Signor, Dawn, Wedaman, Karen P., Rose, Lesilee S., Scholey, Jonathan M.
Chemosensation in the nervous system of the nematode Caenorhabditis elegans depends on sensory cilia, whose assembly and maintenance requires the transport of components such as axonemal proteins and...
Signor, Dawn, Wedaman, Karen P., Rose, Lesilee S., Scholey, Jonathan M.
Chemosensation in the nervous system of the nematode Caenorhabditis elegans depends on sensory cilia, whose assembly and maintenance requires the transport of components such as axonemal proteins and...
DeBella, Leah R., Hayashi, Adam, Rose, Lesilee S.
Spindle positioning is essential for the segregation of cell fate determinants during asymmetric division, as well as for proper cellular arrangements during development. In Caenorhabditis elegans...
Wu, Jui-Ching, Rose, Lesilee S.
The conserved PAR proteins are localized in asymmetric cortical domains and are required for the polarized localization of cell fate determinants in many organisms. In Caenorhabditis elegans embryos,...
Signor, Dawn, Wedaman, Karen P., Orozco, Jose T., Dwyer, Noelle D., Bargmann, Cornelia I., Rose, Lesilee S., ...
The heterotrimeric motor protein, kinesin-II, and its presumptive cargo, can be observed moving anterogradely at 0.7 μm/s by intraflagellar transport (IFT) within sensory cilia of chemosensory...
PAR-dependent and geometry-dependent mechanisms of spindle positioning
Tsou, Meng-Fu Bryan, Ku, Wei, Hayashi, Adam, Rose, Lesilee S.
During intrinsically asymmetric division, the spindle is oriented onto a polarized axis specified by a group of conserved PAR proteins. Extrinsic geometric asymmetry generated by cell shape also...
Zhu, Li, Wrabl, James O., Hayashi, Adam P., Rose, Lesilee S., Thomas, Philip J.
A subgroup of the AAA+ proteins that reside in the endoplasmic reticulum and the nuclear envelope including human torsinA, a protein mutated in hereditary dystonia, is called the torsin family of...