Klas Blomgren

Mitochondrial Cell Death Control in Familial Parkinson Disease (2007)

Guido Kroemer, Klas Blomgren

Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis-inducing factor, cytochrome c and caspase-3 activation in neurons exposed to transient hypoglycemia. (2003)

Ferrand-Drake, Michel, Zhu, Changlian, Gidö, Gunilla, Hansen, Anker J, Karlsson, Jan-Olof, Bahr, Ben A, ...

Abstract is not available

Death mechanisms in status epilepticus-generated neurons and effects of additional seizures on their survival. (2003)

Ekdahl, Christine T, Zhu, Changlian, Bonde, Sara, Bahr, Ben A, Blomgren, Klas, Lindvall, Olle

Abstract is not available

Caspase-mediated death of newly formed neurons in the adult rat dentate gyrus following status epilepticus. (2002)

Ekdahl, Christine T., Mohapel, Paul, Weber, Ekkehard, Bahr, Ben, Blomgren, Klas, Lindvall, Olle

A large proportion of cells that proliferate in the adult dentate gyrus under normal conditions or in response to brain insults exhibit only short-term survival. Here, we sought to determine which...

Mitochondrial Cell Death Control in Familial Parkinson Disease

Kroemer, Guido, Blomgren, Klas

Many sporadic cases of Parkinsons disease have mutations in the PINK protein kinase, whose substrate is now revealed to be a protein that protects mitochondria from oxidative stress.

Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia

Zhu, Changlian, Wang, Xiaoyang, Deinum, Johanna, Huang, Zhiheng, Gao, Jianfeng, Modjtahedi, Nazanine, ...

Upon cerebral hypoxia-ischemia (HI), apoptosis-inducing factor (AIF) can move from mitochondria to nuclei, participate in chromatinolysis, and contribute to the execution of cell death. Previous work...