Most organisms initiate meiotic recombination with the formation of double strand breaks (DSB). Drosophila females, however, are among the group of organisms where synaptonemal complex (SC) formation...
Wei J. Gong, Kim S. McKim, R. Scott Hawley
The multiply inverted X chromosome balancer FM7 strongly suppresses, or eliminates, the occurrence of crossing over when heterozygous with a normal sequence homolog. We have utilized the LacI-GFP:...
Anderson, Lorinda K., Royer, Suzanne M., Page, Scott L., McKim, Kim S., Lai, Ann, Lilly, Mary A., ...
The synaptonemal complex (SC) is intimately involved in the process of meiotic recombination in most organisms, but its exact role remains enigmatic. One reason for this uncertainty is that the...
Anderson, Lorinda K., Royer, Suzanne M., Page, Scott L., McKim, Kim S., Lai, Ann, Lilly, Mary A., ...
The synaptonemal complex (SC) is intimately involved in the process of meiotic recombination in most organisms, but its exact role remains enigmatic. One reason for this uncertainty is that the...
Manheim, Elizabeth A., Jang, Janet K., Dominic, Danielle, McKim, Kim S.
During Drosophila oogenesis, the oocyte is formed within a 16-cell cyst immediately after four incomplete cell divisions. One of the primary events in oocyte development is meiotic recombination....
McKim, Kim S., Hayashi-Hagihara, Aki
Meiotic recombination requires the action of several gene products in both Saccharomyces cerevisiae and Drosophila melanogaster. Genetic studies in D. melanogaster have shown that the mei-W68 gene is...
Anderson, Lorinda K., Royer, Suzanne M., Page, Scott L., McKim, Kim S., Lai, Ann, Lilly, Mary A., ...
The synaptonemal complex (SC) is intimately involved in the process of meiotic recombination in most organisms, but its exact role remains enigmatic. One reason for this uncertainty is that the...
All Paired Up with No Place to Go: Pairing, Synapsis, and DSB Formation in a Balancer Heterozygote
Gong, Wei J, McKim, Kim S, Hawley, R. Scott
The multiply inverted X chromosome balancer FM7 strongly suppresses, or eliminates, the occurrence of crossing over when heterozygous with a normal sequence homolog. We have utilized the LacI-GFP:...
Sherizen, Dalia, Jang, Janet K., Bhagat, Rajal, Kato, Naohiro, McKim, Kim S.
In the pairing-site model, specialized regions on each chromosome function to establish meiotic homolog pairing. Analysis of these sites could provide insights into the mechanism used by Drosophila...
Giunta, Kelly L, Jang, Janet K, Manheim, Elizabeth A, Subramanian, Gayathri, McKim, Kim S
The female meiotic spindle lacks a centrosome or microtubule-organizing center in many organisms. During cell division, these spindles are organized by the chromosomes and microtubule-associated...
Liu, Hao, Jang, Janet K, Kato, Naohiro, McKim, Kim S
Double-strand breaks (DSB) initiate meiotic recombination in a variety of organisms. Here we present genetic evidence that the mei-P22 gene is required for the induction of DSBs during meiotic...
Manheim, Elizabeth A., Jang, Janet K., Dominic, Danielle, McKim, Kim S.
During Drosophila oogenesis, the oocyte is formed within a 16-cell cyst immediately after four incomplete cell divisions. One of the primary events in oocyte development is meiotic recombination....
McKim, Kim S., Hayashi-Hagihara, Aki
Meiotic recombination requires the action of several gene products in both Saccharomyces cerevisiae and Drosophila melanogaster. Genetic studies in D. melanogaster have shown that the mei-W68 gene is...
Anderson, Lorinda K., Royer, Suzanne M., Page, Scott L., McKim, Kim S., Lai, Ann, Lilly, Mary A., ...
The synaptonemal complex (SC) is intimately involved in the process of meiotic recombination in most organisms, but its exact role remains enigmatic. One reason for this uncertainty is that the...
All Paired Up with No Place to Go: Pairing, Synapsis, and DSB Formation in a Balancer Heterozygote
Gong, Wei J, McKim, Kim S, Hawley, R. Scott
The multiply inverted X chromosome balancer FM7 strongly suppresses, or eliminates, the occurrence of crossing over when heterozygous with a normal sequence homolog. We have utilized the LacI-GFP:...
Sherizen, Dalia, Jang, Janet K., Bhagat, Rajal, Kato, Naohiro, McKim, Kim S.
In the pairing-site model, specialized regions on each chromosome function to establish meiotic homolog pairing. Analysis of these sites could provide insights into the mechanism used by Drosophila...
Giunta, Kelly L, Jang, Janet K, Manheim, Elizabeth A, Subramanian, Gayathri, McKim, Kim S
The female meiotic spindle lacks a centrosome or microtubule-organizing center in many organisms. During cell division, these spindles are organized by the chromosomes and microtubule-associated...
Liu, Hao, Jang, Janet K, Kato, Naohiro, McKim, Kim S
Double-strand breaks (DSB) initiate meiotic recombination in a variety of organisms. Here we present genetic evidence that the mei-P22 gene is required for the induction of DSBs during meiotic...
Jang, Janet K., Rahman, Taslima, Kober, Vanessa S., Cesario, Jeffry, McKim, Kim S.
Bipolar spindles assemble in the absence of centrosomes in the oocytes of many species. In Drosophila melanogaster oocytes, the chromosomes have been proposed to initiate spindle assembly by...
mei-38 Is Required for Chromosome Segregation During Meiosis in Drosophila Females
Wu, Changjian, Singaram, Vinod, McKim, Kim S.
Meiotic chromosome segregation occurs in Drosophila oocytes on an acentrosomal spindle, which raises interesting questions regarding spindle assembly and function. One is how to organize a bipolar...