Lifeng Chen

Biochemical Characterization of the Tetrachlorobenzoquinone Reductase Involved in the Biodegradation of Pentachlorophenol (2008)

Lifeng Chen, Jian Yang

Pentachlorophenol (PCP), a xenobiocide used to preserve lumbers, is a major environmental pollutant in North America. In spite of an expected high resistance to biodegradation, a number of aquatic...

Identifying metabolic enzymes with multiple types of association evidence (2006)

Kharchenko, Peter, Chen, Lifeng, Freund, Yoav, Vitkup, Dennis, Church, George M

Abstract Background Existing large-scale metabolic models of sequenced organisms commonly include enzymatic functions which can not be attributed to any gene in that organism. Existing computational...

Predicting genes for orphan metabolic activities using phylogenetic profiles (2006)

Chen, Lifeng, Vitkup, Dennis

Abstract Homology-based methods fail to assign genes to many metabolic activities present in sequenced organisms. To suggest genes for these orphan activities we developed a novel method that...

Ethnic Identity and Mental Health of Young Chinese Immigrants (2000)

Chen, Lifeng

AIMS AND HYPOTHESIS: In Australia, there has been little research into the quality of young immigrants' mental health in relation to their ethnic identity and acculturation. This study aimed to...

Ethnic Identity and Mental Health of Young Chinese Immigrants (2000)

Chen, Lifeng

AIMS AND HYPOTHESIS: In Australia, there has been little research into the quality of young immigrants' mental health in relation to their ethnic identity and acculturation. This study aimed to...

Ethnic Identity and Mental Health of Young Chinese Immigrants (2000)

Chen, Lifeng

AIMS AND HYPOTHESIS: In Australia, there has been little research into the quality of young immigrants' mental health in relation to their ethnic identity and acculturation. This study aimed to...

Ethnic Identity and Mental Health of Young Chinese Immigrants (2000)

Chen, Lifeng

AIMS AND HYPOTHESIS: In Australia, there has been little research into the quality of young immigrants' mental health in relation to their ethnic identity and acculturation. This study aimed to...

Ethnic Identity and Mental Health of Young Chinese Immigrants (2000)

Chen, Lifeng

AIMS AND HYPOTHESIS: In Australia, there has been little research into the quality of young immigrants' mental health in relation to their ethnic identity and acculturation. This study aimed to...

Ethnic Identity and Mental Health of Young Chinese Immigrants (2000)

Chen, Lifeng

AIMS AND HYPOTHESIS: In Australia, there has been little research into the quality of young immigrants' mental health in relation to their ethnic identity and acculturation. This study aimed to...

Ethnic Identity and Mental Health of Young Chinese Immigrants (2000)

Chen, Lifeng

AIMS AND HYPOTHESIS: In Australia, there has been little research into the quality of young immigrants' mental health in relation to their ethnic identity and acculturation. This study aimed to...

Altered Regulation of 15-Acetyldeoxynivalenol Production in Fusarium graminearum

Chen, Lifeng, McCormick, Susan P., Hohn, Thomas M.

Most Fusarium graminearum isolates produce low or undetectable levels of trichothecenes in liquid shake cultures, making it difficult to perform biochemical studies of trichothecene biosynthesis. To...

Translational Accuracy during Exponential, Postdiauxic, and Stationary Growth Phases in Saccharomyces cerevisiae

Stahl, Guillaume, Salem, Samia N. Ben, Chen, Lifeng, Zhao, Bing, Farabaugh, Philip J.

When the yeast Saccharomyces cerevisiae shifts from rapid growth on glucose to slow growth on ethanol, it undergoes profound changes in cellular metabolism, including the destruction of most of the...

Predicting genes for orphan metabolic activities using phylogenetic profiles

Chen, Lifeng, Vitkup, Dennis

A method that combines local structure of a metabolic network with phylogenetic profiles is described and used to assign genes to orphan metabolic activities in yeast and Escherichia coli.

Altered Regulation of 15-Acetyldeoxynivalenol Production in Fusarium graminearum

Chen, Lifeng, McCormick, Susan P., Hohn, Thomas M.

Most Fusarium graminearum isolates produce low or undetectable levels of trichothecenes in liquid shake cultures, making it difficult to perform biochemical studies of trichothecene biosynthesis. To...

Translational Accuracy during Exponential, Postdiauxic, and Stationary Growth Phases in Saccharomyces cerevisiae

Stahl, Guillaume, Salem, Samia N. Ben, Chen, Lifeng, Zhao, Bing, Farabaugh, Philip J.

When the yeast Saccharomyces cerevisiae shifts from rapid growth on glucose to slow growth on ethanol, it undergoes profound changes in cellular metabolism, including the destruction of most of the...

Predicting genes for orphan metabolic activities using phylogenetic profiles

Chen, Lifeng, Vitkup, Dennis

A method that combines local structure of a metabolic network with phylogenetic profiles is described and used to assign genes to orphan metabolic activities in yeast and Escherichia coli.

Computational Prediction and Experimental Verification of the Gene Encoding the NAD+/NADP+-Dependent Succinate Semialdehyde Dehydrogenase in Escherichia coli▿ †

Fuhrer, Tobias, Chen, Lifeng, Sauer, Uwe, Vitkup, Dennis

Although NAD+-dependent succinate semialdehyde dehydrogenase activity was first described in Escherichia coli more than 25 years ago, the responsible gene has remained elusive so far. As an...