Genetic Variations of gpx-4 and Male Infertility in Humans1 (2003)
Matilde Maiorino, Valentina Bosello, Fulvio Ursini, Carlo Foresta, Andrea Garolla, Margherita Scapin, ...
Phospholipid hydroperoxide glutathione peroxidase (PHGPx), the product of gpx-4, is the major selenoprotein in sperm and is considered essential for fertilization because of its multiple roles in...
Carlo Foresta, Leopold Flohé, Andrea Garolla, Antonella Roveri, Fulvio Ursini, Matilde Maiorino
The selenoprotein phospholipid hydroperoxide glutathione peroxidase (PHGPx) accounts for almost the entire selenium content of mammalian testis. PHGPx is abundantly expressed in spermatids as active...
Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues.
Schomburg, Lutz, Schweizer, Ulrich, Holtmann, Bettina, Flohé, Leopold, Sendtner, Michael, Köhrle, Josef
Selenoprotein P (SePP), the major selenoprotein in plasma, has been implicated in selenium transport, selenium detoxification or antioxidant defence. We generated SePP-knockout mice that were viable,...
Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues.
Schomburg, Lutz, Schweizer, Ulrich, Holtmann, Bettina, Flohé, Leopold, Sendtner, Michael, Köhrle, Josef
Selenoprotein P (SePP), the major selenoprotein in plasma, has been implicated in selenium transport, selenium detoxification or antioxidant defence. We generated SePP-knockout mice that were viable,...
Comini, Marcelo A., Krauth-Siegel, R. Luise, Flohé, Leopold
In trypanosomes, the thioredoxin-type protein TXN (tryparedoxin) is a multi-purpose oxidoreductase that is involved in the detoxification of hydroperoxides, the synthesis of DNA precursors and the...