Topological challenges to DNA replication: Conformations at the fork
Postow, Lisa, Crisona, Nancy J., Peter, Brian J., Hardy, Christine D., Cozzarelli, Nicholas R.
The unwinding of the parental DNA duplex during replication causes a positive linking number difference, or superhelical strain, to build up around the elongating replication fork. The branching at...
Topological domain structure of the Escherichia coli chromosome
Postow, Lisa, Hardy, Christine D., Arsuaga, Javier, Cozzarelli, Nicholas R.
The circular chromosome of Escherichia coli is organized into independently supercoiled loops, or topological domains. We investigated the organization and size of these domains in vivo and in vitro....
Topological challenges to DNA replication: Conformations at the fork
Postow, Lisa, Crisona, Nancy J., Peter, Brian J., Hardy, Christine D., Cozzarelli, Nicholas R.
The unwinding of the parental DNA duplex during replication causes a positive linking number difference, or superhelical strain, to build up around the elongating replication fork. The branching at...
Topological domain structure of the Escherichia coli chromosome
Postow, Lisa, Hardy, Christine D., Arsuaga, Javier, Cozzarelli, Nicholas R.
The circular chromosome of Escherichia coli is organized into independently supercoiled loops, or topological domains. We investigated the organization and size of these domains in vivo and in vitro....