Kousaku Okubo

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004)

Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, Kanako O. Koyanagi, ...

An international team has systematically validated and annotated just over 21,000 human genes using full-length cDNA, thereby providing a valuable new resource for the human genetics community.

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004)

Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, Kanako O. Koyanagi, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

Integration of Diverse Knowledge and Data (2003)

Yoshimasa Tsuruoka, Teruyoshi Hishiki, Osamu Ogasawara, Kousaku Okubo

After the accomplishment of human draft sequence, more and more efforts are being made in the mapping of the data-driven patterns to background knowledge, hoping to efficiently produce hypotheses out...

Ordering Genes by significance of occurrences (2000)

Shinichi Morishita, Kousaku Okubo

This paper focuses on non-normalized mRNA library and we establish an index of finding di#erentially expressed genes. Then we might express that the genes ordering by using our statistical method in...

BodyMap incorporated PCR-based expression profiling data and a gene ranking system

Sese, Jun, Nikaidou, Hitoshi, Kawamoto, Shoko, Minesaki, Yuichi, Morishita, Shinichi, Okubo, Kousaku

BodyMap is a human and mouse gene expression database that is based on site-directed 3′-expressed sequence tags generated at Osaka University. To date, it contains more than 300 000 tag sequences...

BodyMap: a human and mouse gene expression database

Hishiki, Teruyoshi, Kawamoto, Shoko, Morishita, Shinichi, Okubo, Kousaku

BodyMap is a human and mouse gene expression database that has been maintained since 1993. It is based on site-directed 3′-ESTs collected from non-biased cDNA libraries constructed at Osaka...

BodyMap: A Collection of 3′ ESTs for Analysis of Human Gene Expression Information

Kawamoto, Shoko, Yoshii, Junji, Mizuno, Katsuya, Ito, Kouichi, Miyamoto, Yasuhide, Ohnishi, Tadashi, ...

BodyMap is a collection of site-directed 3′ expressed sequence tags (ESTs) (gene signatures, GSs) that contains the transcript compositions of various human tissues and was the first systematic...

Expression Profiling by iAFLP: A PCR-Based Method for Genome-Wide Gene Expression Profiling

Kawamoto, Shoko, Ohnishi, Tadashi, Kita, Hiroko, Chisaka, Osamu, Okubo, Kousaku

The availability of comprehensive sets of genes has prompted the researchers to carry out systematic collection of gene expression data. RT–PCR has the highest specificity and sensitivity for...

Identification and Characterization of the Potential Promoter Regions of 1031 Kinds of Human Genes

Suzuki, Yutaka, Tsunoda, Tatsuhiko, Sese, Jun, Taira, Hirotoshi, Mizushima-Sugano, Junko, Hata, Hiroko, ...

To understand the mechanism of transcriptional regulation, it is essential to identify and characterize the promoter, which is located proximal to the mRNA start site. To identify the promoters from...

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Imanishi, Tadashi, Itoh, Takeshi, Suzuki, Yutaka, O'Donovan, Claire, Fukuchi, Satoshi, Koyanagi, Kanako O, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

The Human Anatomic Gene Expression Library (H-ANGEL), the H-Inv integrative display of human gene expression across disparate technologies and platforms

Tanino, Motohiko, Debily, Marie-Anne, Tamura, Takuro, Hishiki, Teruyoshi, Ogasawara, Osamu, Murakawa, Katsuji, ...

The Human Anatomic Gene Expression Library (H-ANGEL) is a resource for information concerning the anatomical distribution and expression of human gene transcripts. The tool contains protein...

Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites

Suzuki, Yutaka, Taira, Hirotoshi, Tsunoda, Tatsuhiko, Mizushima-Sugano, Junko, Sese, Jun, Hata, Hiroko, ...

Determination of the mRNA start site is the first step in identifying the promoter region, which is of key importance for transcriptional regulation of gene expression. The ‘oligo-capping’ method...

DDBJ in preparation for overview of research activities behind data submissions

Okubo, Kousaku, Sugawara, Hideaki, Gojobori, Takashi, Tateno, Yoshio

In the past year, DDBJ () collected and released 1 956 826 entries or 1 741 313 111 bases. The released data include ∼90 000 ESTs and cDNAs of Macaca fascicularis, and 280 million bases of mouse...

BodyMap-Xs: anatomical breakdown of 17 million animal ESTs for cross-species comparison of gene expression

Ogasawara, Osamu, Otsuji, Makiko, Watanabe, Kouji, Iizuka, Takayasu, Tamura, Takuro, Hishiki, Teruyoshi, ...

BodyMap-Xs () is a database for cross-species gene expression comparison. It was created by the anatomical breakdown of 17 million animal expressed sequence tag (EST) records in DDBJ using a sorting...

BodyMap incorporated PCR-based expression profiling data and a gene ranking system

Sese, Jun, Nikaidou, Hitoshi, Kawamoto, Shoko, Minesaki, Yuichi, Morishita, Shinichi, Okubo, Kousaku

BodyMap is a human and mouse gene expression database that is based on site-directed 3′-expressed sequence tags generated at Osaka University. To date, it contains more than 300 000 tag sequences...

BodyMap: a human and mouse gene expression database

Hishiki, Teruyoshi, Kawamoto, Shoko, Morishita, Shinichi, Okubo, Kousaku

BodyMap is a human and mouse gene expression database that has been maintained since 1993. It is based on site-directed 3′-ESTs collected from non-biased cDNA libraries constructed at Osaka...

BodyMap: A Collection of 3′ ESTs for Analysis of Human Gene Expression Information

Kawamoto, Shoko, Yoshii, Junji, Mizuno, Katsuya, Ito, Kouichi, Miyamoto, Yasuhide, Ohnishi, Tadashi, ...

BodyMap is a collection of site-directed 3′ expressed sequence tags (ESTs) (gene signatures, GSs) that contains the transcript compositions of various human tissues and was the first systematic...

Expression Profiling by iAFLP: A PCR-Based Method for Genome-Wide Gene Expression Profiling

Kawamoto, Shoko, Ohnishi, Tadashi, Kita, Hiroko, Chisaka, Osamu, Okubo, Kousaku

The availability of comprehensive sets of genes has prompted the researchers to carry out systematic collection of gene expression data. RT–PCR has the highest specificity and sensitivity for...

Identification and Characterization of the Potential Promoter Regions of 1031 Kinds of Human Genes

Suzuki, Yutaka, Tsunoda, Tatsuhiko, Sese, Jun, Taira, Hirotoshi, Mizushima-Sugano, Junko, Hata, Hiroko, ...

To understand the mechanism of transcriptional regulation, it is essential to identify and characterize the promoter, which is located proximal to the mRNA start site. To identify the promoters from...

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Imanishi, Tadashi, Itoh, Takeshi, Suzuki, Yutaka, O'Donovan, Claire, Fukuchi, Satoshi, Koyanagi, Kanako O, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

The Human Anatomic Gene Expression Library (H-ANGEL), the H-Inv integrative display of human gene expression across disparate technologies and platforms

Tanino, Motohiko, Debily, Marie-Anne, Tamura, Takuro, Hishiki, Teruyoshi, Ogasawara, Osamu, Murakawa, Katsuji, ...

The Human Anatomic Gene Expression Library (H-ANGEL) is a resource for information concerning the anatomical distribution and expression of human gene transcripts. The tool contains protein...

Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites

Suzuki, Yutaka, Taira, Hirotoshi, Tsunoda, Tatsuhiko, Mizushima-Sugano, Junko, Sese, Jun, Hata, Hiroko, ...

Determination of the mRNA start site is the first step in identifying the promoter region, which is of key importance for transcriptional regulation of gene expression. The ‘oligo-capping’ method...

DDBJ in preparation for overview of research activities behind data submissions

Okubo, Kousaku, Sugawara, Hideaki, Gojobori, Takashi, Tateno, Yoshio

In the past year, DDBJ () collected and released 1 956 826 entries or 1 741 313 111 bases. The released data include ∼90 000 ESTs and cDNAs of Macaca fascicularis, and 280 million bases of mouse...

BodyMap-Xs: anatomical breakdown of 17 million animal ESTs for cross-species comparison of gene expression

Ogasawara, Osamu, Otsuji, Makiko, Watanabe, Kouji, Iizuka, Takayasu, Tamura, Takuro, Hishiki, Teruyoshi, ...

BodyMap-Xs () is a database for cross-species gene expression comparison. It was created by the anatomical breakdown of 17 million animal expressed sequence tag (EST) records in DDBJ using a sorting...

Cornichon-like Protein Facilitates Secretion of HB-EGF and Regulates Proper Development of Cranial Nerves

Hoshino, Hideharu, Uchida, Tsukasa, Otsuki, Toshiaki, Kawamoto, Shoko, Okubo, Kousaku, Takeichi, Masatoshi, ...

During their migration to the periphery, cranial neural crest cells (NCCs) are repulsed by an ErbB4-dependent cue(s) in the mesenchyme adjoining rhombomeres (r) 3 and 5, which are segmented hindbrain...