Kelly Stefano Cole

Common Themes of Antibody Maturation to Simian Immunodeficiency Virus, Simian-Human Immunodeficiency Virus, and Human Immunodeficiency Virus Type 1 Infections

Cole, Kelly Stefano, Murphey-Corb, Michael, Narayan, Opendra, Joag, Sanjay V., Shaw, George M., Montelaro, Ronald C.

Characterization of virus-specific immune responses to human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) is important to understanding the early virus-host...

Highly Attenuated Vaccine Strains of Simian Immunodeficiency Virus Protect against Vaginal Challenge: Inverse Relationship of Degree of Protection with Level of Attenuation

Johnson, R. Paul, Lifson, Jeffrey D., Czajak, Susan C., Cole, Kelly Stefano, Manson, Kelledy H., Glickman, Rhona, ...

Three different deletion mutants of simian immunodeficiency virus (SIV) that vary in their levels of attenuation were tested for the ability to protect against mucosal challenge with pathogenic SIV....

Immunization of Newborn Rhesus Macaques with Simian Immunodeficiency Virus (SIV) Vaccines Prolongs Survival after Oral Challenge with Virulent SIVmac251

Van Rompay, Koen K. A., Greenier, Jennifer L., Cole, Kelly Stefano, Earl, Patricia, Moss, Bernard, Steckbeck, Jonathan D., ...

There is an urgent need for active immunization strategies that, if administered shortly after birth, could protect infants in developing countries from acquiring human immunodeficiency virus (HIV)...

Removal of N-Linked Glycosylation Sites in the V1 Region of Simian Immunodeficiency Virus gp120 Results in Redirection of B-Cell Responses to V3

Cole, Kelly Stefano, Steckbeck, Jonathan D., Rowles, Jennifer L., Desrosiers, Ronald C., Montelaro, Ronald C.

One mechanism of immune evasion utilized by human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) envelope glycoproteins is the presence of a dense carbohydrate shield....

Kinetic Rates of Antibody Binding Correlate with Neutralization Sensitivity of Variant Simian Immunodeficiency Virus Strains†

Steckbeck, Jonathan D., Orlov, Irina, Chow, Andrew, Grieser, Heather, Miller, Kenneth, Bruno, JoAnne, ...

Increasing evidence suggests that an effective AIDS vaccine will need to elicit both broadly reactive humoral and cellular immune responses. Potent and cross-reactive neutralization of simian...

Common Themes of Antibody Maturation to Simian Immunodeficiency Virus, Simian-Human Immunodeficiency Virus, and Human Immunodeficiency Virus Type 1 Infections

Cole, Kelly Stefano, Murphey-Corb, Michael, Narayan, Opendra, Joag, Sanjay V., Shaw, George M., Montelaro, Ronald C.

Characterization of virus-specific immune responses to human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) is important to understanding the early virus-host...

Highly Attenuated Vaccine Strains of Simian Immunodeficiency Virus Protect against Vaginal Challenge: Inverse Relationship of Degree of Protection with Level of Attenuation

Johnson, R. Paul, Lifson, Jeffrey D., Czajak, Susan C., Cole, Kelly Stefano, Manson, Kelledy H., Glickman, Rhona, ...

Three different deletion mutants of simian immunodeficiency virus (SIV) that vary in their levels of attenuation were tested for the ability to protect against mucosal challenge with pathogenic SIV....

Immunization of Newborn Rhesus Macaques with Simian Immunodeficiency Virus (SIV) Vaccines Prolongs Survival after Oral Challenge with Virulent SIVmac251

Van Rompay, Koen K. A., Greenier, Jennifer L., Cole, Kelly Stefano, Earl, Patricia, Moss, Bernard, Steckbeck, Jonathan D., ...

There is an urgent need for active immunization strategies that, if administered shortly after birth, could protect infants in developing countries from acquiring human immunodeficiency virus (HIV)...

Removal of N-Linked Glycosylation Sites in the V1 Region of Simian Immunodeficiency Virus gp120 Results in Redirection of B-Cell Responses to V3

Cole, Kelly Stefano, Steckbeck, Jonathan D., Rowles, Jennifer L., Desrosiers, Ronald C., Montelaro, Ronald C.

One mechanism of immune evasion utilized by human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) envelope glycoproteins is the presence of a dense carbohydrate shield....

Kinetic Rates of Antibody Binding Correlate with Neutralization Sensitivity of Variant Simian Immunodeficiency Virus Strains†

Steckbeck, Jonathan D., Orlov, Irina, Chow, Andrew, Grieser, Heather, Miller, Kenneth, Bruno, JoAnne, ...

Increasing evidence suggests that an effective AIDS vaccine will need to elicit both broadly reactive humoral and cellular immune responses. Potent and cross-reactive neutralization of simian...

Rhesus Macaque Polyclonal and Monoclonal Antibodies Inhibit Simian Immunodeficiency Virus in the Presence of Human or Autologous Rhesus Effector Cells

Forthal, Donald N., Landucci, Gary, Cole, Kelly Stefano, Marthas, Marta, Becerra, Juan C., Van Rompay, Koen

Although antibodies can prevent or modulate lentivirus infections in nonhuman primates, the biological functions of antibody responsible for such effects are not known. We sought to determine the...

Vaccination of Cats with Attenuated Feline Immunodeficiency Virus Proviral DNA Vaccine Expressing Gamma Interferon▿

Gupta, Soumi, Leutenegger, Christian M., Dean, Gregg A., Steckbeck, Jonathan D., Cole, Kelly Stefano, Sparger, Ellen E.

A feline immunodeficiency virus (FIV) provirus with a vif gene deletion (FIVΔvifATGγ) that coexpresses feline gamma interferon (IFN-γ) was tested as a proviral DNA vaccine to extend previous...