MicroRNA-155 is induced during the macrophage inflammatory response (2007)
O'Connell, Ryan M., Taganov, Konstantin D., Boldin, Mark P., Cheng, Genhong, Baltimore, David
The mammalian inflammatory response to infection involves the induction of several hundred genes, a process that must be carefully regulated to achieve pathogen clearance and prevent the consequences...
Taganov, Konstantin D., Boldin, Mark P., Chang, Kuang-Jung, Baltimore, David
Activation of mammalian innate and acquired immune responses must be tightly regulated by elaborate mechanisms to control their onset and termination. MicroRNAs have been implicated as negative...
Genome-Wide Analyses of Avian Sarcoma Virus Integration Sites (2004)
Narezkina, Anna, Taganov, Konstantin D., Litwin, Samuel, Stoyanova, Radka, Hayashi, Junpei, Seeger, Christoph, ...
The chromosomal features that influence retroviral integration site selection are not well understood. Here, we report the mapping of 226 avian sarcoma virus (ASV) integration sites in the human...
Daniel, René, Ramcharan, Joseph, Rogakou, Emmy, Taganov, Konstantin D., Greger, James G., Bonner, William, ...
The histone variant H2AX is rapidly phosphorylated (denoted {gamma}H2AX) in large chromatin domains (foci) flanking double strand DNA (dsDNA) breaks that are produced by ionizing radiation or...
Taganov, Konstantin D., Cuesta, Isabel, Daniel, René, Cirillo, Lisa Ann, Katz, Richard A., Zaret, Kenneth S., ...
Integration of viral DNA into the host chromosome is an obligatory step in retroviral replication and is dependent on the activity of the viral enzyme integrase. To examine the influence of chromatin...
Taganov, Konstantin D., Cuesta, Isabel, Daniel, René, Cirillo, Lisa Ann, Katz, Richard A., Zaret, Kenneth S., ...
Integration of viral DNA into the host chromosome is an obligatory step in retroviral replication and is dependent on the activity of the viral enzyme integrase. To examine the influence of chromatin...
Daniel, René, Greger, James G., Katz, Richard A., Taganov, Konstantin D., Wu, Xiaoyun, Kappes, John C., ...
We have previously reported several lines of evidence that support a role for cellular DNA repair systems in completion of the retroviral DNA integration process. Failure to repair an intermediate in...
Genome-Wide Analyses of Avian Sarcoma Virus Integration Sites
Narezkina, Anna, Taganov, Konstantin D., Litwin, Samuel, Stoyanova, Radka, Hayashi, Junpei, Seeger, Christoph, ...
The chromosomal features that influence retroviral integration site selection are not well understood. Here, we report the mapping of 226 avian sarcoma virus (ASV) integration sites in the human...
Taganov, Konstantin D., Cuesta, Isabel, Daniel, René, Cirillo, Lisa Ann, Katz, Richard A., Zaret, Kenneth S., ...
Integration of viral DNA into the host chromosome is an obligatory step in retroviral replication and is dependent on the activity of the viral enzyme integrase. To examine the influence of chromatin...
Daniel, René, Greger, James G., Katz, Richard A., Taganov, Konstantin D., Wu, Xiaoyun, Kappes, John C., ...
We have previously reported several lines of evidence that support a role for cellular DNA repair systems in completion of the retroviral DNA integration process. Failure to repair an intermediate in...
Genome-Wide Analyses of Avian Sarcoma Virus Integration Sites
Narezkina, Anna, Taganov, Konstantin D., Litwin, Samuel, Stoyanova, Radka, Hayashi, Junpei, Seeger, Christoph, ...
The chromosomal features that influence retroviral integration site selection are not well understood. Here, we report the mapping of 226 avian sarcoma virus (ASV) integration sites in the human...
Taganov, Konstantin D., Boldin, Mark P., Chang, Kuang-Jung, Baltimore, David
Activation of mammalian innate and acquired immune responses must be tightly regulated by elaborate mechanisms to control their onset and termination. MicroRNAs have been implicated as negative...
MicroRNA-155 is induced during the macrophage inflammatory response
O'Connell, Ryan M., Taganov, Konstantin D., Boldin, Mark P., Cheng, Genhong, Baltimore, David
The mammalian inflammatory response to infection involves the induction of several hundred genes, a process that must be carefully regulated to achieve pathogen clearance and prevent the consequences...
O'Connell, Ryan M., Rao, Dinesh S., Chaudhuri, Aadel A., Boldin, Mark P., Taganov, Konstantin D., Nicoll, John, ...
Mammalian microRNAs are emerging as key regulators of the development and function of the immune system. Here, we report a strong but transient induction of miR-155 in mouse bone marrow after...