Loeb, Keith R., Medical College Of Wisconsin.
Thesis, (Ph. D.)--Medical College of Wisconsin, 1993.
Loeb, Lawrence A., Loeb, Keith R., Anderson, Jon P.
Most human tumors are highly heterogenous. We have hypothesized that this heterogeneity results from a mutator phenotype. Our premise is that normal mutation rates are insufficient to account for the...
Loeb, Lawrence A., Loeb, Keith R., Anderson, Jon P.
Most human tumors are highly heterogenous. We have hypothesized that this heterogeneity results from a mutator phenotype. Our premise is that normal mutation rates are insufficient to account for the...
Human cancers express a mutator phenotype
Bielas, Jason H., Loeb, Keith R., Rubin, Brian P., True, Lawrence D., Loeb, Lawrence A.
Cancer cells contain numerous clonal mutations, i.e., mutations that are present in most or all malignant cells of a tumor and have presumably been selected because they confer a proliferative...