Comparison of human B cell activation by TLR7 and TLR9 agonists (2008)
Hanten, John A, Vasilakos, John P, Riter, Christie L, Neys, Lori, Lipson, Kenneth E, Alkan, Sefik S, ...
Abstract Background Human B cells and plasmacytoid dendritic cells (pDC) are the only cells known to express both TLR7 and TLR9. Plasmacytoid dendritic cells are the primary IFN-α producing cells in...
Birmachu, Woubalem, Gleason, Raymond M, Bulbulian, Barbara J, Riter, Christie L, Vasilakos, John P, Lipson, Kenneth E, ...
Abstract Background Plasmacytoid Dendritic Cells (pDC) comprise approximately 0.2 to 0.8% of the blood mononuclear cells and are the primary type 1 interferon (IFN), producing cells, secreting high...
Li, Minglun, Ping, Gong, Plathow, Christian, Trinh, Thuy, Lipson, Kenneth E, Hauser, Kai, ...
Abstract Background Several small receptor tyrosine kinase inhibitors (RTKI) have entered clinical cancer trials alone and in combination with radiotherapy or chemotherapy. The inhibitory spectrum of...
Furge, Kyle A., Kiewlich, David, Le, Phuong, Vo, My Nga, Faure, Michel, Howlett, Anthony R., ...
Mutations in the Ras family of GTP binding proteins represent one of the most frequently observed genetic alterations in human cancers. We and others have recently demonstrated that expression of...
Wright, Jocelyn H., Wang, Xueyan, Manning, Gerard, LaMere, Brandon J., Le, Phuong, Zhu, Shirley, ...
HGK (hepatocyte progenitor kinase-like/germinal center kinase-like kinase) is a member of the human STE20/mitogen-activated protein kinase kinase kinase kinase family of serine/threonine kinases and...
Lund, Eva L, Olsen, Minna W B, Lipson, Kenneth E, McMahon, Gerald, Howlett, Anthony R, Kristjansen, Paul E G
The effect of combining SU5416 with fractionated radiotherapy or with low molecular weight (LMW) heparin (dalteparin) was studied in U87 human glioblastoma xenografts in nude mice. SU5416 is...
Furge, Kyle A., Kiewlich, David, Le, Phuong, Vo, My Nga, Faure, Michel, Howlett, Anthony R., ...
Mutations in the Ras family of GTP binding proteins represent one of the most frequently observed genetic alterations in human cancers. We and others have recently demonstrated that expression of...
Wright, Jocelyn H., Wang, Xueyan, Manning, Gerard, LaMere, Brandon J., Le, Phuong, Zhu, Shirley, ...
HGK (hepatocyte progenitor kinase-like/germinal center kinase-like kinase) is a member of the human STE20/mitogen-activated protein kinase kinase kinase kinase family of serine/threonine kinases and...
Lund, Eva L, Olsen, Minna W B, Lipson, Kenneth E, McMahon, Gerald, Howlett, Anthony R, Kristjansen, Paul E G
The effect of combining SU5416 with fractionated radiotherapy or with low molecular weight (LMW) heparin (dalteparin) was studied in U87 human glioblastoma xenografts in nude mice. SU5416 is...
Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists
Birmachu, Woubalem, Gleason, Raymond M, Bulbulian, Barbara J, Riter, Christie L, Vasilakos, John P, Lipson, Kenneth E, ...
Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis
Abdollahi, Amir, Li, Minglun, Ping, Gong, Plathow, Christian, Domhan, Sophie, Kiessling, Fabian, ...
Pulmonary fibrosis is the consequence of a variety of diseases with no satisfying treatment option. Therapy-induced fibrosis also limits the efficacy of chemotherapy and radiotherapy in numerous...