherine E., Freedman, Deborah A., Chen, Emy J., ...
Several drugs approved for a variety of indications have been shown to exhibit antiangiogenic effects. Our study focuses on the PPARγ ligand rosiglitazone, a compound widely used in the treatment of...
Transcriptional network governing the angiogenic switch in human pancreatic cancer
Abdollahi, Amir, Schwager, Christian, Kleeff, Jörg, Esposito, Irene, Domhan, Sophie, Peschke, Peter, ...
A shift of the angiogenic balance to the proangiogenic state, termed the “angiogenic switch,” is a hallmark of cancer progression. Here we devise a strategy for identifying genetic participants...
Chromosomes are predominantly located randomly with respect to each other in interphase human cells
Cornforth, Michael N., Greulich-Bode, Karin M., Loucas, Bradford D., Arsuaga, Javier, Vázquez, Mariel, Sachs, Rainer K., ...
To test quantitatively whether there are systematic chromosome–chromosome associations within human interphase nuclei, interchanges between all possible heterologous pairs of chromosomes were...