Kristen M. Lockridge

Pathogenesis of Experimental Rhesus Cytomegalovirus Infection

Lockridge, Kristen M., Sequar, Getachew, Zhou, Shan Shan, Yue, Yujuan, Mandell, Carol P., Barry, Peter A.

Human cytomegalovirus (HCMV) establishes and maintains a lifelong persistence following infection in an immunocompetent host. The determinants of a stable virus-host relationship are poorly defined....

Construction and In Vitro Characterization of Attenuated Feline Immunodeficiency Virus Long Terminal Repeat Mutant Viruses

Bigornia, Luisa, Lockridge, Kristen M., Sparger, Ellen E.

AP-1- and ATF-binding sites are cis-acting transcriptional elements within the U3 domain of the feline immunodeficiency virus (FIV) long terminal repeat (LTR) that serve as targets for cellular...

Potent Immunosuppressive Activities of Cytomegalovirus- Encoded Interleukin-10

Spencer, Juliet V., Lockridge, Kristen M., Barry, Peter A., Lin, Gaofeng, Tsang, Monica, Penfold, Mark E. T., ...

Cytomegalovirus (CMV) has highly evolved mechanisms for avoiding detection by the host immune system. Recently, in the genomes of human and primate CMV, a novel gene comprising segments of...

Experimental Coinfection of Rhesus Macaques with Rhesus Cytomegalovirus and Simian Immunodeficiency Virus: Pathogenesis

Sequar, Getachew, Britt, William J., Lakeman, Fred D., Lockridge, Kristen M., Tarara, Ross P., Canfield, Don R., ...

Human cytomegalovirus (HCMV) possesses low pathogenic potential in an immunocompetent host. In the immunosuppressed host, however, a wide spectrum of infection outcomes, ranging from asymptomatic to...

Pathogenesis of Experimental Rhesus Cytomegalovirus Infection

Lockridge, Kristen M., Sequar, Getachew, Zhou, Shan Shan, Yue, Yujuan, Mandell, Carol P., Barry, Peter A.

Human cytomegalovirus (HCMV) establishes and maintains a lifelong persistence following infection in an immunocompetent host. The determinants of a stable virus-host relationship are poorly defined....

Construction and In Vitro Characterization of Attenuated Feline Immunodeficiency Virus Long Terminal Repeat Mutant Viruses

Bigornia, Luisa, Lockridge, Kristen M., Sparger, Ellen E.

AP-1- and ATF-binding sites are cis-acting transcriptional elements within the U3 domain of the feline immunodeficiency virus (FIV) long terminal repeat (LTR) that serve as targets for cellular...

Potent Immunosuppressive Activities of Cytomegalovirus- Encoded Interleukin-10

Spencer, Juliet V., Lockridge, Kristen M., Barry, Peter A., Lin, Gaofeng, Tsang, Monica, Penfold, Mark E. T., ...

Cytomegalovirus (CMV) has highly evolved mechanisms for avoiding detection by the host immune system. Recently, in the genomes of human and primate CMV, a novel gene comprising segments of...

Experimental Coinfection of Rhesus Macaques with Rhesus Cytomegalovirus and Simian Immunodeficiency Virus: Pathogenesis

Sequar, Getachew, Britt, William J., Lakeman, Fred D., Lockridge, Kristen M., Tarara, Ross P., Canfield, Don R., ...

Human cytomegalovirus (HCMV) possesses low pathogenic potential in an immunocompetent host. In the immunosuppressed host, however, a wide spectrum of infection outcomes, ranging from asymptomatic to...