Rhind, Shawn G., Rizoli, Sandro B., Shek, Pang N., Inaba, Kenji, Filips, Dennis, Tien, Homer, ...
Fluid resuscitation can often exacerbate injury sustained during hemorrhagic shock and is associated with altered immuno-inflammatory events. Early monocyte dysregulation and excessive...
Rhind, Shawn G., Rizoli, Sandro B., Shek, Pang N., Inaba, Kenji, Filips, Dennis, Tien, Homer, ...
Fluid resuscitation can often exacerbate injury sustained during hemorrhagic shock and is associated with altered immuno-inflammatory events. Early monocyte dysregulation and excessive...
Rizoli, Sandro B., Rhind, Shawn G., Shek, Pang N., Inaba, Kenji, Filips, Dennis, Tien, Homer, ...
Fluid resuscitation for traumatic hemorrhagic shock remains controversial since current protocols using large-volume crystalloid may exacerbate post-traumatic inflammation and organ dysfunction....
Paradoxical redox properties of DsbB and DsbA in the protein disulfide-introducing reaction cascade
Protein disulfide bond formation in the bacterial periplasm is catalyzed by the Dsb enzymes in conjunction with the respiratory quinone components. Here we characterized redox properties of the redox...
Inaba, Kenji, Takahashi, Yoh-hei, Ito, Koreaki, Hayashi, Shigehiko
Recent studies have revealed numerous examples in which oxidation and reduction of cysteines in proteins are integrated into specific cascades of biological regulatory systems. In general, these...
Rizoli, Sandro B., Rhind, Shawn G., Shek, Pang N., Inaba, Kenji, Filips, Dennis, Tien, Homer, ...
This is the first human trial demonstrating that hypertonic saline dextran (HSD) has immunologic and anti-inflammatory effects in trauma patients in hemorrhagic shock. HSD attenuated neutrophil...
Paradoxical redox properties of DsbB and DsbA in the protein disulfide-introducing reaction cascade
Protein disulfide bond formation in the bacterial periplasm is catalyzed by the Dsb enzymes in conjunction with the respiratory quinone components. Here we characterized redox properties of the redox...
Inaba, Kenji, Takahashi, Yoh-hei, Ito, Koreaki, Hayashi, Shigehiko
Recent studies have revealed numerous examples in which oxidation and reduction of cysteines in proteins are integrated into specific cascades of biological regulatory systems. In general, these...
Rizoli, Sandro B., Rhind, Shawn G., Shek, Pang N., Inaba, Kenji, Filips, Dennis, Tien, Homer, ...
This is the first human trial demonstrating that hypertonic saline dextran (HSD) has immunologic and anti-inflammatory effects in trauma patients in hemorrhagic shock. HSD attenuated neutrophil...
Selective Nonoperative Management of Penetrating Abdominal Solid Organ Injuries
Demetriades, Demetrios, Hadjizacharia, Pantelis, Constantinou, Costas, Brown, Carlos, Inaba, Kenji, Rhee, Peter, ...
This is a prospective study of 152 patients with 185 penetrating solid organ injuries. Overall, 41 patients (27.0%), including 18 cases with grade III or V injuries, were successfully managed without...
Protein disulfide bond generation in Escherichia coli DsbB–DsbA
The crystal structure of the DsbB–DsbA–ubiquinone ternary complex has revealed a mechanism of protein disulfide bond generation in Escherichia coli.