Liying Guo

In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production

Guo, Liying, Hu-Li, Jane, Zhu, Jinfang, Watson, Cynthia J., Difilippantonio, Michael J., Pannetier, Christophe, ...

TH2 clones may produce very variable amounts of IL-4. Among six TH2 clones prepared from homozygous or heterozygous mice in which Gfp replaced the first exon of Il4, a range of patterns of CpG...

Interleukin 2 plays a central role in Th2 differentiation

Cote-Sierra, Javier, Foucras, Gilles, Guo, Liying, Chiodetti, Lynda, Young, Howard A., Hu-Li, Jane, ...

Differentiation of naïve CD4 T cells into T helper (Th) 2 cells requires signaling through the T cell receptor and an appropriate cytokine environment. IL-4 is critical for such Th2 differentiation....

In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production

Guo, Liying, Hu-Li, Jane, Zhu, Jinfang, Watson, Cynthia J., Difilippantonio, Michael J., Pannetier, Christophe, ...

TH2 clones may produce very variable amounts of IL-4. Among six TH2 clones prepared from homozygous or heterozygous mice in which Gfp replaced the first exon of Il4, a range of patterns of CpG...

Interleukin 2 plays a central role in Th2 differentiation

Cote-Sierra, Javier, Foucras, Gilles, Guo, Liying, Chiodetti, Lynda, Young, Howard A., Hu-Li, Jane, ...

Differentiation of naïve CD4 T cells into T helper (Th) 2 cells requires signaling through the T cell receptor and an appropriate cytokine environment. IL-4 is critical for such Th2 differentiation....

Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion

Zhu, Jinfang, Jankovic, Dragana, Grinberg, Alex, Guo, Liying, Paul, William E.

Enforced expression of growth factor independent 1 (Gfi-1), a transcription repressor induced by T cell activation and IL-4/Stat6 signaling, strikingly enhances Th2 cell expansion. Using...

Transient Inhibition of Interleukin 4 Signaling by T Cell Receptor Ligation

Zhu, Jinfang, Huang, Hua, Guo, Liying, Stonehouse, Timothy, Watson, Cynthia J., Hu-Li, Jane, ...

Interleukin (IL)-4 and IL-12 together with T cell receptor (TCR) engagement are crucial for the differentiation of CD4+ T cells into T helper (Th)2 or Th1 cells, respectively. Although IL-4 receptors...

Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP

Takizawa, Takumi, Gudla, Prabhakar R., Guo, Liying, Lockett, Stephan, Misteli, Tom

Chromosomes and genes are nonrandomly arranged within the mammalian cell nucleus. However, the functional significance of nuclear positioning in gene expression is unclear. Here we directly probed...