Furge, Kyle A, Dykema, Karl J, Ho, Coral, Chen, Xin
Abstract Background Regional expression biases (REBs) are genetic intervals where gene expression is coordinately changed. For example, if a region of the genome is amplified, often the majority of...
Crawley, Joseph J, Furge, Kyle A
Abstract Background Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. Frequent cytogenetic abnormalities that occur in HCC suggest that tumor-modifying genes (oncogenes or tumor...
Thesis (Ph. D.)--Vanderbilt University, 2000.
Takahashi, Masayuki, Rhodes, Daniel R., Furge, Kyle A., Kanayama, Hiro-omi, Kagawa, Susumu, Haab, Brian B., ...
To better understand the molecular mechanisms that underlie the tumorigenesis and progression of clear cell renal cell carcinoma (ccRCC), we studied the gene expression profiles of 29 ccRCC tumors...
Furge, Kyle A., Kiewlich, David, Le, Phuong, Vo, My Nga, Faure, Michel, Howlett, Anthony R., ...
Mutations in the Ras family of GTP binding proteins represent one of the most frequently observed genetic alterations in human cancers. We and others have recently demonstrated that expression of...
Crawley, Joseph J, Furge, Kyle A
Using comparative genomic microarray analysis (CGMA), 104 hepatocellular carcinoma (HCC) gene-expression microarray profiles were analyzed. CGMA identified 13 regions of frequent cytogenetic change...
Takahashi, Masayuki, Rhodes, Daniel R., Furge, Kyle A., Kanayama, Hiro-omi, Kagawa, Susumu, Haab, Brian B., ...
To better understand the molecular mechanisms that underlie the tumorigenesis and progression of clear cell renal cell carcinoma (ccRCC), we studied the gene expression profiles of 29 ccRCC tumors...
Furge, Kyle A., Kiewlich, David, Le, Phuong, Vo, My Nga, Faure, Michel, Howlett, Anthony R., ...
Mutations in the Ras family of GTP binding proteins represent one of the most frequently observed genetic alterations in human cancers. We and others have recently demonstrated that expression of...
Crawley, Joseph J, Furge, Kyle A
Using comparative genomic microarray analysis (CGMA), 104 hepatocellular carcinoma (HCC) gene-expression microarray profiles were analyzed. CGMA identified 13 regions of frequent cytogenetic change...
Furge, Kyle A, Dykema, Karl, Petillo, David, Westphal, Michael, Zhang, Zhongfa, Kort, Eric J, ...
Using high-throughput gene-expression profiling technology, we can now gain a better understanding of the complex biology that is taking place in cancer cells. This complexity is largely dictated by...
Koeman, Julie M., Russell, Ryan C., Tan, Min-Han, Petillo, David, Westphal, Michael, Koelzer, Katherine, ...
Chromosomal abnormalities, such as structural and numerical abnormalities, are a common occurrence in cancer. The close association of homologous chromosomes during interphase, a phenomenon termed...