Kiyokazu Agata

The innate immune repertoire in Cnidaria - ancestral complexity and stochastic gene loss (2007)

Miller, David J, Hemmrich, Georg, Ball, Eldon E, Hayward, David C, Khalturin, Konstantin, Funayama, Noriko, ...

Abstract Background Characterization of the innate immune repertoire of extant cnidarians is of both fundamental and applied interest - it not only provides insights into the basic immunological...

The innate immune repertoire in Cnidaria - ancestral complexity and stochastic gene loss (2007)

Miller, David James, Hemmrich, Georg, Ball, Eldon E., Hayward, David C., Khalturin, Konstantin, Funayama, Noriko, ...

© 2007 Miller et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License...

The innate immune repertoire in Cnidaria - ancestral complexity and stochastic gene loss (2007)

Miller, David James, Hemmrich, Georg, Ball, Eldon E., Hayward, David C., Khalturin, Konstantin, Funayama, Noriko, ...

© 2007 Miller et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License...

Evidence for different origin of sex chromosomes in snakes, birds, and mammals and step-wise differentiation of snake sex chromosomes. (2006)

Matsubara, Kazumi, Tarui, Hiroshi, Toriba, Michihisa, Yamada, Kazuhiko, Nishida-Umehara, Chizuko, Agata, Kiyokazu, ...

All snake species exhibit genetic sex determination with the ZZ/ZW type of sex chromosomes. To investigate the origin and evolution of snake sex chromosomes, we constructed, by FISH, a cytogenetic...

cDNA-based gene mapping and GC3 profiling in the soft-shelled turtle suggest a chromosomal size-dependent GC bias shared by sauropsids (2006)

Kuraku, Shigehiro, Ishijima, Junko, Nishida-Umehara, Chizuko, Agata, Kiyokazu, Kuratani, Shigeru, Matsuda, Yoichi

Mammalian and avian genomes comprise several classes of chromosomal segments that vary dramatically in GC-content. Especially in chicken, microchromosomes exhibit a higher GC-content and a higher...

Isolation of Ef silicatein and Ef lectin as molecular markers for sclerocytes and cells involved in innate immunity in the freshwater sponge Ephydatia fluviatilis (2005)

Funayama, Noriko, Nakatsukasa, Mikiko, Kuraku, Shigehiro, Takechi, Katsuaki, Dohi, Mikako, Iwabe, Naoyuki, ...

Sponges (phylum Porifera) have remarkable regenerative and reconstitutive abilities and represent evolutionarily the oldest metazoans. To investigate sponge stem cell differentiation, we have focused...

Highly conserved linkage homology between birds and turtles: Bird and turtle chromosomes are precise counterparts of each other (2005)

Matsuda, Yoichi, Nishida-Umehara, Chizuko, Tarui, Hiroshi, Kuroiwa, Asato, Yamada, Kazuhiko, Isobe, Taku, ...

The karyotypes of birds, turtles and snakes are characterized by two distinct chromosomal components, macrochromosomes and microchromosomes. This close karyological relationship between birds and...

Purification and cDNA cloning of the ovigerous-hair stripping substance (OHSS) contained in the hatch water of an estuarine crab Sesarma haematocheir (2003)

Gusev, Oleg, Ikeda, Hideki, Okochi, Tetsushi, Lee, Jae Min, Hatakeyama, Masatsugu, Kobayashi, Chiyoko, ...

The egg attachment system of an estuarine crab Sesarma haematocheir is formed on the maternal ovigerous hairs just after egg laying, and slips off these hairs just after hatching. The stripping is...

Organization and Regeneration Ability of Spontaneous Supernumerary Eyes in Planarians —Eye Regeneration Field and Pathway Selection by Optic Nerves— (2000)

Fumie Sakai, Kiyokazu Agata, Hidefumi Orii, Kenji Watanabe

Planarians can propagate asexually by fission and successive regeneration. During head regeneration, they again form a new pair of eyes, and sometimes supernumerary eyes. The positions of normal and...

Identification of Two Distinct Muscles in the Planarian Dugesia japonica by their Expression of Myosin Heavy Chain Genes (1998)

Chiyoko Kobayashi, Seitaro Kobayashi, Hidefumi Orii, Kenji Watanabe, Kiyokazu Agata

Ultrastructural and physiological studies have shown that planarian muscles have some characteristics of smooth and some characteristics of striated muscles. To characterize planarian muscles, we...

Molecular Cloning of Bone Morphogenetic Protein (BMP) Gene from the Planarian Dugesia japonica (1998)

Hidefumi Orii, Kentaro Kato, Kiyokazu Agata, Kenji Watanabe

BMP (Bone Morphogenetic Protein) acts as a morphogen for dorso-ventral patterning and organogenesis in both vertebrate and invertebrate development. A cDNA encoding BMP (named Djbmp) has been cloned...

Identification of Two Distinct Muscles in the Planarian Dugesia japonica by their Expression of Myosin Heavy Chain Genes (1998)

Chiyoko Kobayashi, Seitaro Kobayashi, Hidefumi Orii, Kenji Watanabe, Kiyokazu Agata

Ultrastructural and physiological studies have shown that planarian muscles have some characteristics of smooth and some characteristics of striated muscles. To characterize planarian muscles, we...

Molecular Cloning of Bone Morphogenetic Protein (BMP) Gene from the Planarian Dugesia japonica (1998)

Hidefumi Orii, Kentaro Kato, Kiyokazu Agata, Kenji Watanabe

BMP (Bone Morphogenetic Protein) acts as a morphogen for dorso-ventral patterning and organogenesis in both vertebrate and invertebrate development. A cDNA encoding BMP (named Djbmp) has been cloned...

Structure of the Planarian Central Nervous System (CNS) Revealed by Neuronal Cell Markers (1998)

Kiyokazu Agata, Yukihiro Soejima, Kentaro Kato, Chiyoko Kobayashi, Yoshihiko Umesono, Kenji Watanabe

Planarians are considered to be among the most primitive animals which developed the central nervous system (CNS). To understand the origin and evolution of the CNS, we have isolated a neural marker...

Identification of a photoreceptor cell-specific nuclear receptor

Kobayashi, Mime, Takezawa, Shin-ichiro, Hara, Kenji, Yu, Ruth T., Umesono, Yoshihiko, Agata, Kiyokazu, ...

Nuclear receptors comprise a large and expanding family of transcription factors involved in diverse aspects of animal physiology and development, the functions of which can be modulated in a spatial...

Origin and evolutionary process of the CNS elucidated by comparative genomics analysis of planarian ESTs

Mineta, Katsuhiko, Nakazawa, Masumi, Cebrià, Francesc, Ikeo, Kazuho, Agata, Kiyokazu, Gojobori, Takashi

Among the bilateral animals, a centralized nervous system is found in both the deuterostome and protostome. To address the question of whether the CNS was derived from a common ancestor of...

Seasonal Change in Bacterial Flora and Biomass in Mountain Snow from the Tateyama Mountains, Japan, Analyzed by 16S rRNA Gene Sequencing and Real-Time PCR

Segawa, Takahiro, Miyamoto, Koji, Ushida, Kazunari, Agata, Kiyokazu, Okada, Norihiro, Kohshima, Shiro

The bacterial flora and biomass in mountain snow from the Tateyama Mountains, Toyama Prefecture, Japan, one of the heaviest snowfall regions in the world, were analyzed by amplified ribosomal DNA...

Identification of a photoreceptor cell-specific nuclear receptor

Kobayashi, Mime, Takezawa, Shin-ichiro, Hara, Kenji, Yu, Ruth T., Umesono, Yoshihiko, Agata, Kiyokazu, ...

Nuclear receptors comprise a large and expanding family of transcription factors involved in diverse aspects of animal physiology and development, the functions of which can be modulated in a spatial...

Origin and evolutionary process of the CNS elucidated by comparative genomics analysis of planarian ESTs

Mineta, Katsuhiko, Nakazawa, Masumi, Cebrià, Francesc, Ikeo, Kazuho, Agata, Kiyokazu, Gojobori, Takashi

Among the bilateral animals, a centralized nervous system is found in both the deuterostome and protostome. To address the question of whether the CNS was derived from a common ancestor of...

Seasonal Change in Bacterial Flora and Biomass in Mountain Snow from the Tateyama Mountains, Japan, Analyzed by 16S rRNA Gene Sequencing and Real-Time PCR

Segawa, Takahiro, Miyamoto, Koji, Ushida, Kazunari, Agata, Kiyokazu, Okada, Norihiro, Kohshima, Shiro

The bacterial flora and biomass in mountain snow from the Tateyama Mountains, Toyama Prefecture, Japan, one of the heaviest snowfall regions in the world, were analyzed by amplified ribosomal DNA...

Evidence for different origin of sex chromosomes in snakes, birds, and mammals and step-wise differentiation of snake sex chromosomes

Matsubara, Kazumi, Tarui, Hiroshi, Toriba, Michihisa, Yamada, Kazuhiko, Nishida-Umehara, Chizuko, Agata, Kiyokazu, ...

All snake species exhibit genetic sex determination with the ZZ/ZW type of sex chromosomes. To investigate the origin and evolution of snake sex chromosomes, we constructed, by FISH, a cytogenetic...

The innate immune repertoire in Cnidaria - ancestral complexity and stochastic gene loss

Miller, David J, Hemmrich, Georg, Ball, Eldon E, Hayward, David C, Khalturin, Konstantin, Funayama, Noriko, ...

Analysis of genomic resources available for cnidarians revealed that several key components of the vertebrate innate immune repertoire are present in representatives of the basal cnidarian class...