Functional diversity of the RNA-binding proteins from the nucleus to the cytoplasm (2001)
Pre-mRNA/mRNA-binding proteins play critical and multifunctional roles in the post-transcriptional regulation of gene expression, including pre-mRNA processing, mRNA stability, transport and...
Wan, Lili, Dockendorff, Thomas C., Jongens, Thomas A., Dreyfuss, Gideon
Fragile X syndrome is the most common inherited form of mental retardation. It is caused by loss of FMR1 gene activity due to either lack of expression or expression of a mutant form of the protein....
Functional Conservation of the Transportin Nuclear Import Pathway in Divergent Organisms
Siomi, Mikiko C., Fromont, Micheline, Rain, Jean-Christophe, Wan, Lili, Wang, Fan, Legrain, Pierre, ...
Human transportin1 (hTRN1) is the nuclear import receptor for a group of pre-mRNA/mRNA-binding proteins (heterogeneous nuclear ribonucleoproteins [hnRNP]) represented by hnRNP A1, which shuttle...
Lymphotropic Herpesvirus saimiri Uses the SMN Complex To Assemble Sm Cores on Its Small RNAs
Golembe, Tracey J., Yong, Jeongsik, Battle, Daniel J., Feng, Wenqin, Wan, Lili, Dreyfuss, Gideon
The lymphotropic Herpesvirus saimiri (HVS) causes acute leukemia, T-cell lymphoma, and death in New World monkeys. HVS encodes seven small RNAs (HSURs) of unknown function. The HSURs acquire host Sm...
Wan, Lili, Battle, Daniel J., Yong, Jeongsik, Gubitz, Amelie K., Kolb, Stephen J., Wang, Jin, ...
Reduction of the survival of motor neurons (SMN) protein levels causes the motor neuron degenerative disease spinal muscular atrophy, the severity of which correlates with the extent of reduction in...
Wan, Lili, Dockendorff, Thomas C., Jongens, Thomas A., Dreyfuss, Gideon
Fragile X syndrome is the most common inherited form of mental retardation. It is caused by loss of FMR1 gene activity due to either lack of expression or expression of a mutant form of the protein....
Functional Conservation of the Transportin Nuclear Import Pathway in Divergent Organisms
Siomi, Mikiko C., Fromont, Micheline, Rain, Jean-Christophe, Wan, Lili, Wang, Fan, Legrain, Pierre, ...
Human transportin1 (hTRN1) is the nuclear import receptor for a group of pre-mRNA/mRNA-binding proteins (heterogeneous nuclear ribonucleoproteins [hnRNP]) represented by hnRNP A1, which shuttle...
Lymphotropic Herpesvirus saimiri Uses the SMN Complex To Assemble Sm Cores on Its Small RNAs
Golembe, Tracey J., Yong, Jeongsik, Battle, Daniel J., Feng, Wenqin, Wan, Lili, Dreyfuss, Gideon
The lymphotropic Herpesvirus saimiri (HVS) causes acute leukemia, T-cell lymphoma, and death in New World monkeys. HVS encodes seven small RNAs (HSURs) of unknown function. The HSURs acquire host Sm...
Wan, Lili, Battle, Daniel J., Yong, Jeongsik, Gubitz, Amelie K., Kolb, Stephen J., Wang, Jin, ...
Reduction of the survival of motor neurons (SMN) protein levels causes the motor neuron degenerative disease spinal muscular atrophy, the severity of which correlates with the extent of reduction in...
Transportin-mediated Nuclear Import of Heterogeneous Nuclear RNP Proteins
Siomi, Mikiko C., Eder, Paul S., Kataoka, Naoyuki, Wan, Lili, Liu, Qing, Dreyfuss, Gideon
Heterogeneous nuclear ribonucleoprotein (hnRNP) A1 is an abundant nuclear protein that plays an important role in pre-mRNA processing and mRNA export from the nucleus. A1 shuttles rapidly between the...