Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle
Rosenberg, Mark F., Velarde, Giles, Ford, Robert C., Martin, Catherine, Berridge, Georgina, Kerr, Ian D., ...
P-glycoprotein (P-gp) is an ABC (ATP-binding cassette) transporter, which hydrolyses ATP and extrudes cytotoxic drugs from mammalian cells. P-gp consists of two transmembrane domains (TMDs) that span...
Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle
Rosenberg, Mark F., Velarde, Giles, Ford, Robert C., Martin, Catherine, Berridge, Georgina, Kerr, Ian D., ...
P-glycoprotein (P-gp) is an ABC (ATP-binding cassette) transporter, which hydrolyses ATP and extrudes cytotoxic drugs from mammalian cells. P-gp consists of two transmembrane domains (TMDs) that span...
Taylor, Andrew M, Storm, Janet, Soceneantu, Loredana, Linton, Kenneth J, Gabriel, Mark, Martin, Catherine, ...
Subtle alterations in the coupling of drug binding to nucleotide hydrolysis were observed following mutation of all seven endogenous cysteine residues to serines in the human multidrug resistance...
Martin, Catherine A., Longman, Emma, Wooding, Carol, Hoosdally, Sarah J., Ali, Saira, Aitman, Timothy J., ...
Cd36 is a small-molecular-weight integral membrane protein expressed in a diverse, but select, range of cell types. It has an equally diverse range of ligands and physiological functions, which has...